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Browse our anti-IRF9 (IRF9) Antibodies

Full name:
anti-Interferon Regulatory Factor 9 Antibodies (IRF9)
On www.antibodies-online.com are 74 Interferon Regulatory Factor 9 (IRF9) Antibodies from 21 different suppliers available. Additionally we are shipping IRF9 Kits (4) and IRF9 Proteins (4) and many more products for this protein. A total of 88 IRF9 products are currently listed.
Synonyms:
Irf-9, ISGF3, Isgf3g, p48, zgc:92097
list all antibodies Gene Name GeneID UniProt
IRF9 10379 Q00978
IRF9 16391 Q61179
IRF9 305896  

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Most Popular Reactivities for anti-IRF9 (IRF9) Antibodies

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anti-Human IRF9 Antibodies:

anti-Mouse (Murine) IRF9 Antibodies:

anti-Rat (Rattus) IRF9 Antibodies:

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Top referenced anti-IRF9 Antibodies

  1. Human Monoclonal IRF9 Primary Antibody for IF, IP - ABIN967883 : Dumler, Kopmann, Wagner, Mayboroda, Jerke, Dietz, Haller, Gulba: Urokinase induces activation and formation of Stat4 and Stat1-Stat2 complexes in human vascular smooth muscle cells. in The Journal of biological chemistry 1999 (PubMed)
    Show all 3 references for ABIN967883

  2. Cow (Bovine) Polyclonal IRF9 Primary Antibody for IHC, WB - ABIN2777226 : Schumacher, Lau, Johnson: Structural basis of core promoter recognition in a primitive eukaryote. in Cell 2003 (PubMed)
    Show all 3 references for ABIN2777226

  3. Human Monoclonal IRF9 Primary Antibody for FACS - ABIN2666230 : Fink, Grandvaux: STAT2 and IRF9: Beyond ISGF3. in JAK-STAT 2014 (PubMed)
    Show all 3 references for ABIN2666230

  4. Mouse (Murine) Polyclonal IRF9 Primary Antibody for IF, IHC (p) - ABIN655818 : Mosbruger, Duggal, Goedert, Kirk, Hoots, Tobler, Busch, Peters, Rosen, Thomas, Thio: Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. in The Journal of infectious diseases 2010 (PubMed)
    Show all 2 references for ABIN655818

  5. Human Monoclonal IRF9 Primary Antibody for IHC (p), ELISA - ABIN564508 : Kyriakidis, Kapsogeorgou, Gourzi, Konsta, Baltatzis, Tzioufas: Toll-like receptor 3 stimulation promotes Ro52/TRIM21 synthesis and nuclear redistribution in salivary gland epithelial cells, partially via type I interferon pathway. in Clinical and experimental immunology 2014 (PubMed)

More Antibodies against IRF9 Interaction Partners

Pig (Porcine) Interferon Regulatory Factor 9 (IRF9) interaction partners

  1. Single nucleotide polymorphism c.459A > G in the IRF9 gene significantly decreased the IFN-gamma (show IFNG Antibodies) concentration and increased the ratio of IFN-gamma (show IFNG Antibodies)/IL-10 (show IL10 Antibodies) in serum of piglets after challenged with classical swine fever vaccine.

Human Interferon Regulatory Factor 9 (IRF9) interaction partners

  1. Interferonstimulated gene factor 3 complex, which consists of STAT1 (show STAT1 Antibodies), STAT2 (show STAT2 Antibodies) and IRF9, is required for the induction of SAMHD1 (show SAMHD1 Antibodies) expression by IFN-alpha (show IFNA Antibodies) in SMMC-7721 cells.

  2. U-ISGF3 (show STAT1 Antibodies) induced by IFN-lambdas and -beta drives prolonged expression of a set of IFN-stimulated genes during HCV infection

  3. IRF9 is a vascular injury-response molecule that promotes VSMC proliferation. IRF9 expression is upregulated during neointima formation.

  4. DC-SIGN (show CD209 Antibodies)-induced ISGF3 (show STAT1 Antibodies) by fucose-based PAMPs has an essential role in driving IL-27 (show IL27 Antibodies) and subsequent TFH polarization, which might be harnessed for vaccination design

  5. IRF9 mediated myocardial reperfusion injury

  6. STAT2 (show STAT2 Antibodies) and IRF9 overexpression is sufficient to drive interferon (show IFNA Antibodies)-related DNA damage signature expression upon cell crowding.

  7. IL6 (show IL6 Antibodies) is an inducer of IRF9 expression in prostate cancer and a sensitizer for the antiproliferative effects of IFNalpha2 (show IFNA2 Antibodies).

