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Browse our anti-PAK1 (PAK1) Antibodies

Full name:
anti-P21-Activated Kinase 1 Antibodies (PAK1)
On www.antibodies-online.com are 337 P21-Activated Kinase 1 (PAK1) Antibodies from 29 different suppliers available. Additionally we are shipping PAK1 Proteins (15) and PAK1 Kits (12) and many more products for this protein. A total of 378 PAK1 products are currently listed.
Synonyms:
AW045634, pak, PAK-1, Paka, PAKalpha, X-PAK1, XPak1
list all antibodies Gene Name GeneID UniProt
PAK1 5058 Q13153
PAK1 18479  
PAK1 29431 P35465

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Top referenced anti-PAK1 Antibodies

  1. Human Polyclonal PAK1 Primary Antibody for EIA - ABIN358296 : Li, Guan: The Down syndrome cell adhesion molecule (DSCAM) interacts with and activates Pak. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN358296

  2. Human Polyclonal PAK1 Primary Antibody for EIA - ABIN358352 : DerMardirossian, Schnelzer, Bokoch: Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase. in Molecular cell 2004 (PubMed)
    Show all 5 references for ABIN358352

  3. Human Polyclonal PAK1 Primary Antibody for IF, IHC (p) - ABIN196896 : Parsons, Monypenny, Ameer-Beg, Millard, Machesky, Peter, Keppler, Schiavo, Watson, Chernoff, Zicha, Vojnovic, Ng: Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells. in Molecular and cellular biology 2005 (PubMed)
    Show all 4 references for ABIN196896

  4. Human Polyclonal PAK1 Primary Antibody for WB - ABIN1944750 : Brown, Stowers, Baer, Trejo, Coughlin, Chant: Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway. in Current biology : CB 1997 (PubMed)
    Show all 3 references for ABIN1944750

  5. Human Polyclonal PAK1 Primary Antibody for EIA, IHC (p) - ABIN360317 : Chen, Yin, Zhu, Yan, Ji, Chen, Cai, Zhang, Zong, Hu, Yuan, Shen, Gu: The C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase 1 and inhibits its activity during anoikis. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for ABIN360317

  6. Dog (Canine) Polyclonal PAK1 Primary Antibody for WB - ABIN374720 : Zhao, Ma, Calon, Harris-White, Yang, Lim, Morihara, Ubeda, Ambegaokar, Hansen, Weisbart, Teter, Frautschy, Cole: Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease. in Nature neuroscience 2006 (PubMed)

  7. Human Polyclonal PAK1 Primary Antibody for DB, IF - ABIN389799 : El-Baba, Mahadevan, Fahlbusch, S, Rau, Gali-Muhtasib, Schneider-Stock: Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer. in Molecular cancer 2014 (PubMed)

More Antibodies against PAK1 Interaction Partners

Xenopus laevis P21-Activated Kinase 1 (PAK1) interaction partners

  1. results represent the first evidence that Pak1 links extracellular signals to the genetic cascade of transcription factors necessary for cranial neural crest specification

  2. These findings expand the role of phosphoinositides in kinase signaling and suggest how altered phosphoinositide metabolism may upregulate Pak1 activity in cancer cells.

  3. The data suggest that EphA4 activation sequesters active Cdc42 (show CDC42 Antibodies) and in this way down-regulates cell-cell adhesion.

  4. Pak1 inhibition interferes with the guidance of mesendoderm migration by directional cues residing in the extracellular matrix of the blastocoel roof, and with mesendoderm translocation in the embryo.

Human P21-Activated Kinase 1 (PAK1) interaction partners

  1. p120 (show HNRNPU Antibodies) participates in the progress of gastric cancer through regulating Rac1 and Pak1.

  2. The role of PAK1 in cancer drug resistance in BRAF (show BRAF Antibodies)-mutated cancer

  3. High p21-activated kinase 1 and cell division control protein 42 homolog (show CDC42 Antibodies) expressions are closely related to the clinicopathological features and poor prognosis of cervical carcinoma, serving as unfavorable prognostic factors.

  4. miR7 (show LILRB1 Antibodies) negatively regulates PAK1 protein expression but has no effect on PAK1 mRNA expression. Knockdown of PAK1 expression markedly suppressed thyroid cancer cell proliferation, migration and invasion.

  5. VEGF (show VEGFA Antibodies)-induced angiogenesis and vascular permeability are inhibited by BET bromodomain suppression through blocking of VEGFR2 (show KDR Antibodies)-mediated activation of PAK1 and eNOS (show NOS3 Antibodies)

  6. Myricetin effectively suppressed the protein expression of p21-activated kinase 1 (PAK1).

  7. overexpression of PAK1, NEK6 (show NEK6 Antibodies), AURKA (show AURKA Antibodies), and AURKB (show AURKB Antibodies) genes in patients with Colorectal adenomatous polyp and colorectal cancer in the Turkish population.

