anti-Rabbit AGT antibody for Western Blotting

Recommended AGT Antibody (supplied by: Log in to see )

Antigen
Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) Antibodies
  • wu:fb62f06
  • wu:fj87b02
  • zgc:111892
  • AGT
  • angt
  • SPT
  • Spat
  • ANHU
  • SERPINA8
  • AI265500
  • AngI
  • AngII
  • Aogen
  • Serpina8
  • ANRT
  • Ang
  • PAT
  • ANGT
  • AI267024
  • Agat
  • angiotensinogen
  • Angiotensinogen
  • alanine-glyoxylate aminotransferase
  • angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • angiotensinogen-like
  • O-6-methylguanine-DNA methyltransferase
  • agt
  • AGT
  • angt
  • Agxt
  • Agt
  • LOC100157073
  • LOC100065526
  • Mgmt
Epitope
N-Term
39
16
13
13
8
8
7
5
5
5
5
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Sheep (Ovine)
205
57
51
7
2
2
2
1
1
1
1
Host
Rabbit
153
86
2
1
1
Clonality
Polyclonal
Conjugate
This AGT antibody is un-conjugated
15
11
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
148
108
69
47
22
21
14
14
8
7
4
4
3
2
1
1
1
1
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Catalog No. ABIN2781494
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2133221 WB Rabbit IgG N-Term Log in to see Polyclonal

General

Antigen Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) Antibodies
Epitope N-Term
(39), (16), (13), (13), (8), (8), (7), (5), (5), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Dog (Canine), Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Sheep (Ovine)
(205), (57), (51), (7), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(153), (86), (2), (1), (1)
Clonality
Polyclonal
Conjugate This AGT antibody is un-conjugated
(15), (11), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(148), (108), (69), (47), (22), (21), (14), (14), (8), (7), (4), (4), (3), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-AGT Antibody

Target Details AGT Application Details Handling References for anti-AGT antibody (ABIN2781494) Images
Blocking Peptide Blocking peptide for this product available: ABIN973004
Sequence IHPFHLVIHN ESTCEQLAKA NAGKPKDPTF IPAPIQAKTS PVDEKALQDQ
Predicted Reactivity Dog: 92%, Horse: 85%, Human: 100%, Mouse: 86%, Rabbit: 92%, Rat: 93%, Sheep: 77%
Characteristics This is a rabbit polyclonal antibody against AGT. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human AGT

Target Details AGT

Product Details anti-AGT Antibody Application Details Handling References for anti-AGT antibody (ABIN2781494) Images back to top
Antigen
Alternative Name AGT (AGT Antibody Abstract)
Background AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ANHU, SERPINA8
Protein Interaction Partner: ATP6AP2, REN, ACE, ACE2, MME, ECE1, GSDMB, ITSN2, TP53, GRB2, PRG2, ENPEP, PRCP, PREP, MEP1A, AGTR2, KNG1, MAS1, EWSR1, CMA1, CTSG, AGTR1, AGT, DNPEP,
Protein Size: 485
Molecular Weight 53 kDa
Gene ID 183
NCBI Accession NM_000029, NP_000020
UniProt P01019
Pathways JAK-STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity

Application Details

Product Details anti-AGT Antibody Target Details AGT Handling References for anti-AGT antibody (ABIN2781494) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 485 AA

Restrictions For Research Use only

Handling

Product Details anti-AGT Antibody Target Details AGT Application Details References for anti-AGT antibody (ABIN2781494) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-AGT antibody (ABIN2781494)

Product Details anti-AGT Antibody Target Details AGT Application Details Handling Images back to top
Background publications

Ravn, Benn, Nordestgaard, Sethi, Agerholm-Larsen, Jensen, Tybjaerg-Hansen: "Angiotensinogen and ACE gene polymorphisms and risk of atrial fibrillation in the general population." in: Pharmacogenetics and genomics, Vol. 18, Issue 6, pp. 525-33, 2008

Images

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Supplier Images
Western Blotting (WB) image for anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) (N-Term) antibody (ABIN2781494) anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) (N-Term) antibody