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anti-Human STAT2 antibody for Western Blotting

Recommended STAT2 Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) Antibodies
  • 1600010G07Rik
  • AW496480
  • ISGF-3
  • P113
  • p113
  • stat2
  • STAT113
  • wu:fj84d07
Epitope
pTyr690
43
42
22
17
15
15
13
13
11
9
8
5
5
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
217
79
57
4
3
3
3
3
3
3
3
Host
Mouse
229
24
1
Clonality
Monoclonal
Conjugate
This STAT2 antibody is un-conjugated
10
9
8
6
6
6
2
2
2
2
2
2
2
2
2
1
Application
Western Blotting (WB)
203
92
91
29
23
22
7
4
4
3
3
3
1
1
1
1
Supplier
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Catalog No. ABIN967579
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.12316538 ABIN967807 IF IP IHC WB Mouse IgG2a AA 1-178 Log in to see 22-Stat2 5
0.12316538 ABIN967806 IF IP IHC WB Mouse IgG2a AA 1-178 Log in to see 22-Stat2 5
0.12316538 ABIN1531245 IHC ELISA WB Rabbit IgG pTyr690 Log in to see Polyclonal
0.12316538 ABIN657671 IHC (p) WB Rabbit Ig AA 186-215, N-Term Log in to see Polyclonal
0.12316538 ABIN964699 ELISA WB Mouse IgG2a kappa C-Term Log in to see 19G8-H2-H6
0.12316538 ABIN964700 ELISA WB Mouse IgG2a kappa Log in to see 19G8-H2-H6
0.12316538 ABIN411595 WB Rabbit IgG Log in to see Polyclonal
0.12316538 ABIN1532263 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.12316538 ABIN3043177 WB Rabbit IgG AA 796-814, C-Term Log in to see Polyclonal
0.12316538 ABIN349594 ELISA WB Rabbit IgG N-Term, pTyr690 Log in to see Polyclonal
0.12316538 ABIN2705257 IHC WB Rabbit C-Term, pTyr690 Log in to see Polyclonal
0.12316538 ABIN1870639 WB Rabbit IgG pTyr690 Log in to see Polyclonal
0.12316538 ABIN388366 IHC (p) WB Rabbit Ig AA 820-851, C-Term Log in to see Polyclonal
0.12316538 ABIN964892 ELISA WB Rabbit IgG pTyr690, Internal Region Log in to see Polyclonal
0.12316538 ABIN2505983 IHC WB Rabbit IgG Tyr690 Log in to see Polyclonal
0.12316538 ABIN2505987 IHC ELISA WB Rabbit IgG pTyr690 Log in to see Polyclonal
0.12316538 ABIN2855558 IP IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
0.12316538 ABIN393838 IF WB Mouse IgG1 kappa AA 742-851 Log in to see 5G7
0.12316538 ABIN2505986 IHC ELISA WB Rabbit IgG Tyr690 Log in to see Polyclonal
0.12316538 ABIN1874963 IHC WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-STAT2 antibody for Western Blotting

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General

Antigen Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) Antibodies
Epitope pTyr690
(43), (42), (22), (17), (15), (15), (13), (13), (11), (9), (8), (5), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(217), (79), (57), (4), (3), (3), (3), (3), (3), (3), (3)
Host Mouse
(229), (24), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This STAT2 antibody is un-conjugated
(10), (9), (8), (6), (6), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Western Blotting (WB)
(203), (92), (91), (29), (23), (22), (7), (4), (4), (3), (3), (3), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-STAT2 Antibody

Target Details STAT2 Application Details Handling References for anti-STAT2 Antibody (ABIN967579) Images
Brand BD Pharmingen™
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Phosphorylated Human Stat2 Peptide
Clone 7a-Stat2
Isotype IgG1, kappa

Target Details STAT2

Product Details anti-STAT2 Antibody Application Details Handling References for anti-STAT2 Antibody (ABIN967579) Images back to top
Antigen
Alternative Name Stat2 (STAT2 Antibody Abstract)
Background Stat (Signal transducer and activators of transcription) proteins are critical mediators of the biologic activity of cytokines, including interleukins, interferons, erythropoietin, and growth factors. Ligand-receptor interaction leads to activation of constitutively associated JAK family kinases and subsequent recruitment/activation of Stat proteins by tyrosine phosphorylation. Active Stat proteins then move to the nucleus to promote transcription of cytokine-inducible genes. Seven Stat proteins have been cloned, each of which is differentially expressed and/or activated in a cytokine-specific and cell type-specific manner. Stat1 and Stat2 are components of the ISGF3 (Interferon-Stimulated Gene Factor 3) complex, which is the primary transcription activator induced by the binding of the interferon to a specific cell-surface receptor. Stat2 is a 113-kDa protein having approximately 40% homology with Stat1a. Stat2 interacts with Stat1 for the efficient activation of Stat1 in response to IFN-a, which is essential for normal transcriptional activity of the ISGF3 complex. Stat2 phosphorylation at the tyrosine 690 residue (Y690) after IFN-a activation can occur independently of Stat1, but the localization and nuclear stability of phosphorylated Stat2 is dependent on Stat1.
The 7a/Stat2 monoclonal antibody recognizes the phosphorylated Y690 of human Stat2.
Molecular Weight 113 kDa
Research Area Signaling, Receptors, Inflammation
Pathways JAK-STAT Signaling

Application Details

Product Details anti-STAT2 Antibody Target Details STAT2 Handling References for anti-STAT2 Antibody (ABIN967579) Images back to top
Comment

Related Products: ABIN967389

Restrictions For Research Use only

Handling

Product Details anti-STAT2 Antibody Target Details STAT2 Application Details References for anti-STAT2 Antibody (ABIN967579) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4°C.

References for anti-STAT2 Antibody (ABIN967579)

Product Details anti-STAT2 Antibody Target Details STAT2 Application Details Handling Images back to top
Product cited in:

Bromberg, Darnell: "The role of STATs in transcriptional control and their impact on cellular function." in: Oncogene, Vol. 19, Issue 21, pp. 2468-73, 2000

Heim: "The Jak-STAT pathway: specific signal transduction from the cell membrane to the nucleus." in: European journal of clinical investigation, Vol. 26, Issue 1, pp. 1-12, 1996

Images

Product Details anti-STAT2 Antibody Target Details STAT2 Application Details Handling References for anti-STAT2 Antibody (ABIN967579) back to top
Supplier Images
Western Blotting (WB) image for anti-STAT2 antibody (Signal Transducer and Activator of Transcription 2, 113kDa) (pTyr690) (ABIN967579) Western Blot analysis of Stat2 (pY690) in human histiocytic lymphoma. Lysates from co...