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anti-Human ROCK1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended ROCK1 Antibody (supplied by: Log in to see )

Antigen
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) Antibodies
  • 1110055K06Rik
  • CG9774
  • Dmel\\CG9774
  • DRhk
  • dRok
  • drok
  • Drok
  • DROK
  • DRok
  • dROK
  • LOC100229794
  • P160ROCK
  • P160Rock
  • p160ROCK
  • Rhk
  • RhoK
  • ROCK
  • Rock
  • ROCK-1
  • ROCK-I
  • Rock-I
  • ROCK1
  • ROK
  • Rok
  • ROKalpha/beta
Reactivity
Human, Mouse (Murine), Rat (Rattus)
142
97
93
21
19
19
3
3
2
2
1
Host
Rabbit
108
39
Clonality
Polyclonal
Conjugate
This ROCK1 antibody is un-conjugated
4
4
4
4
4
3
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
109
32
31
21
17
17
10
8
2
1
1
1
1
Supplier
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Catalog No. ABIN498550
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008982679 ABIN738636 IF (p) IHC (p) WB Rabbit IgG AA 980-1030 Log in to see Polyclonal 1
0.0008982679 ABIN707771 IF (p) IHC (p) WB Rabbit IgG pThr455, pSer456 Log in to see Polyclonal 2
0.0008982679 ABIN258448 ICC FACS IHC (fro) IF IHC (p) IP IHC WB Rabbit IgG C-Term Log in to see EP786Y
0.0008982679 ABIN152055 ICC IF IHC (p) IP IHC WB Rabbit IgG C-Term Log in to see Polyclonal 2
0.0008982679 ABIN959683 IHC (p) WB Rabbit N-Term Log in to see Polyclonal
0.0008982679 ABIN1104014 IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN738645 IHC (p) WB HRP Rabbit IgG AA 980-1030 Log in to see Polyclonal
0.0008982679 ABIN738638 IHC (p) WB Biotin Rabbit IgG AA 980-1030 Log in to see Polyclonal
0.0008982679 ABIN707773 IHC (p) WB Biotin Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
0.0008982679 ABIN707780 IHC (p) WB HRP Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
0.0008982679 ABIN1738918 IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
0.0008982679 ABIN1833758 ICC IHC (p) WB Rabbit AA 107-371 Log in to see Polyclonal
0.0008982679 ABIN2856887 ICC IF IP IHC (p) WB Rabbit N-Term Log in to see Polyclonal
0.0008982679 ABIN446984 IHC (p) IHC WB Rabbit Asp311 Log in to see Polyclonal
0.0008982679 ABIN2178927 IHC (p) WB Biotin Rabbit IgG pSer456, pThr455 Log in to see Polyclonal
0.0008982679 ABIN2178933 IHC (p) WB HRP Rabbit IgG pSer456, pThr455 Log in to see Polyclonal
0.0008982679 ABIN2178922 IF (p) IHC (p) WB Rabbit IgG pSer456, pThr455 Log in to see Polyclonal
0.0008982679 ABIN1738919 IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN2800511 IF (cc) IHC (f) IF IP IHC (p) IHC WB Rabbit IgG AA 107-371, N-Term Log in to see Polyclonal
0.0008982679 ABIN4350898 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-ROCK1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

  • Human Polyclonal ROCK1 Primary Antibody for IF (p), IHC (p) - ABIN707771 (2 Publications): Wang, Zhang, Wang, Zhang, Mao, Zhuang, Tang, Luo, Zhou, Zhang: Vascular endothelial growth factor stimulates endothelial differentiation from mesenchymal stem cells via Rho/myocardin-related transcription factor--a signaling pathway. in The international journal of biochemistry & cell biology 2013 (PubMed)

  • Human Polyclonal ROCK1 Primary Antibody for ICC, IF - ABIN152055 (2 Publications): Chang, Xie, Shah, Schneider, Entman, Wei, Schwartz: Activation of Rho-associated coiled-coil protein kinase 1 (ROCK-1) by caspase-3 cleavage plays an essential role in cardiac myocyte apoptosis. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

Similar anti-ROCK1 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 107 Antibodies 63 Antibodies 60 Antibodies
Immunoprecipitation (IP) 11 Antibodies 4 Antibodies 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 24 Antibodies 15 Antibodies 14 Antibodies
Immunohistochemistry (IHC) 19 Antibodies 9 Antibodies 8 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies 1 Antibodies 1 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 32 Antibodies 32 Antibodies

General

Antigen rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(142), (97), (93), (21), (19), (19), (3), (3), (2), (2), (1)
Host Rabbit
(108), (39)
Clonality
Polyclonal
Conjugate This ROCK1 antibody is un-conjugated
(4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(109), (32), (31), (21), (17), (17), (10), (8), (2), (1), (1), (1), (1)
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Product Details anti-ROCK1 Antibody

Target Details ROCK1 Application Details Handling Images
Specificity This antibody detects endogenous levels of Rock-1 protein. (region surrounding asn311)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography using epitope-specific immunogen
Purity > 95 % (by SDS-PAGE)

Target Details ROCK1

Product Details anti-ROCK1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name ROCK1 (ROCK1 Antibody Abstract)
Background Rho, the Ras-related small GTPase, is responsible for the regulation of Actinbased cytoskeletal structures including stress fibers, focal adhesions and the contractile RING apparatus. Rho proteins function as molecular switches that are able to turn cytokinesis on and off. Although little is known about signaling downstream of Rho, a host of putative Rho effector proteins have been described, including rhophilin, Rhotekin, citron and the serine/threonine kinase, protein kinase N. Two additional Rho-activated serine/threonine kinases have been described, designated Rock-1 and Rock-2 (also referred to as Roka) for Rho-associated coil-containing protein kinase. Rock-1 and Rock-2 share a structural similarity with myotonic dystrophy kinase.Synonyms: NY-REN-35, ROCK-1, Renal carcinoma antigen NY-REN-35, Rho-associated, Rho-associated protein kinase 1, coiled-coil-containing protein kinase 1, p160ROCK
Molecular Weight approx. 158 kDa
Gene ID 6093
NCBI Accession NP_005397
UniProt Q13464
Research Area Cancer, Cell Cycle, Cytoskeleton, Microfilaments, Apoptosis/Necrosis, Signaling
Pathways Microtubule Dynamics, WNT Signaling

Application Details

Product Details anti-ROCK1 Antibody Target Details ROCK1 Handling Images back to top
Application Notes Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-ROCK1 Antibody Target Details ROCK1 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-ROCK1 Antibody Target Details ROCK1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-ROCK1 antibody (rho-Associated, Coiled-Coil Containing Protein Kinase 1) (ABIN498550) Immunohistochemistry analyzes of Rock-1 antibody in paraffin-embedded human br...
Western Blotting (WB) image for anti-ROCK1 antibody (rho-Associated, Coiled-Coil Containing Protein Kinase 1) (ABIN498550) Western blot (WB) analysis of Rock-1 antibody in extracts from COS7 ...