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anti-Human EIF4EBP1 antibody for Flow Cytometry

Recommended EIF4EBP1 Antibody (supplied by: Log in to see )

Antigen
Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Antibodies
  • 4e-bp
  • 4E-BP
  • 4e-bp1
  • 4E-BP1
  • 4ebp
  • 4eBP
  • 4EBP
  • 4EBP1
  • 43-BP
  • 153432_at
  • AA959816
  • anon-WO0172774.158
  • BcDNA.HL08053
  • BcDNA:HL08053
  • BP-1
  • CG8846
  • CT8705
  • d4e-bp
  • d4E-BP
  • d4E-BP1
  • d4EBP
  • d4eBP
  • Dm 4E-BP
  • Dmel\\CG8846
  • dthor
  • eIF4E-BP
  • EIF4EBP1
  • fc04h09
  • l(2)06270
  • l(2)k07736
  • l(2)k13517
  • PHAS-I
  • Phas1
  • pp20
  • thor
  • Thor/EIF4EBP
  • wu:fc04h09
  • zgc:64137
Epitope
AA 2-118
59
30
29
22
21
20
17
14
14
13
13
13
12
12
11
10
9
8
8
6
5
5
5
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
438
240
192
11
8
5
2
2
1
1
1
Host
Mouse
386
91
9
Clonality
Monoclonal
Conjugate
This EIF4EBP1 antibody is conjugated to FITC
20
16
12
11
8
8
5
5
5
5
5
5
5
5
5
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
317
202
193
89
56
27
20
18
15
7
5
4
4
3
3
1
Supplier
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Catalog No. ABIN1995476
$ 198.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.30226976 ABIN1995478 FACS PE Mouse IgG1 AA 2-118 Log in to see 4
0.30226976 ABIN2160874 FACS IHC WB Rabbit Ig Fraction Center Log in to see Polyclonal
0.30226976 ABIN2677045 FACS ICS EFluor 660 Mouse IgG2b kappa pThr36, pThr45 Log in to see V3NTY24
0.0010482287 ABIN656558 FACS IHC (p) WB Rabbit Ig AA 31-61, Center Log in to see Polyclonal 2
0.0010482287 ABIN189001 FACS IHC (p) IP IHC WB Rabbit IgG C-Term Log in to see Y330 1
0.0010482287 ABIN603974 FACS WB Biotin Rabbit IgG Thr37, Thr46 Log in to see
0.0010482287 ABIN229451 FACS ELISA WB Rabbit IgG Thr46 Log in to see
0.0010482287 ABIN1813773 FACS IHC (p) WB Rabbit AA 38-69 Log in to see Polyclonal
0.0010482287 ABIN2258727 FACS IHC ELISA WB Rabbit IgG AA 38-69, Center, Internal Region Log in to see Polyclonal
0.0010482287 ABIN2797839 FACS IHC WB Rabbit Ig Fraction Center Log in to see Polyclonal
0.0010482287 ABIN3014095 FACS PE Mouse IgG2b kappa pThr36, pThr45 Log in to see V3NTY24

Top referenced anti-EIF4EBP1 antibody for Flow Cytometry

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General

Antigen Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Antibodies
Epitope AA 2-118
(59), (30), (29), (22), (21), (20), (17), (14), (14), (13), (13), (13), (12), (12), (11), (10), (9), (8), (8), (6), (5), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(438), (240), (192), (11), (8), (5), (2), (2), (1), (1), (1)
Host Mouse
(386), (91), (9)
Clonality (Clone)
Monoclonal   ( )
Conjugate This EIF4EBP1 antibody is conjugated to FITC
(20), (16), (12), (11), (8), (8), (5), (5), (5), (5), (5), (5), (5), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(317), (202), (193), (89), (56), (27), (20), (18), (15), (7), (5), (4), (4), (3), (3), (1)
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Product Details anti-EIF4EBP1 Antibody

Target Details EIF4EBP1 Application Details Handling Images
Specificity Human 4E-BP1 / EIF4EBP1
Characteristics This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human 4E-BP1 / EIF4EBP1 (rh 4E-BP1 / EIF4EBP1, NP_004086.1, Ser2- Ile118) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Purification Affinity Purified
Immunogen Recombinant Human 4E-BP1 / EIF4EBP1 protein
Clone 4
Isotype IgG1

Target Details EIF4EBP1

Product Details anti-EIF4EBP1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name EIF4EBP1 (EIF4EBP1 Antibody Abstract)
Background Eukaryotic translation initiation factor 4E-binding protein 1, also known as Phosphorylated heat- and acid-stable protein regulated by insulin 1, 4E-BP1, eIF4E-binding protein 1 and EIF4EBP1, belongs to theeIF4E-binding protein family. EIF4EBP1 / 4E-BP1 regulates eIF4E activity by preventing its assembly into the eIF4F complex. It mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. Nonphosphorylated EIF4EBP1 / 4E-BP1 competes with EIF4G1/EIF4G3 to interact with EIF4E. Insulin stimulated MAP-kinase (MAPK1 and MAPK3) or mTORC1 phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind and consequent initiation of translation. It interacts with RPTOR as well. Endoplasmic reticulum (ER) stress-mediated apoptosis may play a crucial role in loss of pancreatic beta cell mass, contributing to the development of diabetes. Induction of EIF4EBP1 / 4E-BP1, the suppressor of the mRNA 5' cap-binding protein eukaryotic initiation factor 4E (eIF4E), is involved in beta cell survival under ER stress. EIF4EBP1 / 4E-BP1 induction contributes to the maintenance of beta cell homeostasis during ER stress and is a potential therapeutic target for diabetes.
NCBI Accession NP_004086.1
Pathways MAPK Signaling, PI3K-Akt Signaling, RTK Signaling, AMPK Signaling

Application Details

Product Details anti-EIF4EBP1 Antibody Target Details EIF4EBP1 Handling Images back to top
Application Notes Concentration: 2 μl/Test, 0.1 mg/ml
Restrictions For Research Use only

Handling

Product Details anti-EIF4EBP1 Antibody Target Details EIF4EBP1 Application Details Images back to top
Format Liquid
Buffer Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Handling Advice Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal
Storage 4 °C
Storage Comment This antibody is stable for 12 months from date of receipt when stored at 2 °C-8 °C.
Expiry Date 12 months

Images

Product Details anti-EIF4EBP1 Antibody Target Details EIF4EBP1 Application Details Handling back to top
Supplier Images
Flow Cytometry (FACS) image for anti-EIF4EBP1 antibody (Eukaryotic Translation Initiation Factor 4E Binding Protein 1) (AA 2-118) (FITC) (ABIN1995476) Profile of anti-4EBP1 reactivity on HepG2 cells analyzed by flow cytometry.