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Browse our anti-ITPR2 (ITPR2) Antibodies

Full name:
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 2 Antibodies (ITPR2)
On www.antibodies-online.com are 33 Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2) Antibodies from 12 different suppliers available. Additionally we are shipping ITPR2 Proteins (5) and many more products for this protein. A total of 42 ITPR2 products are currently listed.
Synonyms:
AI649341, InsP3R-2, InsP3R-5, insP3R2, IP3R2, Itpr5
list all antibodies Gene Name GeneID UniProt
ITPR2 16439 Q9Z329
ITPR2 81678 P29995
ITPR2 3709 Q14571

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Most Popular Reactivities for anti-ITPR2 (ITPR2) Antibodies

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anti-Mouse (Murine) ITPR2 Antibodies:

anti-Rat (Rattus) ITPR2 Antibodies:

anti-Human ITPR2 Antibodies:

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Top referenced anti-ITPR2 Antibodies

  1. Rat (Rattus) Polyclonal ITPR2 Primary Antibody for EIA, IHC (fro) - ABIN1107880 : Mesonero, Tanfin, Hilly, Colosetti, Mauger, Harbon: Differential expression of inositol 1,4,5-trisphosphate receptor types 1, 2, and 3 in rat myometrium and endometrium during gestation. in Biology of reproduction 2000 (PubMed)

  2. Human Polyclonal ITPR2 Primary Antibody for ELISA, WB - ABIN185540 : Futatsugi, Nakamura, Yamada, Ebisui, Nakamura, Uchida, Kitaguchi, Takahashi-Iwanaga, Noda, Aruga, Mikoshiba: IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism. in Science (New York, N.Y.) 2005 (PubMed)

More Antibodies against ITPR2 Interaction Partners

Mouse (Murine) Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2) interaction partners

  1. IP3R2 KO mice had smaller infarction than WT mice in acute and chronic phases of ischemia

  2. Akt2 (show AKT2 Antibodies) upregulates dendritic cell migration at least in part by ETS1 (show ETS1 Antibodies)-dependent stimulation of IP3R2 transcription.

  3. Disrupting IP3R (show ITPR1 Antibodies)/Bcl-2 (show BCL2 Antibodies) interaction therefore leads in those cells to increased Ca(2 (show CA2 Antibodies)) release and apoptosis. Intriguingly, IP3R2 is not only implicated in apoptosis but also in the induction of senescence, another tumour-suppressive mechanism.

  4. reduced InsP3R (show ITPR1 Antibodies)-II expression is not sufficient to account for any disruptions in metabolic homeostasis that are observed in mouse models of obesity

  5. ITPR2 and hypertrophy specific gene expression is regulated, in part, by a positive feedback regulation between InsP3R2 and calcineurin (show PPP3CA Antibodies)-NFATc (show NFATC1 Antibodies) signaling pathways.

  6. This study demonistrated that hippocampal slices from inositol triphosphate receptor type 2 (IP3R2) knock-out mice which abolished the astrocytic Ca(2 (show CA2 Antibodies)+) activity.

  7. IP3R (show ITPR1 Antibodies)-deficient acinar cells accumulate zymogen granules, but the mice do not succumb to pancreatic damage or worse pancreatitis outcomes.

  8. Conclude that IP3-R (show ITPR1 Antibodies)(2) do not contribute to the progression of dilated cardiomyopathy or pressure overload hypertrophy, despite increased expression and heightened generation of the ligand, Ins (show INS Antibodies)(1,4,5)P3.

  9. Results suggest that type 2 IP(3)R (show ITPR1 Antibodies) is the major functional IP(3)R (show ITPR1 Antibodies) subtype involved in agonist-induced Ca(2 (show CA2 Antibodies)+) release in Bergmann glia

  10. serine 150 of the InsP(3)R2 is phosphorylated by CaMKII (show CAMK2G Antibodies) and results in a decrease in the channel open probability.

