anti-Human EIF4EBP1 antibody for Flow Cytometry

Recommended EIF4EBP1 Antibody (supplied by: Log in to see )

Antigen
Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Antibodies
  • 153432_at
  • 43-BP
  • 4E-BP
  • 4E-BP1
  • 4EBP
  • 4e-bp
  • 4eBP
  • 4ebp
  • BcDNA.HL08053
  • BcDNA:HL08053
  • CG8846
  • CT8705
  • Dm 4E-BP
  • Dmel\\CG8846
  • Phas1
  • Thor/EIF4EBP
  • anon-WO0172774.158
  • d4E-BP
  • d4E-BP1
  • d4EBP
  • d4e-bp
  • d4eBP
  • dthor
  • eIF4E-BP
  • l(2)06270
  • l(2)k07736
  • l(2)k13517
  • pp20
  • thor
  • EIF4EBP1
  • fc04h09
  • wu:fc04h09
  • zgc:64137
  • 4EBP1
  • BP-1
  • PHAS-I
  • 4e-bp1
  • AA959816
  • CG8846 gene product from transcript CG8846-RA
  • eukaryotic translation initiation factor 4E binding protein 1
  • Thor
  • EIF4EBP1
  • eif4ebp1
  • LOC100230789
  • Eif4ebp1
Epitope
AA 2-118
61
36
29
29
27
22
19
16
15
15
15
15
14
12
12
8
8
7
6
5
5
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
461
278
236
20
17
13
9
5
5
5
3
2
2
1
1
1
1
1
Host
Mouse
402
96
4
Clonality
Monoclonal
Conjugate
This EIF4EBP1 antibody is conjugated to PE
19
17
11
9
8
8
5
5
5
5
5
5
5
5
5
5
5
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
346
216
201
111
66
30
17
17
14
8
7
6
5
4
3
1
Supplier
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Catalog No. ABIN1995478
$ 198.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
14.05956 ABIN1995476 FACS FITC Mouse IgG1 AA 2-118 Log in to see 04
14.05956 ABIN5506811 FACS Mouse IgG1 AA 2-118 Log in to see 04
1 ABIN656558 FACS IHC (p) WB Rabbit Ig AA 31-61, Center Log in to see Polyclonal 2
1 ABIN354772 FACS IF IHC (p) WB Rabbit IgG pThr37, pThr46 Log in to see
1 ABIN603974 FACS WB Biotin Rabbit IgG pThr37, pThr46 Log in to see
1 ABIN229451 FACS ELISA WB Rabbit IgG pThr46 Log in to see
1 ABIN5611114 ELISA FACS ICC IHC Mouse IgG1 pSer65 Log in to see 1E2E7
1 ABIN5611115 ELISA FACS IHC Mouse IgG1 pSer65 Log in to see 2D1G11
1 ABIN2258727 FACS IHC ELISA WB Rabbit IgG AA 38-69, Center, Internal Region Log in to see Polyclonal
1 ABIN1813773 FACS IHC (p) WB Rabbit AA 31-61 Log in to see Polyclonal
1 ABIN5624283 FACS FITC Rabbit IgG1 kappa pThr37, pThr46 Log in to see 4EB1T37T46-A5
1 ABIN5624282 FACS WB Rabbit IgG1 kappa pThr37, pThr46 Log in to see 4EB1T37T46-A5
1 ABIN2797839 FACS IHC WB Rabbit Ig Fraction Center Log in to see Polyclonal

General

Antigen Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Antibodies
Epitope AA 2-118
(61), (36), (29), (29), (27), (22), (19), (16), (15), (15), (15), (15), (14), (12), (12), (8), (8), (7), (6), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(461), (278), (236), (20), (17), (13), (9), (5), (5), (5), (3), (2), (2), (1), (1), (1), (1), (1)
Host Mouse
(402), (96), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This EIF4EBP1 antibody is conjugated to PE
(19), (17), (11), (9), (8), (8), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(346), (216), (201), (111), (66), (30), (17), (17), (14), (8), (7), (6), (5), (4), (3), (1)
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Product Details anti-EIF4EBP1 Antibody

Target Details EIF4EBP1 Application Details Handling Images
Specificity Human 4E-BP1 / EIF4EBP1
Characteristics This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human 4E-BP1 / EIF4EBP1 (rh 4E-BP1 / EIF4EBP1, ABIN2001935 NP_004086.1, Ser2-Ile118, and conjugated with PE under optimum conditions, the unreacted PE was removed.
Immunogen Recombinant Human 4E-BP1 / EIF4EBP1 protein (ABIN2001935)
Clone 04
Isotype IgG1

Target Details EIF4EBP1

Product Details anti-EIF4EBP1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name EIF4EBP1 (EIF4EBP1 Antibody Abstract)
Background Eukaryotic translation initiation factor 4E-binding protein 1, also known as Phosphorylated heat- and acid-stable protein regulated by insulin 1, 4E-BP1, eIF4E-binding protein 1 and EIF4EBP1, belongs to theeIF4E-binding protein family. EIF4EBP1 / 4E-BP1 regulates eIF4E activity by preventing its assembly into the eIF4F complex. It mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. Nonphosphorylated EIF4EBP1 / 4E-BP1 competes with EIF4G1/EIF4G3 to interact with EIF4E. Insulin stimulated MAP-kinase (MAPK1 and MAPK3) or mTORC1 phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind and consequent initiation of translation. It interacts with RPTOR as well. Endoplasmic reticulum (ER) stress-mediated apoptosis may play a crucial role in loss of pancreatic beta cell mass, contributing to the development of diabetes. Induction of EIF4EBP1 / 4E-BP1, the suppressor of the mRNA 5' cap-binding protein eukaryotic initiation factor 4E (eIF4E), is involved in beta cell survival under ER stress. EIF4EBP1 / 4E-BP1 induction contributes to the maintenance of beta cell homeostasis during ER stress and is a potential therapeutic target for diabetes.
NCBI Accession NP_004086.1
Pathways MAPK Signaling, PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Cell Size

Application Details

Product Details anti-EIF4EBP1 Antibody Target Details EIF4EBP1 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-EIF4EBP1 Antibody Target Details EIF4EBP1 Application Details Images back to top
Format Liquid
Concentration 0.1 mg/mL
Buffer Aqueous solution containing 0.5 % BSA and 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal
Storage 4 °C
Storage Comment This antibody is stable for 12 months from date of receipt when stored at 2°C-8°C. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Expiry Date 12 months

Images

Product Details anti-EIF4EBP1 Antibody Target Details EIF4EBP1 Application Details Handling back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 2-118) antibody (PE) (ABIN1995478) Profile of anti-4EBP1 reactivity on HepG2 cells analyzed by flow cytometry.