|Application / Reactivity||Rat (Rattus)||Mouse (Murine)|
|ELISA||16 Antibodies||19 Antibodies|
|Enzyme Immunoassay (EIA)||1 Antibodies|
|Immunochromatography (IC)||1 Antibodies|
|Immunocytochemistry (ICC)||4 Antibodies||2 Antibodies|
|Immunofluorescence (IF)||2 Antibodies||1 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||13 Antibodies||11 Antibodies|
|Immunohistochemistry (IHC)||10 Antibodies||17 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||2 Antibodies||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||7 Antibodies||5 Antibodies|
|Immunoprecipitation (IP)||1 Antibodies||1 Antibodies|
|Western Blotting (WB)||22 Antibodies|
|Antigen||Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This AGT antibody is un-conjugated Alternatives|
Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
|6 references available|
|Supplier||Log in to see|
Product Details anti-AGT AntibodyTarget Details AGT Application Details Handling References for anti-AGT Antibody (ABIN1583980) Images
|Cross-Reactivity||Mouse (Murine), Rat (Rattus)|
|Purification||Antibody was purified by Protein-G affinity chromatography.|
|Immunogen||KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Angiotensinogen.|
Target Details AGTProduct Details anti-AGT Antibody Application Details Handling References for anti-AGT Antibody (ABIN1583980) Images back to top
|Alternative Name||Angiotensinogen (AGT Antibody Abstract)|
|Background||Angiotensinogen is the precursor of angiotensin-1 upon cleavage by renin in response to lowered blood pressure. Angiotensin-converting enzyme (ACE) then removes a dipeptide to yield the physiologically active peptide angiotensin-2, the most potent pressor substance known, which helps regulate volume and mineral balance of body fluids.|
|Pathways||JAK-STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway|
Application DetailsProduct Details anti-AGT Antibody Target Details AGT Handling References for anti-AGT Antibody (ABIN1583980) Images back to top
|Application Notes||ELISA: 1:500-1:1.000, WB: 1:200-1:500, IHC: 1:200-1:500|
|Restrictions||For Research Use only|
HandlingProduct Details anti-AGT Antibody Target Details AGT Application Details References for anti-AGT Antibody (ABIN1583980) Images back to top
|Buffer||Each vial contains 0.1 mg IgG in 0.1 mL of PBS pH7.4 with 0.09% sodium azide.|
|Precaution of Use||Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.|
|Handling Advice||Minimize freeze-thaw cycles.|
|Expiry Date||12 months|
References for anti-AGT Antibody (ABIN1583980)Product Details anti-AGT Antibody Target Details AGT Application Details Handling Images back to top
|Product cited in:||
Yang, Yao, Zhou et al.: "Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury." in: American journal of physiology. Renal physiology, Vol. 302, Issue 6, pp. F742-9, 2012 (PubMed).
Zhang, Yao, Wang et al.: "Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice." in: The Journal of clinical investigation, Vol. 121, Issue 7, pp. 2845-54, 2011 (PubMed).
Mateos, Ismail, Gil-Bea et al.: "Side chain-oxidized oxysterols regulate the brain renin-angiotensin system through a liver X receptor-dependent mechanism." in: The Journal of biological chemistry, Vol. 286, Issue 29, pp. 25574-85, 2011 (PubMed).
Mateos, Ismail, Gil-Bea et al.: "Upregulation of brain renin angiotensin system by 27-hydroxycholesterol in Alzheimer's disease." in: Journal of Alzheimer's disease : JAD, Vol. 24, Issue 4, pp. 669-79, 2011 (PubMed).
Ko, Grigoryev, Linfert et al.: "Transcriptional analysis of kidneys during repair from AKI reveals possible roles for NGAL and KIM-1 as biomarkers of AKI-to-CKD transition." in: American journal of physiology. Renal physiology, Vol. 298, Issue 6, pp. F1472-83, 2010 (PubMed).
Kang, Kim, Park et al.: "Parasympathectomy induces morphological changes and alters gene-expression profiles in the rat submandibular gland." in: Archives of oral biology, Vol. 55, Issue 1, pp. 7-14, 2010 (PubMed).
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