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Browse our anti-ATP2A2 (ATP2A2) Antibodies

Full name:
anti-ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 Antibodies (ATP2A2)
On www.antibodies-online.com are 57 ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) Antibodies from 13 different suppliers available. Additionally we are shipping ATP2A2 Kits (8) and ATP2A2 Proteins (8) and many more products for this protein. A total of 81 ATP2A2 products are currently listed.
Synonyms:
9530097L16Rik, ATP2, atp2a2, ATP2B, ca-p60a, D5Wsu150e, DAR, DD, mKIAA4195, Serca2, SERCA2A, SERCA2B, SercaII, zgc:55380
list all antibodies Gene Name GeneID UniProt
ATP2A2 488 P16615
ATP2A2 29693 P11507
ATP2A2 11938 O55143

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anti-Human ATP2A2 Antibodies:

anti-Rat (Rattus) ATP2A2 Antibodies:

anti-Mouse (Murine) ATP2A2 Antibodies:

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Top referenced anti-ATP2A2 Antibodies

  1. Amphibian Monoclonal ATP2A2 Primary Antibody for BP, ELISA - ABIN152688 : Sharp, McPherson, Dawson, Aoki, Campbell, Snyder: Differential immunohistochemical localization of inositol 1,4,5-trisphosphate- and ryanodine-sensitive Ca2+ release channels in rat brain. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1993 (PubMed)
    Show all 16 references for ABIN152688

  2. Human Polyclonal ATP2A2 Primary Antibody for ChIP, IP - ABIN151703 : Emter, McCune, Sparagna, Radin, Moore: Low-intensity exercise training delays onset of decompensated heart failure in spontaneously hypertensive heart failure rats. in American journal of physiology. Heart and circulatory physiology 2005 (PubMed)
    Show all 12 references for ABIN151703

  3. Amphibian Monoclonal ATP2A2 Primary Antibody for FACS, ICC - ABIN152736 : Asahi, Kurzydlowski, Tada, MacLennan: Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs). in The Journal of biological chemistry 2002 (PubMed)
    Show all 11 references for ABIN152736

  4. Cow (Bovine) Polyclonal ATP2A2 Primary Antibody for IHC, WB - ABIN2782136 : Korosec, Glavac, Volavsek, Ravnik-Glavac: Alterations in genes encoding sarcoplasmic-endoplasmic reticulum Ca(2+) pumps in association with head and neck squamous cell carcinoma. in Cancer genetics and cytogenetics 2008 (PubMed)

More Antibodies against ATP2A2 Interaction Partners

Xenopus laevis ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) interaction partners

  1. Atp2a2/serca2 is found in a larger subset of cells, but is not ubiquitous as reported in adults.

Horse (Equine) ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) interaction partners

  1. the genomic organization and the equine ATP2A2 coding sequence and an association analysis for chronic pastern dermatitis using a sample of South German draft horses

Human ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) interaction partners

  1. study identifies a novel splice acceptor site mutation in the ATP2A2 gene, in a family showing Darier disease

  2. Data suggest that mutations of the sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) gene may lead to the occurrence of Darier disease (DD) in both familial and sporadic cases with DD.

  3. Phospholamban (show PLN Antibodies) and sarcolipin (show SLN Antibodies) are membrane proteins that differentially regulate SERCA (show ATP2A3 Antibodies) function. (Review)

  4. CAPN3 (show CAPN3 Antibodies) deficiency leads to degradation of SERCA (show ATP2A3 Antibodies) proteins and Ca2 (show CA2 Antibodies)+ dysregulation in the skeletal muscle.

  5. High SERCA2 expression is associated with colorectal cancer.

  6. Quantification of SERCA2 mRNA or protein expression levels revealed no differences in airway smooth muscle cells obtained from subjects with asthma compared to non-asthmatic controls.

  7. Inhibition of SERCA2 activity by curcumin disrupts the Ca(2 (show CA2 Antibodies)+) homeostasis and thereby promotes apoptosis in ovarian cancer cells.

  8. The association between Darier disease and bipolar disorder is manifest also in the population, and data suggest that genetic variability within the ATP2A2 gene that causes Darier disease also confers susceptibility for bipolar disorder.

  9. ATP2A2 mutation was found in patients diagnosed with Darier disease.

  10. Two novel missense mutations, p.R603I and p.G749V, in the ATP2A2 gene in two families containing individuals diagnosed with Darier disease.

Pig (Porcine) ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) interaction partners

  1. Data suggest that the beneficial effects of SERCA2a gene transfer may involve the attenuation of ER stress-associated myocardial apoptosis.

  2. Oxidative/nitrosative stress associated with lung resection influences SERCA2a activity independent of any influence on protein expression or phospholamban (show PLN Antibodies) phosphorylation.

  3. overexpression of SERCA2a by in vivo rAAV1-mediated intracoronary gene transfer preserved systolic function, potentially prevented diastolic dysfunction, and improved ventricular remodeling.

Rabbit ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) interaction partners

  1. Data show that rabbit cold tolerance is probably related to increased muscle oxidative metabolism and heat production by SERCA1 (show ATP2A1 Antibodies) and that these changes are not completely dependent on normal thyroid function.