  8. The hepatitis C virus (HCV) non-structural 5A (NS5A) protein, which is known to modulate the IFN response, competes with IRF9 for CypA (show PPIA Antibodies) binding and can prevent the formation of IRF9-CypA (show PPIA Antibodies) complexes.

  9. HDAC1 (show HDAC1 Antibodies) and HDAC2 (show HDAC2 Antibodies) differentially modulate STAT (show STAT1 Antibodies) activity in response to IFNalpha2 (show IFNA2 Antibodies): while they are required for the induction of ISGF3 (show STAT1 Antibodies)-responsive genes, they impair the transcription of STAT3 (show STAT3 Antibodies)-dependent genes.

  10. Western blot and electrophoretic mobility-shift assays identified the interferon (show IFNA Antibodies)-stimulated gene factor-3 (ISGF-3 (show STAT1 Antibodies)) components STAT1 (show STAT1 Antibodies) and IRF-9 as the proximal targets of human herpesvirus 8 vIRF-2 activity.

Zebrafish Interferon Regulatory Factor 9 (IRF9) interaction partners

  1. Much more significant induction of zebrafish IRF9 by zebrafish IFNgamma2.

Mouse (Murine) Interferon Regulatory Factor 9 (IRF9) interaction partners

  1. IRF9 is a vascular injury-response molecule that promotes VSMC proliferation. IRF9 expression is upregulated during neointima formation.

  2. IFN-alpha (show IFNA Antibodies)/beta is able to drive the formation of a Stat2 (show STAT2 Antibodies) and IRF-9 complex that drives the expression of a subset of IFN-stimulated genes, but with substantially delayed kinetics.

  3. In a murine model of dextran sodium sulfate -induced colitis, IRF9 deficiency protects animals, whereas the combined loss of interferon (show IFNA Antibodies) I and interferon (show IFNA Antibodies) III receptors worsens their condition.

  4. STAT2 (show STAT2 Antibodies)/IRF9 regulates antiviral activity through a prolonged ISGF3-like transcriptional response.

  5. IRF9 mediated myocardial reperfusion injury

  6. IRF9 directly activates neuronal death signaling pathways through the downregulation of Sirt1 (show SIRT1 Antibodies) deacetylase in response to acute I/R stress.

  7. IFN-beta (show IFNB1 Antibodies)-induced necroptosis of macrophages proceeds through tonic IFN-stimulated gene factor 3 (ISGF3) signaling, which leads to persistent expression of STAT1 (show STAT1 Antibodies), STAT2 (show STAT2 Antibodies), and IRF9 and sustained Rip3 (show MPRIP Antibodies) activation.

  8. IRF9 inhibits the development of cardiac hypertrophy by suppressing the transcriptional activity of myocardin (show MYOCD Antibodies) in the heart.

  9. Interferon regulatory factor 9 protects against hepatic insulin (show INS Antibodies) resistance and steatosis in male mice.

  10. STAT1 (show STAT1 Antibodies), not STAT2 (show STAT2 Antibodies) or IRF9, prevent the emergence of a lethal antiviral CD4 (show CD4 Antibodies)(+) T-cell response after lymphocytic choriomeningitis virus infection.

IRF9 Antigen Profile

Antigen Summary

Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Alternative names and synonyms associated with IRF9

  • interferon regulatory factor 9 (LOC780415) antibody
  • interferon-stimulated transcription factor 3, gamma 48kDa (LOC100344432) antibody
  • interferon regulatory factor 9 (IRF9) antibody
  • interferon regulatory factor 9 (irf9) antibody
  • interferon regulatory factor 9 (Irf9) antibody
  • Irf-9 antibody
  • ISGF3 antibody
  • Isgf3g antibody
  • p48 antibody
  • zgc:92097 antibody

Protein level used designations for IRF9

interferon regulatory factor 9 , interferon-stimulated transcription factor 3, gamma 48kDa , IFN-alpha-responsive transcription factor subunit , ISGF-3 gamma , ISGF3 p48 subunit , interferon-stimulated gene factor 3 gamma , interferon-stimulated transcription factor 3, gamma (48kD) , transcriptional regulator ISGF3 subunit gamma , interferon dependent positive acting transcription factor 3 gamma

GENE ID SPECIES
780415 Sus scrofa
100344432 Oryctolagus cuniculus
10379 Homo sapiens
403013 Danio rerio
509855 Bos taurus
16391 Mus musculus
305896 Rattus norvegicus
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