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anti-Dog (Canine) AGT antibody for Western Blotting

Recommended AGT Antibody (supplied by: Log in to see )

Antigen
Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) Antibodies
  • Agat
  • AGT
  • AI265500
  • AI267024
  • Ang
  • AngI
  • AngII
  • angt
  • ANGT
  • ANHU
  • ANRT
  • Aogen
  • PAT
  • Serpina8
  • SERPINA8
  • Spat
  • SPT
  • wu:fb62f06
  • wu:fj87b02
  • zgc:111892
Epitope
N-Term
27
13
12
10
8
7
5
5
5
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
166
51
47
6
2
2
1
1
1
1
Host
Rabbit
132
65
2
1
1
Clonality
Polyclonal
Conjugate
This AGT antibody is un-conjugated
14
10
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
112
88
44
26
12
12
10
8
6
4
3
3
2
1
1
1
1
Supplier
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Catalog No. ABIN2781494
$ 289.00
Plus shipping costs $45.00

Top referenced anti-AGT antibody for Western Blotting

Similar anti-AGT Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Dog (Canine)
Western Blotting (WB) 95 Antibodies 29 Antibodies 23 Antibodies 1 Antibodies
Radioimmunoassay (RIA) 2 Antibodies
Immunoprecipitation (IP) 3 Antibodies 1 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 23 Antibodies 6 Antibodies 8 Antibodies
Immunohistochemistry (IHC) 36 Antibodies 18 Antibodies 11 Antibodies 2 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies 2 Antibodies 3 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies

General

Antigen Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) Antibodies
Epitope N-Term
(27), (13), (12), (10), (8), (7), (5), (5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(166), (51), (47), (6), (2), (2), (1), (1), (1), (1)
Host Rabbit
(132), (65), (2), (1), (1)
Clonality
Polyclonal
Conjugate This AGT antibody is un-conjugated
(14), (10), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(112), (88), (44), (26), (12), (12), (10), (8), (6), (4), (3), (3), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-AGT Antibody

Target Details AGT Application Details Handling References for anti-AGT Antibody (ABIN2781494) Images
Blocking Peptide Blocking peptide for this product available: ABIN973004
Sequence IHPFHLVIHN ESTCEQLAKA NAGKPKDPTF IPAPIQAKTS PVDEKALQDQ
Predicted Reactivity Human : 100 %, Rabbit : 90 %, Mouse : 80 %
Characteristics This is a rabbit polyclonal antibody against AGT. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human AGT

Target Details AGT

Product Details anti-AGT Antibody Application Details Handling References for anti-AGT Antibody (ABIN2781494) Images back to top
Antigen
Alternative Name AGT (AGT Antibody Abstract)
Background AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Molecular Weight 53 kDa
Gene ID 183
NCBI Accession NM_000029, NP_000020
UniProt P01019
Pathways JAK-STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway

Application Details

Product Details anti-AGT Antibody Target Details AGT Handling References for anti-AGT Antibody (ABIN2781494) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 485 AA

Restrictions For Research Use only

Handling

Product Details anti-AGT Antibody Target Details AGT Application Details References for anti-AGT Antibody (ABIN2781494) Images back to top
Format Liquid
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment For short term use, store at 2-8 °C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-AGT Antibody (ABIN2781494)

Product Details anti-AGT Antibody Target Details AGT Application Details Handling Images back to top
Background publications

Ravn, Benn, Nordestgaard, Sethi, Agerholm-Larsen, Jensen, Tybjaerg-Hansen: "Angiotensinogen and ACE gene polymorphisms and risk of atrial fibrillation in the general population." in: Pharmacogenetics and genomics, Vol. 18, Issue 6, pp. 525-33, 2008

Images

Product Details anti-AGT Antibody Target Details AGT Application Details Handling References for anti-AGT Antibody (ABIN2781494) back to top
Supplier Images
Western Blotting (WB) image for anti-AGT antibody (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8)) (N-Term) (ABIN2781494) anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) (N-Term) antibody