Human Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2) interaction partners

  1. Studies indicate that the ryanodine receptors (RyRs: RyR1 (show RYR1 Antibodies), RyR2 (show RYR2 Antibodies), RyR3 (show RYR3 Antibodies)) and inositol 1,4,5-trisphosphate receptors (IP3Rs: IP3R1 (show ITPR1 Antibodies), IP3R2, IP3R3 (show ITPR3 Antibodies)) are the major Ca(2 (show CA2 Antibodies)+) release channels (CRCs) on the endo/sarcoplasmic reticulum (ER/SR).

  2. Data suggest miR (show MLXIP Antibodies)-1290 as the new oncomiR involved in laryngeal squamous cell carcinoma pathogenesis probably through downregulation of its target genes MAF (show MAF Antibodies) and ITPR2.

  3. results show a functional role of calcium release by the ITPR2 channel and its subsequent accumulation in the mitochondria

  4. High expression of inositol 1,4,5-trisphosphate receptor, type 2 is associated with acute myeloid leukemia (show BCL11A Antibodies).

  5. Disrupting IP3R (show ITPR1 Antibodies)/Bcl-2 (show BCL2 Antibodies) interaction therefore leads in those cells to increased Ca(2 (show CA2 Antibodies)) release and apoptosis. Intriguingly, IP3R2 is not only implicated in apoptosis but also in the induction of senescence, another tumour-suppressive mechanism.

  6. A genome-wide association study identifies ITPR2 as a susceptibility gene for Kashin-Beck disease in Han Chinese.

  7. Loss of InsP3R2-mediated calcium release causes isolated anhidrosis in humans.

  8. ITPR2 and hypertrophy specific gene expression is regulated, in part, by a positive feedback regulation between InsP3R2 and calcineurin (show PPP3CA Antibodies)-NFATc (show NFATC1 Antibodies) signaling pathways.

  9. The Galphaq (show GNAQ Antibodies)-protein/coupled receptor/IP3R (show ITPR1 Antibodies) axis modulates the electromechanical properties of the human myocardium and its propensity to develop arrhythmias.

  10. Studies indicate that three subtypes of inositol 1,4,5-trisphosphate (IP3) receptors (IP3R1 (show ITPR1 Antibodies), -2, and -3) are assembled to form homo- and heterotetrameric channels that mediate Ca(2 (show CA2 Antibodies)+) release from intracellular stores.

ITPR2 Antigen Profile

Antigen Summary

receptor for inositol 1,4,5-triphosphate\; involved in regulating intracellular Ca(2+) concentration

Alternative names and synonyms associated with ITPR2

  • inositol 1,4,5-trisphosphate receptor, type 2 (ITPR2) antibody
  • inositol 1,4,5-triphosphate receptor 2 (Itpr2) antibody
  • inositol 1,4,5-trisphosphate receptor, type 2 (Itpr2) antibody
  • AI649341 antibody
  • InsP3R-2 antibody
  • InsP3R-5 antibody
  • insP3R2 antibody
  • IP3R2 antibody
  • Itpr5 antibody

Protein level used designations for ITPR2

inositol 1,4,5-trisphosphate receptor, type 2 , inositol 1,4,5-triphosphate receptor, type 2 , IP3 receptor , IP3R 2 , inositol 1,4,5-triphosphate receptor 5 , inositol 1,4,5-trisphosphate receptor type 2 , inositol 1,4,5-trisphosphate type V receptor , inositol trisphosphate receptor type 2 , type 2 InsP3 receptor , type 2 inositol 1,4,5-trisphosphate receptor , inositol 1,4,5-triphosphate receptor 2 , inositol triphosphate receptor type 2 , insP3R2

GENE ID SPECIES
100599135 Nomascus leucogenys
16439 Mus musculus
81678 Rattus norvegicus
3709 Homo sapiens
486628 Canis lupus familiaris
281878 Bos taurus
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