You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human MAP3K5 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended MAP3K5 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Antibodies
  • 7420452D20Rik
  • ASK
  • ASK1
  • MAP3K5
  • MAPKKK5
  • MEKK5
  • Mekk5
  • mitogen-activated protein kinase kinase kinase 5
  • MUD21.11
  • MUD21_11
Epitope
AA 825-875, pThr845
52
47
43
23
22
19
17
15
13
12
12
9
8
6
5
4
4
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
364
136
77
4
1
Host
Rabbit
350
22
Clonality
Polyclonal
Conjugate
This MAP3K5 antibody is un-conjugated
13
13
12
7
7
7
5
5
5
5
5
5
5
5
5
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
277
147
132
54
49
37
20
11
6
6
6
2
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN683128
$ 291.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008851404 ABIN802038 IF (p) IHC (p) WB Rabbit IgG pSer83 Log in to see Polyclonal
0.0008851404 ABIN878558 IF (p) Alexa Fluor 647 Rabbit IgG AA 825-875, pThr845 Log in to see Polyclonal
0.0008851404 ABIN878561 IF (p) Alexa Fluor 350 Rabbit IgG AA 825-875, pThr845 Log in to see Polyclonal
0.0008851404 ABIN878557 IF (p) Alexa Fluor 488 Rabbit IgG AA 825-875, pThr845 Log in to see Polyclonal
0.0008851404 ABIN878559 IF (p) Alexa Fluor 555 Rabbit IgG AA 825-875, pThr845 Log in to see Polyclonal
0.0008851404 ABIN683131 IF (p) Cy3 Rabbit IgG AA 825-875, pThr845 Log in to see Polyclonal
0.0008851404 ABIN683132 IF (p) Cy5 Rabbit IgG AA 825-875, pThr845 Log in to see Polyclonal
0.0008851404 ABIN683133 IF (p) Cy5.5 Rabbit IgG AA 825-875, pThr845 Log in to see Polyclonal
0.0008851404 ABIN683135 IF (p) FITC Rabbit IgG AA 825-875, pThr845 Log in to see Polyclonal
0.0008851404 ABIN683134 IF (p) Cy7 Rabbit IgG AA 825-875, pThr845 Log in to see Polyclonal
0.0008851404 ABIN2809992 IF (p) Alexa Fluor 594 Rabbit IgG AA 825-875, pThr845 Log in to see Polyclonal
0.0008851404 ABIN802044 IF (p) Cy7 Rabbit IgG pSer83 Log in to see Polyclonal
0.0008851404 ABIN802042 IF (p) Cy5 Rabbit IgG pSer83 Log in to see Polyclonal
0.0008851404 ABIN802056 IF (p) Cy3 Rabbit IgG pSer1033 Log in to see Polyclonal
0.0008851404 ABIN802057 IF (p) Cy5 Rabbit IgG pSer1033 Log in to see Polyclonal
0.0008851404 ABIN802060 IF (p) FITC Rabbit IgG pSer1033 Log in to see Polyclonal
0.0008851404 ABIN802045 IF (p) FITC Rabbit IgG pSer83 Log in to see Polyclonal
0.0008851404 ABIN802043 IF (p) Cy5.5 Rabbit IgG pSer83 Log in to see Polyclonal
0.0008851404 ABIN802058 IF (p) Cy5.5 Rabbit IgG pSer1033 Log in to see Polyclonal
0.0008851404 ABIN802041 IF (p) Cy3 Rabbit IgG pSer83 Log in to see Polyclonal

Top referenced anti-MAP3K5 antibody for Immunofluorescence (Paraffin-embedded Sections)

Similar anti-MAP3K5 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 23 Antibodies 128 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies 11 Antibodies
Flow Cytometry (FACS) 1 Antibodies 7 Antibodies
Immunocytochemistry (ICC) 9 Antibodies 20 Antibodies
Immunofluorescence (IF) 12 Antibodies 38 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 44 Antibodies 55 Antibodies
Immunohistochemistry (IHC) 43 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 25 Antibodies
Western Blotting (WB) 78 Antibodies
Immunochromatography (IC) 2 Antibodies

General

Antigen Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Antibodies
Epitope AA 825-875, pThr845
(52), (47), (43), (23), (22), (19), (17), (15), (13), (12), (12), (9), (8), (6), (5), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(364), (136), (77), (4), (1)
Host Rabbit
(350), (22)
Clonality
Polyclonal
Conjugate This MAP3K5 antibody is un-conjugated
(13), (13), (12), (7), (7), (7), (5), (5), (5), (5), (5), (5), (5), (5), (5)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(277), (147), (132), (54), (49), (37), (20), (11), (6), (6), (6), (2), (1), (1), (1)
Pubmed 1 reference available
Supplier Log in to see

Product Details anti-MAP3K5 Antibody

Target Details MAP3K5 Application Details Handling References for anti-MAP3K5 Antibody (ABIN683128) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from mouse ASK1 around the phosphorylation site of Thr845
Isotype IgG

Target Details MAP3K5

Product Details anti-MAP3K5 Antibody Application Details Handling References for anti-MAP3K5 Antibody (ABIN683128) Images back to top
Antigen
Alternative Name Ask1 (MAP3K5 Antibody Abstract)
Background

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival. Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation. MAP3K5/ASK1 is required for the innate immune response, which is essential for host defense against a wide range of pathogens. Mediates signal transduction of various stressors like oxidative stress as well as by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF) or lipopolysaccharide (LPS). Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K4/SEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. These MAP2Ks in turn activate p38 MAPKs and c-jun N-terminal kinases (JNKs). Both p38 MAPK and JNKs control the transcription factors activator protein-1 (AP-1).

Subcellular location: Cytoplasm


Synonyms: ASK, ASK1, Mekk5, MAPKKK5, 742452D2Rik, Mitogen-activated protein kinase kinase kinase 5, Apoptosis signal-regulating kinase 1, ASK-1, MAPK/ERK kinase kinase 5, MEK kinase 5, MEKK 5, Map3k5
Gene ID 26408
UniProt O35099
Research Area Cardiovascular, Hypertrophy, Apoptosis/Necrosis
Pathways MAPK Signaling

Application Details

Product Details anti-MAP3K5 Antibody Target Details MAP3K5 Handling References for anti-MAP3K5 Antibody (ABIN683128) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-MAP3K5 Antibody Target Details MAP3K5 Application Details References for anti-MAP3K5 Antibody (ABIN683128) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-MAP3K5 Antibody (ABIN683128)

Product Details anti-MAP3K5 Antibody Target Details MAP3K5 Application Details Handling Images back to top
Product cited in:

Taniuchi, Furihata, Hanazaki, Iwasaki, Tanaka, Shimizu, Saito, Saibara: "Peroxiredoxin 1 Promotes Pancreatic Cancer Cell Invasion by Modulating p38 MAPK Activity." in: Pancreas, Vol. 44, Issue 2, pp. 331-40, 2015

Images

Product Details anti-MAP3K5 Antibody Target Details MAP3K5 Application Details Handling References for anti-MAP3K5 Antibody (ABIN683128) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-MAP3K5 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 5) (AA 825-875) (ABIN683128) Formalin-fixed and paraffin embedded rat heart tissue labeled with Anti-phospho-ASK1(...
SDS-PAGE (SDS) image for anti-MAP3K5 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 5) (AA 825-875) (ABIN683128) L1 rat heart, L2 rat brain lysates probed (ABIN683128) at 1:200 in 4 °C. Followed by ...