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anti-Mouse (Murine) IL2RG antibody for Blocking Reagent

Recommended IL2RG Antibody (supplied by: Log in to see )

Antigen
Interleukin 2 Receptor, gamma (IL2RG) Antibodies
  • Ab2-183
  • CD132
  • Cd132
  • CIDX
  • gamma(c)
  • gc
  • IL-2RG
  • IMD4
  • P64
  • SCIDX
  • SCIDX1
  • [g]c
Reactivity
Mouse (Murine)
96
48
25
2
Host
Rat
84
26
9
Clonality
Monoclonal
Conjugate
This IL2RG antibody is conjugated to Biotin
11
9
9
5
4
3
1
1
1
1
1
1
1
1
1
Application
Blocking Reagent (BR), Flow Cytometry (FACS), Neutralization (Neut)
60
45
35
11
10
5
3
2
2
1
1
1
Supplier
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Catalog No. ABIN2688956
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Top referenced anti-IL2RG antibody for Blocking Reagent

Similar anti-IL2RG Antibodies

Application / Reactivity Mouse (Murine)
Blocking Reagent (BR) 1 Antibodies
ELISA 11 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 13 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 6 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies
Intracellular Flow Cytometry (ICFC) 1 Antibodies
Neutralization (Neut) 3 Antibodies
Western Blotting (WB) 14 Antibodies

General

Antigen Interleukin 2 Receptor, gamma (IL2RG) Antibodies
Reactivity Mouse (Murine)
(96), (48), (25), (2)
Host Rat
(84), (26), (9)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL2RG antibody is conjugated to Biotin
(11), (9), (9), (5), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Blocking Reagent (BR), Flow Cytometry (FACS), Neutralization (Neut)
(60), (45), (35), (11), (10), (5), (3), (2), (2), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-IL2RG Antibody

Target Details IL2RG Application Details Handling References for anti-IL2RG Antibody (ABIN2688956) Images
Brand BD Pharmingen™
Characteristics The TUGm2 antibody reacts with Mouse CD132 which is also known as the common γ subunit (γc). The γc chain subunit is shared by the IL-2, IL-4, IL-7, IL-9, and IL-15 receptor complexes. The γc receptor is expressed constitutively at low levels by most lymphocytes, myeloid cells, embryonic thymocytes, and lymphoid cell lines. The γc receptor is a 75-80 kD transmembrane glycoprotein which mediates signal transducing activities of cytokine receptor complexes with which it is associated. TUGm2 antibody can significantly block the binding of and proliferative response to IL-4 by CTLL-2 cells. It can also inhibit binding to high-affinity IL-2 receptors expressed by CTLL-2 cells. By itself, the TUGm2 antibody reportedly fails to significantly inhibit CTLL-2 proliferative responses to IL-2. However, when added along with TM-β1 (Cat. No. 553359), specific for the mouse IL-2Rβ chain, TUGm2 was shown to synergistically reduce IL-2-driven CTLL-2 proliferative responses. TUGm2 can reduce the IL-7-induced proliferation of Con A-activated mouse splenocytes and the IL-7 responsive pre-B cell line, IxN/2b. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

BD Pharmingen™ Biotin Rat Anti-Mouse CD132 - Biotin - Clone TUGm2 - Isotype Rat IgG2b, κ - Reactivity Ms - 0.5 mg
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Clone TUGm2
Isotype IgG2b, kappa

Target Details IL2RG

Product Details anti-IL2RG Antibody Application Details Handling References for anti-IL2RG Antibody (ABIN2688956) Images back to top
Antigen
Alternative Name CD132 (IL2RG Antibody Abstract)
Background Synonyms: Cytokine Common γ chain, γc
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL2RG Antibody Target Details IL2RG Handling References for anti-IL2RG Antibody (ABIN2688956) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL2RG Antibody Target Details IL2RG Application Details References for anti-IL2RG Antibody (ABIN2688956) Images back to top
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
Storage 4 °C
Storage Comment Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

References for anti-IL2RG Antibody (ABIN2688956)

Product Details anti-IL2RG Antibody Target Details IL2RG Application Details Handling Images back to top
Product cited in:

Kondo, Takeshita, Higuchi, Nakamura, Sudo, Nishikawa, Sugamura: "Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes." in: Science (New York, N.Y.), Vol. 263, Issue 5152, pp. 1453-4, 1994

Kondo, Takeshita, Ishii, Nakamura, Watanabe, Arai, Sugamura: "Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4." in: Science (New York, N.Y.), Vol. 262, Issue 5141, pp. 1874-7, 1994

Guesdon, Ternynck, Avrameas: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, 1979