|Antigen||Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) Antibodies|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This TNFSF11 antibody is un-conjugated Alternatives|
Blocking Antibody (Inhibition), ELISA, Western Blotting (WB)
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Product Details anti-TNFSF11 AntibodyTarget Details TNFSF11 Application Details Handling Images
|Immunogen||RANKL antibody was raised in rabbit using highly pure recombinant murine sRANKL as the immunogen.|
Target Details TNFSF11Product Details anti-TNFSF11 Antibody Application Details Handling Images back to top
|Alternative Name||RANKL (TNFSF11 Antibody Abstract)|
|Background||RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic-cell-membrane protein, which by interacting with RANKL augments the ability of dendritic cells to stimulate naïve T-cell proliferation in a mixed lymphocyte reaction, to promote the survival of RANK + T cells, and to regulate T-cell-dependent immune response. RANKL, which is expressed in a variety of cells including osteoblasts, fibroblasts, activated T-cells and bone marrow stromal cells, is also capable of interacting with a decoy receptor called OPG.|
|Molecular Weight||19.4 kDa (predicted detection band MW)|
|Research Area||Immunology, Adaptive Immunity, Atherosclerosis, Innate Immunity, Cytokines, Extracellular Matrix, Growth Factors|
Application DetailsProduct Details anti-TNFSF11 Antibody Target Details TNFSF11 Handling Images back to top
ELISA: 0.5-2 µg/mL, Inhibition: 0.05 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.
|Restrictions||For Research Use only|
HandlingProduct Details anti-TNFSF11 Antibody Target Details TNFSF11 Application Details Images back to top
|Buffer||Lyophilized from PBS, pH 7.2.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.|