anti-Human GTPase NRas antibody for Enzyme Immunoassay

Recommended GTPase NRas Antibody (supplied by: Log in to see )

Antigen
GTPase NRas (NRAS) Antibodies
  • NRAS
  • AV095280
  • N-ras
  • ALPS4
  • NRAS1
  • NS6
  • N-RAS
  • fj99a10
  • wu:fj99a10
  • zgc:100761
  • zras-b1
  • H-RAS
  • HRAS
  • GTPase NRas
  • African clawed frog N-ras
  • neuroblastoma ras oncogene
  • neuroblastoma RAS viral (v-ras) oncogene homolog
  • Tsp_01117
  • n-ras
  • Nras
  • NRAS
  • nras
Reactivity
Human
101
28
18
6
3
3
2
2
2
2
2
1
Host
Mouse
44
37
20
Clonality
Monoclonal
Conjugate
This GTPase NRas antibody is un-conjugated
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
88
59
29
23
21
20
18
4
2
1
1
1
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Available images

Catalog No. ABIN781533
$ 412.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5552261 EIA FACS IF WB Rabbit Ig Fraction N-Term Log in to see Polyclonal
1 ABIN5552262 EIA IHC (p) WB Rabbit Ig Fraction C-Term Log in to see Polyclonal
1 ABIN372821 EIA IHC (p) WB Goat IgG Internal Region Log in to see Polyclonal
1 ABIN2727604 EIA IHC (p) WB Rabbit IgG Log in to see Polyclonal

General

Antigen GTPase NRas (NRAS) Antibodies
Reactivity Human
(101), (28), (18), (6), (3), (3), (2), (2), (2), (2), (2), (1)
Host Mouse
(44), (37), (20)
Clonality (Clone)
Monoclonal   ( )
Conjugate This GTPase NRas antibody is un-conjugated
(2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(88), (59), (29), (23), (21), (20), (18), (4), (2), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-GTPase NRas Antibody

Target Details GTPase NRas Application Details Handling ProductDetails: References for anti-GTPase NRas antibody (ABIN781533) Images
Specificity The antibody recognizes human RAS. Other species not tested.
Purification Protein-G affinity chromatography
Clone AT2G9
Isotype IgG2a

Target Details GTPase NRas

Product Details anti-GTPase NRas Antibody Application Details Handling ProductDetails: References for anti-GTPase NRas antibody (ABIN781533) Images back to top
Antigen
Alternative Name NRAS (NRAS Antibody Abstract)
Background The Ras protein is a subfamily of small GTPases that are involved in signal transduction. They are activated by ligand-binding receptor tyrosine kinases such as EGFR, PDGFR, CSF and FGF. These kinases transiently convert RAS-GDP (inactive form) to RAS-GTP, the active form of RAS. The main genes are HRAS, NRAS and KRAS.Synonyms: HRAS, HRAS1, KRAS, KRAS2, NRAS, RASK2
Gene ID 4893
Research Area Cancer
Pathways p53 Signaling, MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity

Application Details

Product Details anti-GTPase NRas Antibody Target Details GTPase NRas Handling ProductDetails: References for anti-GTPase NRas antibody (ABIN781533) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-GTPase NRas Antibody Target Details GTPase NRas Application Details ProductDetails: References for anti-GTPase NRas antibody (ABIN781533) Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, containing 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

ProductDetails: References for anti-GTPase NRas antibody (ABIN781533)

Product Details anti-GTPase NRas Antibody Target Details GTPase NRas Application Details Handling Images back to top
Background publications

Rotblat, Ehrlich, Haklai, Kloog: "The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer." in: Methods in enzymology, Vol. 439, pp. 467-89, 2008

Rocks, Peyker, Bastiaens: "Spatio-temporal segregation of Ras signals: one ship, three anchors, many harbors." in: Current opinion in cell biology, Vol. 18, Issue 4, pp. 351-7, 2006

Wennerberg, Rossman, Der: "The Ras superfamily at a glance." in: Journal of cell science, Vol. 118, Issue Pt 5, pp. 843-6, 2005

Images

Product Details anti-GTPase NRas Antibody Target Details GTPase NRas Application Details Handling ProductDetails: References for anti-GTPase NRas antibody (ABIN781533) back to top
Supplier Images
Western Blotting (WB) image for anti-GTPase NRas (NRAS) antibody (ABIN781533) anti-GTPase NRas (NRAS) antibody
Western Blotting (WB) image for anti-GTPase NRas (NRAS) antibody (ABIN781533) anti-GTPase NRas (NRAS) antibody (Image 2)