Browse our anti-Nuclear Receptor Coactivator 3 (NCOA3) Antibodies

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anti-Nuclear Receptor Coactivator 3 Antibodies (NCOA3)
On are 158 Nuclear Receptor Coactivator 3 (NCOA3) Antibodies from 29 different suppliers available. Additionally we are shipping Nuclear Receptor Coactivator 3 Kits (11) and Nuclear Receptor Coactivator 3 Proteins (5) and many more products for this protein. A total of 177 Nuclear Receptor Coactivator 3 products are currently listed.
2010305B15Rik, actr, aib-1, aib1, AW321064, bHLHe42, cagh16, ctg26, kat13b, NCOA3, p/Cip, pcip, rac3, src-3, src3, tnrc14, tnrc16, tram-1, Tram1, xSRC-3
list all antibodies Gene Name GeneID UniProt
NCOA3 8202 Q9Y6Q9
NCOA3 17979  
NCOA3 84584  

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Top referenced anti-Nuclear Receptor Coactivator 3 Antibodies

  1. Human Monoclonal NCOA3 Primary Antibody for IF, WB - ABIN968367 : Anzick, Kononen, Walker, Azorsa, Tanner, Guan, Sauter, Kallioniemi, Trent, Meltzer: AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. in Science (New York, N.Y.) 1997 (PubMed)
    Show all 5 references for 968367

  2. Human Polyclonal NCOA3 Primary Antibody for WB - ABIN152726 : Heemers, Regan, Schmidt, Anderson, Ballman, Tindall: Androgen modulation of coregulator expression in prostate cancer cells. in Molecular endocrinology (Baltimore, Md.) 2009 (PubMed)
    Show all 4 references for 152726

  3. Human Polyclonal NCOA3 Primary Antibody for WB - ABIN1881566 : Cai, Shames, Raso, Xie, Kim, Pollack, Girard, Sullivan, Gao, Peyton, Nanjundan, Byers, Heymach, Mills, Gazdar, Wistuba, Kodadek, Minna: Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation. in Cancer research 2010 (PubMed)
    Show all 4 references for 1881566

  4. Human Monoclonal NCOA3 Primary Antibody for ELISA, WB - ABIN968949 : Pu, Ye, Spitz, Wang, Gu, Lippman, Hildebrandt, Hong, Minna, Roth, Yang, Wu: Predictors of survival in never-smokers with non-small cell lung cancer: a large-scale, two-phase genetic study. in Clinical cancer research : an official journal of the American Association for Cancer Research 2012 (PubMed)
    Show all 2 references for 968949

  5. Human Monoclonal NCOA3 Primary Antibody for ELISA, WB - ABIN969309 : Zheng, Wu, Smith, OMalley: Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor. in Molecular and cellular biology 2005 (PubMed)
    Show all 2 references for 969309

  6. Human Monoclonal NCOA3 Primary Antibody for ICC, IF - ABIN152346 : Nakuci, Mahner, Direnzo, ElShamy: BRCA1-IRIS regulates cyclin D1 expression in breast cancer cells. in Experimental cell research 2006 (PubMed)
    Show all 2 references for 152346

  7. Cow (Bovine) Polyclonal NCOA3 Primary Antibody for IHC, WB - ABIN2779677 : Luo, Xie, Liu, Chen, Liu, Wu, Kung, Zeng, Guan: Protein expression and amplification of AIB1 in human urothelial carcinoma of the bladder and overexpression of AIB1 is a new independent prognostic marker of patient survival. in International journal of cancer. Journal international du cancer 2008 (PubMed)

More Antibodies against Nuclear Receptor Coactivator 3 Interaction Partners

Human Nuclear Receptor Coactivator 3 (NCOA3) interaction partners

  1. Estrogen receptor (show ESR1 Antibodies) recruits steroid receptor coactivator (show SRA1 Antibodies)-3 primary coactivator and secondary coactivators, p300/CBP (show CREBBP Antibodies) and CARM1 (show CARM1 Antibodies) to regulate genetic transcription.

  2. we identify a positive feedback regulatory loop consisting of XBP1 (show XBP1 Antibodies) and NCOA3 that maintains high levels of NCOA3 and XBP1 (show XBP1 Antibodies) expression in breast cancer tissues.

  3. loss of miR-17 and miR (show MLXIP Antibodies)-20b enhanced breast cancer resistance to taxol by upregulating NCOA3 levels.

