anti-Mouse (Murine) TYK2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended TYK2 Antibody (supplied by: Log in to see )

Antigen
Tyrosine Kinase 2 (TYK2) Antibodies
  • JTK1
  • tyrosine kinase 2
  • tyrosine kinase 2-like
  • TYK2
  • Tyk2
  • LOC100344622
Reactivity
Human, Mouse (Murine)
176
73
59
3
2
2
1
1
1
Host
Rabbit
142
35
Clonality
Polyclonal
Conjugate
This TYK2 antibody is un-conjugated
7
7
7
5
5
5
2
2
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
106
72
65
27
26
22
12
10
2
1
1
Supplier
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Catalog No. ABIN498981
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.403178 ABIN214066 IHC (p) Rabbit IgG Tyr1054 Log in to see Polyclonal
1 ABIN302946 IHC (p) Rabbit IgG Log in to see Polyclonal
1 ABIN2879297 IF IHC (p) WB Rabbit Val1048 Log in to see Polyclonal
1 ABIN1740492 IHC (p) Rabbit IgG Log in to see Polyclonal
1 ABIN719600 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN746327 IHC (p) WB HRP Rabbit IgG pTyr1054, pTyr1055 Log in to see Polyclonal
1 ABIN1823002 IHC (p) Rabbit IgG pTyr1054 Log in to see Polyclonal
1 ABIN719593 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN746320 IHC (p) WB Biotin Rabbit IgG pTyr1054, pTyr1055 Log in to see Polyclonal
1 ABIN719591 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN746318 IF (p) IHC (p) WB Rabbit IgG pTyr1054, pTyr1055 Log in to see Polyclonal
1 ABIN1945961 IHC (p) ELISA WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN2964549 IHC (p) ELISA WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN701290 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN4363627 IHC IHC (p) Rabbit IgG Tyr1054 Log in to see Polyclonal
1 ABIN2964548 IF IHC (p) WB Rabbit Val1048 Log in to see Polyclonal

Similar anti-TYK2 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 7 Antibodies 71 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 11 Antibodies
Immunofluorescence (IF) 5 Antibodies 23 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 27 Antibodies
Immunohistochemistry (IHC) 20 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 17 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 37 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 1 Antibodies

General

Antigen Tyrosine Kinase 2 (TYK2) Antibodies
Reactivity Human, Mouse (Murine)
(176), (73), (59), (3), (2), (2), (1), (1), (1)
Host Rabbit
(142), (35)
Clonality
Polyclonal
Conjugate This TYK2 antibody is un-conjugated
(7), (7), (7), (5), (5), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(106), (72), (65), (27), (26), (22), (12), (10), (2), (1), (1)
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Product Details anti-TYK2 Antibody

Target Details TYK2 Application Details Handling Images
Specificity This antibody detects endogenous levels of Tyk 2 protein. (region surrounding Val1048)
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse.
Purification Affinity chromatography
Purity > 95 % by SDS-PAGE

Target Details TYK2

Product Details anti-TYK2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TYK2 (TYK2 Antibody Abstract)
Background Tyk 2 belongs to the family of non-receptor janus tyrosine kinases, which regulate a spectrum of cellular functions occurring downstream of activated cytokine receptors in the lympho-hematopoietic system. Immunological stimuli, such as interferons and cytokines, recruit STAT transcription factors to the cytokine receptor where Tyk 2 is associated. Tyk 2 then phosphorylates proximal STAT factors, which subsequently dimerize, translocate to the nucleus, and bind to cis elements upstream of target gene promoters to regulating transcription. The canonical JAK-STAT pathway is integral to maintaining a normal immune system by stimulating proliferation, differentiation, survival, and host resistance to pathogens. Cytokine induced pro-inflammatory responses are attractive targets for anti-inflammatory therapies, specifically at the level of Jak-STAT signaling.Synonyms: JTK1, Non-receptor tyrosine-protein kinase TYK2
Molecular Weight approx. 134 kDa
Gene ID 7297
NCBI Accession NP_003322
UniProt P29597
Research Area Signaling, Tyrosine Kinases
Pathways JAK-STAT Signaling, Hepatitis C

Application Details

Product Details anti-TYK2 Antibody Target Details TYK2 Handling Images back to top
Application Notes Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TYK2 Antibody Target Details TYK2 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-TYK2 Antibody Target Details TYK2 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-TYK2 antibody (Tyrosine Kinase 2) (ABIN498981) Immunohistochemistry (IHC) analyzes of Tyk 2 antibody in paraffin-embedded hum...
Western Blotting (WB) image for anti-TYK2 antibody (Tyrosine Kinase 2) (ABIN498981) Western blot (WB) analysis of Tyk 2 antibody in extracts from 293cells.