anti-Mouse (Murine) MAP3K5 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MAP3K5 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Antibodies
  • 7420452D20Rik
  • ASK
  • ASK1
  • MAPKKK5
  • Mekk5
  • mitogen-activated protein kinase kinase kinase 5
  • MUD21.11
  • MUD21_11
  • MEKK5
  • MAP3K5
  • mitogen-activated protein kinase kinase kinase 5
  • Map3k5
  • MAPKKK5
  • MAP3K5
Epitope
AA 825-875, pThr845
57
46
37
19
19
18
15
14
14
14
11
10
6
6
5
5
4
4
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
369
169
96
6
1
1
1
1
1
1
Host
Rabbit
350
25
Clonality
Polyclonal
Conjugate
This MAP3K5 antibody is un-conjugated
12
12
11
6
6
6
5
5
5
5
5
5
5
5
5
5
5
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
277
145
121
68
64
40
20
10
10
9
4
3
2
1
1
Options
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Catalog No. ABIN683128
$ 329.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.776815 ABIN498823 IHC (p) Rabbit pSer966 Log in to see Polyclonal
13.776815 ABIN498913 IHC (p) Rabbit Log in to see Polyclonal
13.776815 ABIN461898 IHC (p) ELISA WB Rabbit N-Term Log in to see Polyclonal
13.776815 ABIN461897 ICC IHC (p) ELISA WB Rabbit C-Term Log in to see Polyclonal
13.776815 ABIN4281872 IHC IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN196914 IHC (p) WB Rabbit pSer966 Log in to see Polyclonal 4
1 ABIN197326 IF IHC (p) WB Rabbit Ser966 Log in to see Polyclonal 4
1 ABIN265316 EIA IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN317962 IHC (p) WB Rabbit pSer966 Log in to see Polyclonal
1 ABIN4281869 ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN658363 IHC (p) WB Rabbit Ig AA 1175-1203, C-Term Log in to see Polyclonal
1 ABIN2888359 IHC (p) ELISA WB Rabbit IgG pSer966 Log in to see Polyclonal
1 ABIN4281878 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN683137 IHC (p) WB HRP Rabbit IgG AA 825-875, pThr845 Log in to see Polyclonal
1 ABIN1736718 ICC IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1736719 IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN802062 IHC (p) WB HRP Rabbit IgG pSer1033 Log in to see Polyclonal
1 ABIN682807 IHC (p) WB HRP Rabbit IgG pSer966 Log in to see Polyclonal
1 ABIN683130 IHC (p) WB Biotin Rabbit IgG AA 825-875, pThr845 Log in to see Polyclonal
1 ABIN683107 IHC (p) WB HRP Rabbit IgG pSer967 Log in to see Polyclonal

Top referenced anti-MAP3K5 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-MAP3K5 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 32 Antibodies 117 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies 10 Antibodies
Immunocytochemistry (ICC) 9 Antibodies 19 Antibodies
Immunofluorescence (IF) 12 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 52 Antibodies
Immunohistochemistry (IHC) 54 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 36 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 102 Antibodies
Flow Cytometry (FACS) 9 Antibodies
Immunochromatography (IC) 2 Antibodies

General

Antigen Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Antibodies
Epitope AA 825-875, pThr845
(57), (46), (37), (19), (19), (18), (15), (14), (14), (14), (11), (10), (6), (6), (5), (5), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(369), (169), (96), (6), (1), (1), (1), (1), (1), (1)
Host Rabbit
(350), (25)
Clonality
Polyclonal
Conjugate This MAP3K5 antibody is un-conjugated
(12), (12), (11), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(277), (145), (121), (68), (64), (40), (20), (10), (10), (9), (4), (3), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-MAP3K5 Antibody

Target Details MAP3K5 Application Details Handling ProductDetails: References for anti-MAP3K5 antibody (ABIN683128) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from mouse ASK1 around the phosphorylation site of Thr845
Isotype IgG

Target Details MAP3K5

Product Details anti-MAP3K5 Antibody Application Details Handling ProductDetails: References for anti-MAP3K5 antibody (ABIN683128) Images back to top
Antigen
Alternative Name Ask1 (MAP3K5 Antibody Abstract)
Background

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival. Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation. MAP3K5/ASK1 is required for the innate immune response, which is essential for host defense against a wide range of pathogens. Mediates signal transduction of various stressors like oxidative stress as well as by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF) or lipopolysaccharide (LPS). Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K4/SEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. These MAP2Ks in turn activate p38 MAPKs and c-jun N-terminal kinases (JNKs). Both p38 MAPK and JNKs control the transcription factors activator protein-1 (AP-1).

Subcellular location: Cytoplasm


Synonyms: ASK, ASK1, Mekk5, MAPKKK5, 742452D2Rik, Mitogen-activated protein kinase kinase kinase 5, Apoptosis signal-regulating kinase 1, ASK-1, MAPK/ERK kinase kinase 5, MEK kinase 5, MEKK 5, Map3k5
Gene ID 26408
UniProt O35099
Research Area Cardiovascular, Hypertrophy, Apoptosis/Necrosis
Pathways MAPK Signaling, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-MAP3K5 Antibody Target Details MAP3K5 Handling ProductDetails: References for anti-MAP3K5 antibody (ABIN683128) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-MAP3K5 Antibody Target Details MAP3K5 Application Details ProductDetails: References for anti-MAP3K5 antibody (ABIN683128) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-MAP3K5 antibody (ABIN683128)

Product Details anti-MAP3K5 Antibody Target Details MAP3K5 Application Details Handling Images back to top
Product cited in:

Taniuchi, Furihata, Hanazaki, Iwasaki, Tanaka, Shimizu, Saito, Saibara: "Peroxiredoxin 1 Promotes Pancreatic Cancer Cell Invasion by Modulating p38 MAPK Activity." in: Pancreas, Vol. 44, Issue 2, pp. 331-40, 2015

Images

Product Details anti-MAP3K5 Antibody Target Details MAP3K5 Application Details Handling ProductDetails: References for anti-MAP3K5 antibody (ABIN683128) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-MAP3K5 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 5) (AA 825-875) (ABIN683128) Formalin-fixed and paraffin embedded rat heart tissue labeled with Anti-phospho-ASK1(...
SDS-PAGE (SDS) image for anti-MAP3K5 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 5) (AA 825-875) (ABIN683128) L1 rat heart, L2 rat brain lysates probed (ABIN683128) at 1:200 in 4 °C. Followed by ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-MAP3K5 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 5) (AA 825-875) (ABIN683128) Formalin-fixed and paraffin embedded rat heart tissue labeled with Anti-phospho-ASK1(...