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anti-Mouse (Murine) ROCK1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended ROCK1 Antibody (supplied by: Log in to see )

Antigen
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) Antibodies
  • LOC100229794
  • CG9774
  • DROK
  • DRhk
  • DRok
  • Dmel\\CG9774
  • Drok
  • ROCK
  • ROCK-1
  • ROCK1
  • ROK
  • ROKalpha/beta
  • Rhk
  • RhoK
  • Rock
  • Rok
  • dROK
  • dRok
  • drok
  • 1110055K06Rik
  • Rock-I
  • P160Rock
  • ROCK-I
  • P160ROCK
  • p160ROCK
  • Rho-associated, coiled-coil containing protein kinase 1
  • Rho-kinase
  • Rho-associated coiled-coil containing protein kinase 1
  • ROCK1
  • LOC100229794
  • rok
  • Rock1
  • rock1
Epitope
pThr455, pSer456
28
26
23
21
15
14
4
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
149
105
100
22
20
20
3
2
2
1
Host
Rabbit
111
41
Clonality
Polyclonal
Conjugate
This ROCK1 antibody is un-conjugated
5
4
4
4
4
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
108
35
32
31
25
21
20
12
2
1
1
1
1
1
Options
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Catalog No. ABIN707771
$ 329.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.0823965 ABIN738636 IF (p) IHC (p) WB Rabbit IgG AA 980-1030 Log in to see Polyclonal 1
12.0823965 ABIN498550 IHC (p) Rabbit Log in to see Polyclonal
12.0823965 ABIN4350898 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN152055 ICC IF IHC (p) IP IHC WB Rabbit IgG C-Term Log in to see Polyclonal 2
1 ABIN2856887 ICC IF IP IHC (p) WB Rabbit N-Term Log in to see Polyclonal
1 ABIN707780 IHC (p) WB HRP Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
1 ABIN738645 IHC (p) WB HRP Rabbit IgG AA 980-1030 Log in to see Polyclonal
1 ABIN707773 IHC (p) WB Biotin Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
1 ABIN738638 IHC (p) WB Biotin Rabbit IgG AA 980-1030 Log in to see Polyclonal
1 ABIN1738919 IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN2178933 IHC (p) WB HRP Rabbit IgG pSer456, pThr455 Log in to see Polyclonal
1 ABIN2178927 IHC (p) WB Biotin Rabbit IgG pSer456, pThr455 Log in to see Polyclonal
1 ABIN2178922 IF (p) IHC (p) WB Rabbit IgG pSer456, pThr455 Log in to see Polyclonal

Top referenced anti-ROCK1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

  • Human Polyclonal ROCK1 Primary Antibody for ICC, IF - ABIN152055 (2 Publications): Chang, Xie, Shah, Schneider, Entman, Wei, Schwartz: Activation of Rho-associated coiled-coil protein kinase 1 (ROCK-1) by caspase-3 cleavage plays an essential role in cardiac myocyte apoptosis. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

  • Human Polyclonal ROCK1 Primary Antibody for IF (p), IHC (p) - ABIN707771 (2 Publications): Wang, Zhang, Wang, Zhang, Mao, Zhuang, Tang, Luo, Zhou, Zhang: Vascular endothelial growth factor stimulates endothelial differentiation from mesenchymal stem cells via Rho/myocardin-related transcription factor--a signaling pathway. in The international journal of biochemistry & cell biology 2013 (PubMed)

Similar anti-ROCK1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 17 Antibodies 17 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 1 Antibodies
Flow Cytometry (FACS) 1 Antibodies 1 Antibodies
Immunochromatography (IC) 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 21 Antibodies 23 Antibodies
Immunofluorescence (IF) 24 Antibodies 24 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 36 Antibodies 36 Antibodies
Immunohistochemistry (IHC) 9 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 13 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Western Blotting (WB) 61 Antibodies

General

Antigen rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) Antibodies
Epitope pThr455, pSer456
(28), (26), (23), (21), (15), (14), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(149), (105), (100), (22), (20), (20), (3), (2), (2), (1)
Host Rabbit
(111), (41)
Clonality
Polyclonal
Conjugate This ROCK1 antibody is un-conjugated
(5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(108), (35), (32), (31), (25), (21), (20), (12), (2), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-ROCK1 Antibody

Target Details ROCK1 Application Details Handling References for anti-ROCK1 Antibody (ABIN707771) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human ROCK1 around the phosphorylation site of Thr455/Ser456
Isotype IgG

Target Details ROCK1

Product Details anti-ROCK1 Antibody Application Details Handling References for anti-ROCK1 Antibody (ABIN707771) Images back to top
Antigen
Alternative Name Rock1 (ROCK1 Antibody Abstract)
Background

Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress. Acts as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Required for centrosome positioning and centrosome-dependent exit from mitosis. Plays a role in terminal erythroid differentiation. May regulate closure of the eyelids and ventral body wall by inducing the assembly of actomyosin bundles. Promotes keratinocyte terminal differentiation. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization.


Synonyms: ROCK-I, P16ROCK, Rho-associated protein kinase 1, Renal carcinoma antigen NY-REN-35, Rho-associated, coiled-coil-containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase I, p16 ROCK-1, ROCK1
Gene ID 6093
UniProt Q13464
Research Area Cancer, Cell Cycle, Cytoskeleton, Microfilaments, Apoptosis/Necrosis, Signaling
Pathways Microtubule Dynamics, WNT Signaling

Application Details

Product Details anti-ROCK1 Antibody Target Details ROCK1 Handling References for anti-ROCK1 Antibody (ABIN707771) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-ROCK1 Antibody Target Details ROCK1 Application Details References for anti-ROCK1 Antibody (ABIN707771) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-ROCK1 Antibody (ABIN707771)

Product Details anti-ROCK1 Antibody Target Details ROCK1 Application Details Handling Images back to top
Product cited in:

Lin, Chang, Chen, Shih: "RhoA/ROCK1 regulates Avian Reovirus S1133-induced switch from autophagy to apoptosis." in: BMC veterinary research, Vol. 11, pp. 103, 2015

Wang, Zhang, Wang, Zhang, Mao, Zhuang, Tang, Luo, Zhou, Zhang: "Vascular endothelial growth factor stimulates endothelial differentiation from mesenchymal stem cells via Rho/myocardin-related transcription factor--a signaling pathway." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 7, pp. 1447-56, 2013

Images

Product Details anti-ROCK1 Antibody Target Details ROCK1 Application Details Handling References for anti-ROCK1 Antibody (ABIN707771) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-ROCK1 antibody (rho-Associated, Coiled-Coil Containing Protein Kinase 1) (pThr455) (ABIN707771) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-phospho-R...
Immunohistochemistry (IHC) image for anti-ROCK1 antibody (rho-Associated, Coiled-Coil Containing Protein Kinase 1) (pThr455) (ABIN707771) Formalin-fixed and paraffin embedded rat heart labeled with Anti-phospho-ROCK1(Thr455...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-ROCK1 antibody (rho-Associated, Coiled-Coil Containing Protein Kinase 1) (pThr455) (ABIN707771) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-phospho-R...