  4. Data (including data from studies of hydrogen-deuterium exchange coupled to mass spectrometry in presence of denaturants) suggest that, for peptide fragments of human ACTR and mouse Crebbp (show CREBBP Antibodies) representing disordered interaction domains, exchange rates are changed dramatically by high concentrations of denaturants guanidinium chloride or urea. (ACTR = activator of thyroid and retinoid receptor; Crebbp (show CREBBP Antibodies) = CREB binding protein (show CREBBP Antibodies))

  5. Data suggest that steroid receptor (show ESR2 Antibodies) coactivators (NCOA1 (show NCOA1 Antibodies), NCOA2 (show NCOA2 Antibodies), NCOA3) are over-expressed in a number of hormone-dependent cancers where they promote tumor growth, invasion, metastasis, and chemo-resistance; with their multiple roles in cancer, steroid receptor (show ESR2 Antibodies) coactivators are promising targets for development of antineoplastic agents that can interfere with their function. [REVIEW]

  6. Here, we reported the novel finding that depletion of SRC-3 enhanced sensitivity of breast and lung cancer cells to HDAC (show HDAC3 Antibodies) inhibitors (SAHA and romidepsin). In contrast, overexpression of SRC-3 decreased SAHA-induced cancer cell apoptosis. Furthermore, we found that SRC-3 inhibitor bufalin increased cancer cell apoptosis induced by HDAC (show HDAC3 Antibodies) inhibitors. The combination of bufalin and SAHA was particular efficient in attenuating

  7. Altered expression of AIB1 may play a role in adenomyosis development and treatment outcome with levonorgestrel-releasing intrauterine system.

  8. The oncogenic transcription factor AIB1 has a novel role in the regulation of polyribosome recruitment and formation of the translational complex. Combinatorial therapies targeting IGF signaling and mRNA translation in AIB1 expressing breast cancers may have clinical benefit and warrants further investigation

  9. Total SRC3 is selectively found at enhancer regions.

  10. The transcriptional coactivator SRC-3.

Mouse (Murine) Nuclear Receptor Coactivator 3 (NCOA3) interaction partners

  1. findings show that SRC-3 contributes to host defense against enteric bacteria, at least in part via upregulating CXCL2 (show CXCL2 Antibodies) expression to recruit neutrophils

  2. Findings indicate that the Gata6 (show GATA6 Antibodies) promoter is activated by Esrrb in association with Ncoa3, and Dax1 (show NR0B1 Antibodies) inhibited activities of Esrrb and Ncoa3, resulting maintenance of the undifferentiated status of embryonic stem (ES) cells.

  3. SRC-1 (show NCOA1 Antibodies)/3 are required for cardiomyocyte proliferation and differentiation at earlier developmental stages, and their dysfunction causes NCC (show SLC12A3 Antibodies)-like abnormalities in the hearts of newborn and adult mice.

  4. AIB1 promotes gastric cancer cell proliferation, survival and invasiveness through modulating major signaling pathways such as ErbB (show EGFR Antibodies) and Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathways. Findings suggest that AIB1 plays an important role in the pathogenesis of gastric cancer.

  5. SRC-3 is a target for inhibiting aggressive prostate cancer containing neuroendocrine tumor cells.

  6. Impaired hematopoiesis and delayed thrombopoietic recovery following sublethal irradiation in SRC3 knockout mice.

  7. The p/CIP gene regulatory network identifies various feed-forward modules including one in which p/CIP activates members of the extended pluripotency network, demonstrating that p/CIP is a component of this extended network.

  8. Loss of SRC3 also shows sex differences in anxiety and exploratory behaviors.

  9. IRS1 (show IRS1 Antibodies) levels are significantly increased in mouse cell lines representing fat and muscle lineages with p/CIP and SRC-1 (show NCOA1 Antibodies) deletions and in white adipose tissue and skeletal muscle of knockout mice.

  10. Data show that knockdown of nuclear receptor coactivator 3 (Ncoa3) not only compromises the expression of pluripotency markers but also impairs in vitro and in vivo differentiation potential of embryonic stem cells.

Nuclear Receptor Coactivator 3 (NCOA3) Antigen Profile

Antigen Summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.

Alternative names and synonyms associated with Nuclear Receptor Coactivator 3 (NCOA3)

  • nuclear receptor coactivator 3 (NCOA3) antibody
  • nuclear receptor coactivator 3 (Ncoa3) antibody
  • nuclear receptor coactivator 3 (ncoa3) antibody
  • 2010305B15Rik antibody
  • actr antibody
  • aib-1 antibody
  • aib1 antibody
  • AW321064 antibody
  • bHLHe42 antibody
  • cagh16 antibody
  • ctg26 antibody
  • kat13b antibody
  • NCOA3 antibody
  • p/Cip antibody
  • pcip antibody
  • rac3 antibody
  • src-3 antibody
  • src3 antibody
  • tnrc14 antibody
  • tnrc16 antibody
  • tram-1 antibody
  • Tram1 antibody
  • xSRC-3 antibody

Protein level used designations for NCOA3

nuclear receptor coactivator 3 , CBP-interacting protein , amplified in breast cancer 1 protein , class E basic helix-loop-helix protein 42 , receptor-associated coactivator 3 , steroid receptor coactivator protein 3 , thyroid hormone receptor activator molecule 1 , steroid receptor coactivator 3 , AIB-1 , NCoA-3 , RAC-3 , SRC-3 , amplified in breast cancer-1 protein homolog , retinoid X receptor-interacting coactivator xSRC-3

705431 Macaca mulatta
8202 Homo sapiens
100135659 Sus scrofa
17979 Mus musculus
485915 Canis lupus familiaris
523707 Bos taurus
84584 Rattus norvegicus
398021 Xenopus laevis
419208 Gallus gallus
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