  8. Pak1 expression is not associated with breast cancer recurrence and resistance to tamoxifen.

  9. 1alpha,25-Dihydroxy-Vitamin D3 leads to disruption of RAC1 and PAK1 activity with subsequent actin depolymerization of endometrial carcinoma cells.

  10. Study acts as a further supplement of the genetic features of neuroendocrine tumors. Somatic mutations of three potential tumor-related genes (HRAS (show HRAS Antibodies), PAK1 and MEN1 (show MEN1 Antibodies)) might contribute to the tumorigenesis of thymic neuroendocrine tumors with EAS.

Mouse (Murine) P21-Activated Kinase 1 (PAK1) interaction partners

  1. These results implicate PAK1 as a regulator of Pancreatic stellate cells activation, proliferation and apoptosis. Targeting stromal PAK1 could increase therapeutic response and survival of patients with pancreatic cancer.

  2. The authors conclude that PAK1, besides its role in virus entry, also plays a relevant role in vaccinia virus dissemination.

  3. PAK1 contributes to initiation of intestinal carcinogenesis

  4. Pak1 is essential for adaptive physiological exercise-induced cardiac remodelling and support previous evidence that demonstrates Pak1 signalling is important for cardiac growth and survival.

  5. Further investigations identified Pak1-ERM (show ETV5 Antibodies) as a downstream signaling cascade upon Rac1 activation in the luminal epithelium necessary for uterine receptivity...Rac1 via P38 MAPK (show MAPK14 Antibodies) signaling ensures timely epithelial apoptotic death at postimplantation.

  6. Nischarin (show NISCH Antibodies) inhibits neurite outgrowth by blocking PAK1 activation in neurons.

  7. results indicate that NCAM (show NCAM1 Antibodies) is delivered to the cell surface through a kinesin-1-mediated transport mechanism in a PAK1-dependent manner.

  8. propose that by repressing Pak1 expression, Rb prevents Rac1 hyperactivity usually associated with cancer and related to cytoskeletal derangements that disrupt cell adhesion, consequently enhancing cancer cell migratory capacity

  9. Pak1 is an important factor in the initiation and progression of atherogenesis.

  10. miR (show MLXIP Antibodies)-155 regulates the delicate balance between PAK1-mediated proliferation and apoptosis in T cells impacting lymphoid organ size and function.

Caenorhabditis elegans (C. elegans) P21-Activated Kinase 1 (PAK1) interaction partners

  1. FOXO-Pak1 pathway was recently shown to regulate mammalian neuronal polarity, our findings indicate that the roles of FOXO and Pak1 in neuronal migration are most likely conserved from C. elegans to higher organisms.

  2. PAK1 promotes reproduction, whereas it inactivates HSP16.2 gene and shortens lifespan.

  3. Pak-1 interacts with Wnt (show WNT2 Antibodies) signaling to regulate tissue polarity and gene expression.

  4. only PAK-1 functions in the GIT/PIX (show ARHGEF7 Antibodies)/PAK pathway independently of RAC (show AKT1 Antibodies)/CDC42 (show CDC42 Antibodies) GTPases.

  5. Data show that combined loss of ROCK and PAK, or ROCK and MRCK (show CDC42BPA Antibodies), completely prevented embryonic elongation, but a constitutively active form of MLC-4 could only rescue a lack of MRCK (show CDC42BPA Antibodies).

PAK1 Antigen Profile

Antigen Summary

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with PAK1

  • p21 protein (Cdc42/Rac)-activated kinase 1 (pak1) antibody
  • p21 protein (Cdc42/Rac)-activated kinase 1 (PAK1) antibody
  • p21 protein (Cdc42/Rac)-activated kinase 1 (Pak1) antibody
  • Protein PAK-1 (pak-1) antibody
  • AW045634 antibody
  • pak antibody
  • PAK-1 antibody
  • Paka antibody
  • PAKalpha antibody
  • X-PAK1 antibody
  • XPak1 antibody

Protein level used designations for PAK1

p21 GTPase-associated kinase 1 , p21-activated kinase 1 , p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) , putative CDKN1A-activated kinase 1 , STE20 homolog, yeast , alpha-PAK , p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) , p65-PAK , serine/threonine-protein kinase PAK 1 , CDC42/RAC effector kinase PAK-A , activated protein kinase alpha , PAK-1 , p21 (CDKN1A)-activated kinase 1 , p68-PAK , protein kinase MUK2

GENE ID SPECIES
398126 Xenopus laevis
451439 Pan troglodytes
100190755 Taeniopygia guttata
5058 Homo sapiens
18479 Mus musculus
29431 Rattus norvegicus
607885 Canis lupus familiaris
533729 Bos taurus
180873 Caenorhabditis elegans
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