STAT5B antibody (pSer731)

Catalog No. ABIN7138690

Product Details anti-STAT5B Antibody

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Binding Specificity: pSer731

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAT5B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 731 (A-P-S(p)-P-A) derived from Human STAT5B.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for STAT5B

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Alternative Name: STAT5B (STAT5B Products)

Synonyms: STAT5 antibody, stat5 antibody, STAT5A antibody, STAT5B antibody, signal transducer and activator of transcription 5B antibody, signal transducer and activator of transcription 5B S homeolog antibody, Signal transducer and activator of transcription 5B antibody, STAT5B antibody, Stat5b antibody, stat5b.S antibody, LOC490969 antibody, sta5b antibody, LOC100566752 antibody, LOC100052954 antibody

Background:

Background: Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.

Aliases: Signal transducer and activator of transcription 5B antibody, STA5B_HUMAN antibody, STAT5 antibody, Stat5b antibody, Transcription factor STAT5B antibody

UniProt: P51692

Pathways: JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation