anti-Human IL1R2 antibody for Enzyme Immunoassay

Recommended IL1R2 Antibody (supplied by: Log in to see )

Antigen
Interleukin 1 Receptor, Type II (IL1R2) Antibodies
  • CD121b
  • CDw121b
  • IL-1R-2
  • IL-1RT-2
  • IL-1RT2
  • IL1R2c
  • IL1RB
  • Il1r-2
  • interleukin 1 receptor, type II
  • IL1R2
  • Il1r2
Epitope
AA 273-300, Middle Region
19
17
12
12
7
7
6
6
4
4
3
3
2
2
2
2
2
1
1
1
Reactivity
Human
130
28
25
1
Host
Rabbit
79
48
14
1
1
Clonality
Polyclonal
Conjugate
This IL1R2 antibody is un-conjugated
6
6
5
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
76
71
29
14
13
13
9
9
7
5
3
2
2
1
1
1
1
1
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Catalog No. ABIN951182
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN303103 EIA IF IHC (p) IP WB Rabbit Log in to see Polyclonal
1 ABIN1105824 EIA Rabbit IgG Log in to see Polyclonal 1
1 ABIN1105825 EIA WB FITC Mouse IgG1 Log in to see 08-05-14 3
1 ABIN1105822 EIA Mouse IgG2a Log in to see 6G5 1
1 ABIN1105823 EIA WB Mouse IgG1 Log in to see 08-05-14 1
1 ABIN112603 EIA WB Mouse IgG1 Log in to see 49-20
1 ABIN5556641 EIA IP WB Rabbit Log in to see Polyclonal

General

Antigen Interleukin 1 Receptor, Type II (IL1R2) Antibodies
Epitope AA 273-300, Middle Region
(19), (17), (12), (12), (7), (7), (6), (6), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1)
Reactivity Human
(130), (28), (25), (1)
Host Rabbit
(79), (48), (14), (1), (1)
Clonality
Polyclonal
Conjugate This IL1R2 antibody is un-conjugated
(6), (6), (5), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(76), (71), (29), (14), (13), (13), (9), (9), (7), (5), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-IL1R2 Antibody

Target Details IL1R2 Application Details Handling ProductDetails: References for anti-IL1R2 antibody (ABIN951182) Images
Specificity This antibody recognizes CD121b / IL1R2.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Purified through a Protein A column followed by peptide affinity purification
Immunogen Synthetic peptide - KLH conjugated - corresponding to the central region (between 273-300aa) of human CD121b / IL1R2.
Isotype Ig

Target Details IL1R2

Product Details anti-IL1R2 Antibody Application Details Handling ProductDetails: References for anti-IL1R2 antibody (ABIN951182) Images back to top
Antigen
Alternative Name CD121b / IL1R2 (IL1R2 Antibody Abstract)
Background The protein encoded by the IL1R2 gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.Synonyms: CD121 antigen-like family member B, CDw121b, IL-1R-2, IL-1R-beta, IL1RB, Interleukin-1 receptor type II
Gene ID 7850
NCBI Accession NP_004624
Research Area CD Antigens, Surface Receptors of Immune Cells, Cytokines, Immunology, Virology, Inflammation, Cancer, Receptors
Pathways NF-kappaB Signaling

Application Details

Product Details anti-IL1R2 Antibody Target Details IL1R2 Handling ProductDetails: References for anti-IL1R2 antibody (ABIN951182) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL1R2 Antibody Target Details IL1R2 Application Details ProductDetails: References for anti-IL1R2 antibody (ABIN951182) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

ProductDetails: References for anti-IL1R2 antibody (ABIN951182)

Product Details anti-IL1R2 Antibody Target Details IL1R2 Application Details Handling Images back to top
Background publications

Romero, Friel, Velez Edwards, Kusanovic, Hassan, Mazaki-Tovi, Vaisbuch, Kim, Erez, Chaiworapongsa, Pearce, Bartlett, Salisbury, Anant, Vovis, Lee, Gomez, Behnke, Oyarzun, Tromp, Williams, Menon: "A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM)." in: American journal of obstetrics and gynecology, Vol. 203, Issue 4, pp. 361.e1-361.e30, 2010

Giroux, Elfassihi, Clément, Bussières, Bureau, Cole, Rousseau: "High-density polymorphisms analysis of 23 candidate genes for association with bone mineral density." in: Bone, Vol. 47, Issue 5, pp. 975-81, 2010

Images

Product Details anti-IL1R2 Antibody Target Details IL1R2 Application Details Handling ProductDetails: References for anti-IL1R2 antibody (ABIN951182) back to top
Supplier Images
Western Blotting (WB) image for anti-Interleukin 1 Receptor, Type II (IL1R2) (AA 273-300), (Middle Region) antibody (ABIN951182) Western blot analysis in WiDr cell line lysates (35ug/lane) using CD121b / IL1R2  Ant...