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|Antigen||Tyrosine Kinase 2 (TYK2) Antibodies|
|Epitope||pTyr1054, pTyr1055 Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This TYK2 antibody is conjugated to Cy3 Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
|Supplier||Log in to see|
Product Details anti-TYK2 AntibodyTarget Details TYK2 Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic phosphopeptide derived from human Tyk2 around the phosphorylation site of Tyr1054/1055|
Target Details TYK2Product Details anti-TYK2 Antibody Application Details Handling Images back to top
|Alternative Name||Tyk2 (TYK2 Antibody Abstract)|
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq].
Synonyms: TYK2Tyr1054/1055, Tyk2phospho Y1054/1055, TYK2 phospho Tyr1054/1055, p-TYK2 Tyr1054/1055, JTK 1, JTK1, TYK 2, Non receptor tyrosine protein kinase 2, Non receptor tyrosine protein kinase TYK2, Protein Tyrosine Kinase 2, Tyrosine kinase 2, TYK2_HUMAN, Non-receptor tyrosine-protein kinase TYK2.
|Pathways||JAK-STAT Signaling, Hepatitis C|
Application DetailsProduct Details anti-TYK2 Antibody Target Details TYK2 Handling Images back to top
|Application Notes||IF(IHC-P) 1:50-200|
|Restrictions||For Research Use only|
HandlingProduct Details anti-TYK2 Antibody Target Details TYK2 Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|