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anti-Mouse (Murine) TNFRSF1A antibody for Immunoassay

Recommended TNFRSF1A Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
  • cd120a
  • CD120a
  • fpf
  • FPF
  • MS5
  • p55
  • p55-R
  • p55-r
  • p60
  • TBP1
  • tbp1
  • TNF-alphaR1
  • TNF-R
  • tnf-r
  • TNF-R-I
  • TNF-R1
  • TNF-R55
  • TNFalpha-R1
  • tnfar
  • TNFAR
  • Tnfr-2
  • tnfr1
  • Tnfr1
  • TNFR1
  • TNFR1-d2
  • tnfr55
  • TNFR55
  • TNFR60
  • tnfr60
  • TNFR I
  • TNFRI
  • TNFRp55
  • TNFRSF1A
  • wu:fj65b10
  • xtnfr1
  • zgc:85914
Reactivity
Mouse (Murine)
325
162
82
39
34
32
28
15
10
9
9
8
7
4
4
2
2
1
1
Host
Armenian Hamster
258
110
17
17
16
14
1
Clonality
Monoclonal
Conjugate
This TNFRSF1A antibody is conjugated to FITC
32
30
28
13
10
9
5
5
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Immunoassay (IA), Flow Cytometry (FACS), Immunoprecipitation (IP)
261
166
150
113
102
68
53
34
31
23
21
12
11
10
6
2
2
2
2
2
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN2191848
$ 474.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008696448 ABIN2192161 Func IA FACS IP WB Rabbit IgG Log in to see Polyclonal 3
0.0008696448 ABIN2192210 Func IA FACS IP Armenian Hamster Log in to see 55R-170 2

Top referenced anti-TNFRSF1A antibody for Immunoassay

Similar anti-TNFRSF1A Antibodies

Application / Reactivity Mouse (Murine)
Blocking Reagent (BR) 1 Antibodies
ELISA 33 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 49 Antibodies
Functional Studies (Func) 8 Antibodies
Immunoassay (IA) 3 Antibodies
Immunocytochemistry (ICC) 21 Antibodies
Immunofluorescence (IF) 21 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 48 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 7 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 22 Antibodies
Immunoprecipitation (IP) 77 Antibodies
Intracellular Flow Cytometry (ICFC) 1 Antibodies
Mass Cytometry (CyTOF) 2 Antibodies
Neutralization (Neut) 4 Antibodies

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
Reactivity Mouse (Murine)
(325), (162), (82), (39), (34), (32), (28), (15), (10), (9), (9), (8), (7), (4), (4), (2), (2), (1), (1)
Host Armenian Hamster
(258), (110), (17), (17), (16), (14), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF1A antibody is conjugated to FITC
(32), (30), (28), (13), (10), (9), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Immunoassay (IA), Flow Cytometry (FACS), Immunoprecipitation (IP)
(261), (166), (150), (113), (102), (68), (53), (34), (31), (23), (21), (12), (11), (10), (6), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-TNFRSF1A Antibody

Target Details TNFRSF1A Application Details Handling References for anti-TNFRSF1A Antibody (ABIN2191848) Images
Sterility 0.2 μm filtered
Clone 55R-170

Target Details TNFRSF1A

Product Details anti-TNFRSF1A Antibody Application Details Handling References for anti-TNFRSF1A Antibody (ABIN2191848) Images back to top
Antigen
Alternative Name Tnf-Ri (TNFRSF1A Antibody Abstract)
Background The monoclonal antibody 55R-170 recognizes the extracellular part of mouse Tumor Necrosis Factor Receptor superfamily member 1A (TNF-RI), also known as CD120a or p55. TNF-RI belongs to the large TNF receptor family, among which TNF-RII (TNF-R p75-80), lymphotoxin-beta receptor (LTbetaR) and the Herpes virus entry mediator (HVEM). Ligands for these receptors belong to the Tumor Necrosis Factor (TNF) superfamily of cytokines, which activate signaling pathways for cell survival, death, and differentiation that orchestrate the development, organization and homeostasis of lymphoid, mammary, neuronal and ectodermal tissues. TNF-RI contains a characteristic structural cassette termed death domain in its sequence that is conserved within a distinct subset of other TNF-R family members, such as CD95, DR3, DR4, and DR5. This death domain, was characterized as being essential for induction of apoptosis in vitro and has been structurally conserved within these TNF-R superfamily members. Deletion of the death domain of the TNF-RI results in a non-functional receptor, indicating that the death domain is required for the signal transduction of the physiological functions of TNF-RI in vivo. TNF-RI is a 55 kD type I transmembrane protein and is expressed on a variety of cell types at low levels. It is considered to play a prominent role in cell stimulation by TNF-alpha. Induction of cytotoxicity and other functions are mediated largely via TNF-RI. TNF-RI is present as soluble form in body fluids (for instance plasma and CSF). This extracellular TNF-RI is generated by two mechanisms, namely proteolytic cleavage of TNF-RI ectodomains and release of full-length TNF-RI in the membranes of exosome-like vesicles. TNF-RI and TNF-RII both interact with the homomeric forms of LTbeta or TNF. However, TNF-RI functions as the high affinity receptor for soluble TNF (sTNF). TNF-RI has been shown to be involved in a wide variety of inflammatory diseases, among which neurodegenerative diseases (Parkinson's and Alzheimer's disease), multiple sclerosis, asthma, atherosclerosis, rheumatology. The monoclonal antibody 55R-170 also recognizes the soluble receptor. Aliases TNFR type I, CD120a, TNF-RI, TNF-R55, TNFRp55, p55-R, TNF receptor alpha chain Immunogen Purified soluble extracellular domain of mouse TNF-RI
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Handling References for anti-TNFRSF1A Antibody (ABIN2191848) Images back to top
Application Notes For flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details References for anti-TNFRSF1A Antibody (ABIN2191848) Images back to top
Buffer PBS, containing 1 % bovine serum albumin.
Storage 4 °C
Storage Comment Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
Expiry Date 12 months

References for anti-TNFRSF1A Antibody (ABIN2191848)

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details Handling Images back to top
Background publications

Pinckard, Sheehan, Schreiber: "Ligand-induced formation of p55 and p75 tumor necrosis factor receptor heterocomplexes on intact cells." in: The Journal of biological chemistry, Vol. 272, Issue 16, pp. 10784-9, 1997

Sheehan, Pinckard, Arthur, Dehner, Goeddel, Schreiber: "Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75." in: The Journal of experimental medicine, Vol. 181, Issue 2, pp. 607-17, 1995