  2. These results indicate a mechanism relating SERCA1 (show ATP2A1 Antibodies) vicinal-cysteines oxidation to muscle fatigue.

Mouse (Murine) ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) interaction partners

  1. Nevertheless, the functional role of protein serotonylation in controlling SAN automaticity is largely unexplored. In this study, we screened the cardiomyocytes proteins and found that sarco(endo)plasmic reticulum Ca ATPase (show CA-P60A Antibodies) type 2a (SERCA2a) can be serotonylated. Simulation studies using mathematical SAN cell model showed that variation of Ca(2 (show CA2 Antibodies)+) affinity of SERCA2a pump cause either tachycardia or bradycardia.

  2. Muscle RANK deletion had no significant effects on the sham or denervated slow-twitch soleus muscles. These data identify a novel role for RANK as a key regulator of Ca(2 (show CA2 Antibodies)+)storage and SERCA (show ATP2A3 Antibodies) activity, ultimately affecting denervated skeletal muscle function.

  3. Generated were mice harboring N-ethyl-N-nitrosourea (ENU)-induced allelic mutations in Serca2: three missense mutations and one nonsense mutation. Mice harboring these Serca2 mutations developed tumors that were categorized as either early onset squamous cell tumors (SCT), with development similar to null-type knockout mice [2,4] (aggressive form; M682, M814), or late onset tumors (mild form; M1049, M1162).

  4. Identify Atrap (show AGTRAP Antibodies) as a novel regulatory protein (show TGFB1 Antibodies) of the cardiac Ca(2+)-ATPase SERCA2a (show CA-P60A Antibodies). Suggest that Atrap (show AGTRAP Antibodies) enhances the activity of SERCA2a and, consequently, facilitates ventricular relaxation.

  5. CAPN3 (show CAPN3 Antibodies) deficiency leads to degradation of SERCA (show ATP2A3 Antibodies) proteins and Ca2 (show CA2 Antibodies)+ dysregulation in the skeletal muscle.

  6. Sustained activation of Toll-like receptor 9 (show TLR9 Antibodies) causes cardiac and systemic inflammation, and deterioration of SERCA2a depletion-mediated diastolic heart failure.

  7. The LRP1 (show LRP1 Antibodies)/Pyk2 (show PTK2B Antibodies) axis represses SERCA2 mRNA expression via HIF-1a (show HIF1A Antibodies).

  8. This first-in-class small-molecule activator targeting SERCA2a SUMOylation may serve as a potential therapeutic strategy for treatment of heart failure

  9. privileged signal communication between the beta1-adrenergic receptor and SERCA2a impaired in cardiac hypertrophy

  10. These data reveal myofibrillar Ca(2 (show CA2 Antibodies)+)-sensitivity to be an important determinant of the cardiac effects of SERCA2 haploinsufficiency and raise the possibility that Darier disease patients are more susceptible to heart failure under certain conditions.

Guinea Pig ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) interaction partners

  1. SERCA2a gene transfer in the failing heart not only improves contractile function but also directly restores electric stability through amelioration of key arrhythmogenic substrate.

ATP2A2 Antigen Profile

Antigen Summary

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with ATP2A2

  • ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (atp2a2) antibody
  • ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (ATP2A2) antibody
  • ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (Atp2a2) antibody
  • ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a (atp2a2a) antibody
  • 9530097L16Rik antibody
  • ATP2 antibody
  • atp2a2 antibody
  • ATP2B antibody
  • ca-p60a antibody
  • D5Wsu150e antibody
  • DAR antibody
  • DD antibody
  • mKIAA4195 antibody
  • Serca2 antibody
  • SERCA2A antibody
  • SERCA2B antibody
  • SercaII antibody
  • zgc:55380 antibody

Protein level used designations for ATP2A2

Calcium ATPase at 60A , ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 , Atp2a2 , sarcoplasmic/endoplasmic reticulum calcium ATPase 2 , sarcoplasmic/endoplasmic reticulum calcium ATPase 2-like , ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2 , SR Ca(2+)-ATPase 2 , calcium pump 2 , calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform , cardiac Ca2+ ATPase , endoplasmic reticulum class 1/2 Ca(2+) ATPase , SERCA2 , calcium ATPase , sarcoplasmic reticulum Ca2+-transport ATPase isoform , Ca(2+)-transport ATPase class 3 , sarcoplasmic/endoplasmic-reticulum Ca(2+) pump gene 2 , ATPase, Ca++ transporting, slow twitch 2 , sarco(endo)plasmic reticulum Ca(2+)-dependent ATPase 2 , sarco/endoplasmic reticulum Ca2+-ATPase 2 , sarcoplasmic reticulum slow-twitch Ca2 ATPase , serca2

GENE ID SPECIES
380096 Xenopus laevis
452231 Pan troglodytes
540568 Bos taurus
791242 Equus caballus
100398261 Callithrix jacchus
100597073 Nomascus leucogenys
488 Homo sapiens
403878 Canis lupus familiaris
396875 Sus scrofa
100038308 Oryctolagus cuniculus
29693 Rattus norvegicus
11938 Mus musculus
100174978 Cavia porcellus
493691 Felis catus
396446 Gallus gallus
393940 Danio rerio
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