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|Antigen||Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) Antibodies|
|Epitope||AA 63-244 Alternatives|
|Conjugate||This TNFSF11 antibody is un-conjugated Alternatives|
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Product Details anti-TNFSF11 AntibodyTarget Details TNFSF11 Application Details Handling Images
Human RANKL / OPGL / TNFSF11 / CD254
Has cross-reactivity with Cynomolgus TNFSF11 (Catalog # 90301-C01H) in ELISA assay
No cross-reactivity with Mouse TNFSF11 (Catalog # 50343-M01H) in ELISA assay
|No Cross-Reactivity||Mouse (Murine)|
|Characteristics||This antibody was obtained from a rabbit immunized with purified, recombinant Human RANKL / OPGL / TNFSF11 / CD254 (rh RANKL / OPGL / TNFSF11 / CD254, ABIN2004531 O14788-2, Gly63-Asp244, and was produced using recombinant antibody technology.|
|Endotoxin Level||< 3 EU/mg|
|Immunogen||Recombinant Human RANKL / OPGL / TNFSF11 / CD254 Protein (ABIN2004531)|
Target Details TNFSF11Product Details anti-TNFSF11 Antibody Application Details Handling Images back to top
|Alternative Name||TNFSF11 (TNFSF11 Antibody Abstract)|
Application DetailsProduct Details anti-TNFSF11 Antibody Target Details TNFSF11 Handling Images back to top
In a functional ELISA which immobilized recombinant Human TNFRSF11A (Catalog # 16078-H08H) at 2 μg/mL (100 μL/well) in the plate, the Rabbit anti-Human TNFSF11 Monoclonal Antibody (Catalog # 11682-R001) can block the binding of 0.2 μg/mL of recombinant Human TNFSF11 (Catalog # 11682-HNCH) to human TNFRSF11A,the EC50 is 0.48 μg/mL, Immobilized recombinant Human recombinant Human TNFRSF11B (Catalog # 10271-H08H) at 2 μg/mL in the plate, the Antibody can block the binding of 0.2 μg/mL of recombinant Human TNFSF11 (Catalog # 11682-HNCH) to human TNFRSF11B ,the EC50 is 1.02 μg/mL.
The neutralization activity of TNFSF11 Neutralizing Antibody is Measured by its ability to neutralize TNFSF11 induced osteoclast-like cell formation in RAW 264.7 mouse macrophages. The Neutralization titer (IC50) is typically 4-16 ng/mL in the presence of 30 ng/mL Recombinant Human RANKL/OPGL/TNFSF11/CD254.
|Restrictions||For Research Use only|
HandlingProduct Details anti-TNFSF11 Antibody Target Details TNFSF11 Application Details Images back to top
|Buffer||0.2 μm filtered solution in Histidine and Arginine buffer containing 120 mM NaCl, 0.02 % Tween 80, pH 6.0|
|Storage||4 °C,-20 °C,-80 °C|
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
|Expiry Date||12 months|
ImagesProduct Details anti-TNFSF11 Antibody Target Details TNFSF11 Application Details Handling back to top