TAF1 antibody (C-Term)
(1 reference)-
- Target See all TAF1 Antibodies
- TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))
-
Binding Specificity
- C-Term
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This TAF1 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA
- Cross-Reactivity
- Mouse (Murine), Rat (Rattus)
- Characteristics
- Concentration Definition: by UV absorbance at 280 nm
- Immunogen
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the of human TAF1.
- Isotype
- IgG
-
anti-TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) (C-Term) antibody
TAF1 Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Rabbit, Pig WB, IHC, ChIP Host: Rabbit Polyclonal unconjugated
anti-TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) (Internal Region) antibodyTAF1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) (AA 1784-1893) antibodyTAF1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1E11 unconjugated
anti-TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) (AA 1784-1893) antibodyTAF1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1G9 unconjugated
anti-TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) (C-Term) antibodyTAF1 Reactivity: Human, Dog, Horse, Pig, Chicken, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) antibodyTAF1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) (AA 1863-1893), (C-Term) antibodyTAF1 Reactivity: Mouse WB Host: Rabbit Polyclonal RB14388 unconjugated
anti-TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) (AA 1800-1849) antibodyTAF1 Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Rabbit, Pig, Chicken, Monkey, Hamster WB Host: Rabbit Polyclonal unconjugated
anti-TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) (AA 1630-1893) antibodyTAF1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
-
- Application Notes
- This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 213 kDa in size corresponding to TAF1 protein by western blotting in the appropriate cell lysate or extract.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.15 mg/mL
- Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
-
-
: "The general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells." in: Molecular and cellular biology, Vol. 32, Issue 10, pp. 1984-97, (2012) (PubMed).
-
: "The general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells." in: Molecular and cellular biology, Vol. 32, Issue 10, pp. 1984-97, (2012) (PubMed).
-
- Target
- TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))
- Alternative Name
- TAF1 (TAF1 Products)
- Synonyms
- BG:DS00004.13 antibody, CG17603 antibody, Dmel\\CG17603 antibody, EfW1 antibody, SR3-5 antibody, TAF antibody, TAF1 antibody, TAF200 antibody, TAF230 antibody, TAF250 antibody, TAF250/230 antibody, TAFII-250 antibody, TAFII250 antibody, TAF[II]250 antibody, TAF[[II]] antibody, TAF[[II]]230 antibody, TAF[[II]]250 antibody, TAF[[II]]250/230 antibody, TFIID antibody, TFIID TAF250 antibody, Taf1p antibody, Taf200 antibody, Taf230 antibody, Taf250 antibody, Taf[[II]]250 antibody, cel antibody, cell antibody, d230 antibody, dTAF230 antibody, dTAF250 antibody, dTAFII250 antibody, dTAF[[II]]230 antibody, dTAF[[II]]250 antibody, dmTAF1 antibody, dmTAF[[II]]230 antibody, l(3)84Ab antibody, p230 antibody, 250kDa antibody, AU015687 antibody, B430306D02Rik antibody, Ccg-1 antibody, Ccg1 antibody, KAT4 antibody, N-TAF1 antibody, Taf2a antibody, RGD1562050 antibody, BA2R antibody, CCG1 antibody, CCGS antibody, DYT3 antibody, DYT3/TAF1 antibody, NSCL2 antibody, OF antibody, P250 antibody, TAF2A antibody, XDP antibody, TAF(II)250 antibody, p250 antibody, TBP-associated factor 1 antibody, TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa antibody, transcription initiation factor TFIID subunit 1 antibody, transcription initiation factor TFIID, subunit TAF1 antibody, TATA-box binding protein associated factor 1 antibody, Taf1 antibody, TAF1 antibody, LOC5567420 antibody, CpipJ_CPIJ003658 antibody, TAF11.1 antibody, HAF1501 antibody, HAF1502 antibody, LOC100457071 antibody
- Background
-
This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Transcription Initiation Factor TFIID Subunit 1 (TAF1) is the largest component and core scaffold of the TFIID basal transcription factor complex, which also includes TATA-binding protein (TBP) and a variety of TBP-associated factors. TFIID nucleates the formation of transcription pre-initiation complexes and plays a key role in the regulation of gene expression by RNA polymerase II. TAF1 possesses DNA-binding activity and also contains novel N- and C-terminal Ser/Thr kinase domains which can auto-phosphorylate or trans-phosphorylate other transcription factors. For example, TAF1 interacts with the C-terminus of TP53 and phosphorylates the T55 residue, leading to MDM2-mediated degradation of TP53. TAF1 also catalyzes Ser phosphorylation of general transcription factor IIA (GTF2A1) and IIF (GTF2F1). The retinoblastoma tumor suppressor protein, RB1, interacts with the N-terminal domain of TAF1 and inhibits its intrinsic kinase activity. TAF1 is essential for progression through the G1 phase of the cell cycle and has been reported to be indispensable for expression of 18% of mammalian genes.
Synonyms: Transcription Initiation Factor TFIID Subunit 1, TAF1 - Gene ID
- 6872, 115942
- UniProt
- B1Q2X3
-
