TAF1 antibody (C-Term)
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- Target See all TAF1 Antibodies
- TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TAF1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
- Sequence
- YEVSEEEEDE EEEEQRSGPS VLSQVHLSED EEDSEDFHSI AGDSDLDSDE
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against TAF1. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human TAF1
- Top Product
- Discover our top product TAF1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1872 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))
- Alternative Name
- TAF1 (TAF1 Products)
- Synonyms
- BG:DS00004.13 antibody, CG17603 antibody, Dmel\\CG17603 antibody, EfW1 antibody, SR3-5 antibody, TAF antibody, TAF1 antibody, TAF200 antibody, TAF230 antibody, TAF250 antibody, TAF250/230 antibody, TAFII-250 antibody, TAFII250 antibody, TAF[II]250 antibody, TAF[[II]] antibody, TAF[[II]]230 antibody, TAF[[II]]250 antibody, TAF[[II]]250/230 antibody, TFIID antibody, TFIID TAF250 antibody, Taf1p antibody, Taf200 antibody, Taf230 antibody, Taf250 antibody, Taf[[II]]250 antibody, cel antibody, cell antibody, d230 antibody, dTAF230 antibody, dTAF250 antibody, dTAFII250 antibody, dTAF[[II]]230 antibody, dTAF[[II]]250 antibody, dmTAF1 antibody, dmTAF[[II]]230 antibody, l(3)84Ab antibody, p230 antibody, 250kDa antibody, AU015687 antibody, B430306D02Rik antibody, Ccg-1 antibody, Ccg1 antibody, KAT4 antibody, N-TAF1 antibody, Taf2a antibody, RGD1562050 antibody, BA2R antibody, CCG1 antibody, CCGS antibody, DYT3 antibody, DYT3/TAF1 antibody, NSCL2 antibody, OF antibody, P250 antibody, TAF2A antibody, XDP antibody, TAF(II)250 antibody, p250 antibody, TBP-associated factor 1 antibody, TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa antibody, transcription initiation factor TFIID subunit 1 antibody, transcription initiation factor TFIID, subunit TAF1 antibody, TATA-box binding protein associated factor 1 antibody, Taf1 antibody, TAF1 antibody, LOC5567420 antibody, CpipJ_CPIJ003658 antibody, TAF11.1 antibody, HAF1501 antibody, HAF1502 antibody, LOC100457071 antibody
- Background
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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF1 encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. Two transcripts encoding different isoforms have been identified for this gene.
Alias Symbols: BA2R, CCG1, CCGS, DYT3, KAT4, NSCL2, OF, P250, TAF2A, TAFII250, XDP, N-TAF1, DYT3/TAF1
Protein Interaction Partner: AR, UBE2I, TAF4B, HIST3H3, UBC, TBP, MED26, TAF3, TAF9B, TAF7, TAF6, TAF5, TAF4, TAF2, CCNT1, GFI1B, TP53, MEN1, GTF2F1, BRMS1, PHF8, PAX3, CTCF, HIST1H4A, HIST1H3A, TAF8, MDM2, ASF1A, SIN3A, ALL1, SMARCA2, APC, RANBP2, MAX, TBPL1, TAF13, TAF10, ASF1B, TA
Protein Size: 1872 - Molecular Weight
- 215 kDa
- Gene ID
- 6872
- NCBI Accession
- NM_138923, NP_620278
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