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anti-Rat (Rattus) STAT5B antibody for Immunohistochemistry

Recommended STAT5B Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 5B (STAT5B) Antibodies
  • STAT5A
  • Stat5
  • stat5
  • stat5b
  • STAT5
  • signal transducer and activator of transcription 5B
  • Signal transducer and activator of transcription 5B
  • signal transducer and activator of transcription 5.1
  • signal transducer and activator of transcription 5B-like
  • STAT5B
  • sta5b
  • stat5b
  • stat5.1
  • Stat5b
  • LOC789476
  • LOC100348267
Epitope
N-Term
34
22
10
10
6
5
5
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Goat, Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine), Zebrafish
204
98
92
14
13
12
10
8
6
6
5
3
2
2
1
1
Host
Rabbit
140
71
Clonality
Polyclonal
Conjugate
This STAT5B antibody is un-conjugated
4
4
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
158
71
62
35
29
26
17
16
7
3
3
2
1
1
1
1
Options
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Catalog No. ABIN2780884
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
9.2386675 ABIN2780885 IHC WB Rabbit C-Term Log in to see Polyclonal 1
9.2386675 ABIN2779971 IHC WB Rabbit Middle Region Log in to see Polyclonal 1
9.2386675 ABIN1532264 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 1
9.2386675 ABIN2779972 IHC WB Rabbit C-Term Log in to see Polyclonal
9.2386675 ABIN1531246 IHC ELISA WB Rabbit IgG pSer731 Log in to see Polyclonal
9.2386675 ABIN3188052 IHC WB Rabbit IgG Log in to see Polyclonal
9.2386675 ABIN1874969 IF IHC WB Rabbit IgG Log in to see Polyclonal
9.2386675 ABIN3020858 IHC WB Rabbit IgG Log in to see Polyclonal
9.2386675 ABIN2967070 IC IF IHC WB Rabbit Log in to see Polyclonal
9.2386675 ABIN2403556 IF IHC WB Rabbit IgG Log in to see Polyclonal
9.2386675 ABIN2427595 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
9.2386675 ABIN2421011 IHC ELISA Rabbit IgG Log in to see Polyclonal
9.2386675 ABIN1847250 IHC ELISA WB Rabbit C-Term, pSer726, pSer731, pSer725 Log in to see Polyclonal
1 ABIN2891933 IHC WB Rabbit Tyr725 Log in to see Polyclonal
1 ABIN2887923 IF IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2866570 IHC WB Rabbit Log in to see Polyclonal
1 ABIN1092393 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1092394 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1845634 IHC WB Rabbit pSer731 Log in to see Polyclonal
1 ABIN1845636 IHC WB Rabbit Log in to see Polyclonal

Top referenced anti-STAT5B antibody for Immunohistochemistry

Similar anti-STAT5B Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Cow (Bovine) Dog (Canine) Pig (Porcine) Zebrafish Horse (Equine) Guinea Pig Rabbit Sheep (Ovine) Goat
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies 2 Antibodies 2 Antibodies
Simple Western (SimWes) 1 Antibodies 1 Antibodies
Western Blotting (WB) 13 Antibodies 15 Antibodies 152 Antibodies 73 Antibodies 14 Antibodies 66 Antibodies 7 Antibodies 11 Antibodies 6 Antibodies 9 Antibodies 4 Antibodies 2 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 9 Antibodies

General

Antigen Signal Transducer and Activator of Transcription 5B (STAT5B) Antibodies
Epitope N-Term
(34), (22), (10), (10), (6), (5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Goat, Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine), Zebrafish
(204), (98), (92), (14), (13), (12), (10), (8), (6), (6), (5), (3), (2), (2), (1), (1)
Host Rabbit
(140), (71)
Clonality
Polyclonal
Conjugate This STAT5B antibody is un-conjugated
(4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(158), (71), (62), (35), (29), (26), (17), (16), (7), (3), (3), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-STAT5B Antibody

Target Details STAT5B Application Details Handling References for anti-STAT5B Antibody (ABIN2780884) Images
Blocking Peptide Blocking peptide for this product available: ABIN984535
Sequence AVWIQAQQLQ GEALHQMQAL YGQHFPIEVR HYLSQWIESQ AWDSVDLDNP
Predicted Reactivity Cow: 93%, Dog: 100%, Goat: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 86%, Zebrafish: 86%
Characteristics This is a rabbit polyclonal antibody against STAT5B. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human STAT5B

Target Details STAT5B

Product Details anti-STAT5B Antibody Application Details Handling References for anti-STAT5B Antibody (ABIN2780884) Images back to top
Antigen
Alternative Name STAT5B (STAT5B Antibody Abstract)
Background The protein is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: STAT5
Protein Interaction Partner: JAK2, KIT, SURF2, AARS, DPP9, NIF3L1, RPRD1B, ANKMY2, RPRD1A, TOM1L1, DMRTA1, AFTPH, SERTAD1, HAX1, TFG, VCAM1, UBC, INSR, IL15, APP, C18orf8, STAT5B, PRLR, PGR, FGFR2, POU2F1, ELP2, CENPJ, PPP2CA, STAP2, RARA, PTPN2, NMI, EP300, CRKL, STAT5A, GHR, NCOR2,
Protein Size: 787
Molecular Weight 90 kDa
Gene ID 6777
NCBI Accession NM_012448, NP_036580
UniProt P51692
Pathways JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation

Application Details

Product Details anti-STAT5B Antibody Target Details STAT5B Handling References for anti-STAT5B Antibody (ABIN2780884) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 787 AA

Restrictions For Research Use only

Handling

Product Details anti-STAT5B Antibody Target Details STAT5B Application Details References for anti-STAT5B Antibody (ABIN2780884) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-STAT5B Antibody (ABIN2780884)

Product Details anti-STAT5B Antibody Target Details STAT5B Application Details Handling Images back to top
Background publications

Mohankumar, Perry, Kannan, Kohno, Gluckman, Emerald, Lobie: "Transcriptional activation of signal transducer and activator of transcription (STAT) 3 and STAT5B partially mediate homeobox A1-stimulated oncogenic transformation of the immortalized human mammary epithelial cell." in: Endocrinology, Vol. 149, Issue 5, pp. 2219-29, 2008

Images

Product Details anti-STAT5B Antibody Target Details STAT5B Application Details Handling References for anti-STAT5B Antibody (ABIN2780884) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-STAT5B antibody (Signal Transducer and Activator of Transcription 5B) (N-Term) (ABIN2780884) Anti-STAT5B antibody IHC staining of human placenta. Immunohistochemistry of formalin...
Immunohistochemistry (IHC) image for anti-STAT5B antibody (Signal Transducer and Activator of Transcription 5B) (N-Term) (ABIN2780884) Anti-STAT5B antibody IHC staining of human prostate. Immunohistochemistry of formalin...
Immunohistochemistry (IHC) image for anti-STAT5B antibody (Signal Transducer and Activator of Transcription 5B) (N-Term) (ABIN2780884) Rabbit Anti-STAT5B Antibody Catalog Number: arp39000 Paraffin Embedded Tissue: Human ...
Western Blotting (WB) image for anti-STAT5B antibody (Signal Transducer and Activator of Transcription 5B) (N-Term) (ABIN2780884) WB Suggested Anti-STAT5B Antibody Titration: 1 ug/ml Positive Control: 293T cells lys...