anti-Human Tumor Necrosis Factor antibody for Functional Studies

Recommended Tumor Necrosis Factor Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor (TNF) Antibodies
  • TNF
  • tnf
  • dif
  • tnfa
  • xtnf
  • TNF-a
  • tnfsf2
  • tnf-alpha
  • TNF-alpha
  • DIF
  • TNFA
  • TNFSF2
  • TNFalpha
  • Tnfa
  • Tnfsf1a
  • RATTNF
  • TNFa
  • cTNF
  • TNF-ALPHA
  • Cachectin
  • Tnf-alpha
  • tnfa-like
  • tumor necrosis factor (TNF superfamily, member 2)
  • tumor necrosis factor
  • tumour necrosis factor alpha-like
  • tumor necrosis factor alpha
  • lipopolysaccharide-induced TNF factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • TNF
  • tnf
  • tnf-alpha
  • LITAF
  • Tnf
  • tnfb
Reactivity
Human
1250
461
359
145
136
119
119
63
55
41
29
18
14
12
9
7
6
4
4
4
4
2
1
1
1
1
Host
Mouse
934
519
184
48
10
9
7
6
4
3
2
Clonality
Monoclonal
Conjugate
This Tumor Necrosis Factor antibody is un-conjugated
169
100
74
50
32
30
28
27
26
25
25
25
25
25
24
24
24
23
13
9
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Functional Studies (Func)
887
858
622
321
287
230
219
190
138
118
96
69
29
29
26
22
20
18
14
9
7
7
6
6
6
5
5
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Catalog No. ABIN1109382
$ 533.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN115771 EIA Func IHC (p) WB Mouse IgG1 Log in to see 2
1 ABIN610451 Func FACS IHC WB FITC Mouse IgG1 Log in to see J1D9 2
1 ABIN610452 Func FACS IHC WB PE Mouse IgG1 Log in to see J1D9 2
1 ABIN781720 ELISA (Capture) Func EIA Mouse IgG1 Log in to see 2C8 4
1 ABIN614424 Func EIA WB Mouse IgG1 Log in to see MAb1
1 ABIN1109383 Func EIA IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see 52B83 4
1 ABIN1109384 Func EIA IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see 4H31 1
1 ABIN1109402 Func IP WB Biotin Mouse IgG1 Log in to see T1 1
1 ABIN1109386 Func IP WB Mouse IgG1 Log in to see T1 1
1 ABIN126018 EIA Func FACS IHC (fro) Rat IgG1 Log in to see MP9-20A4 2
1 ABIN5556640 EIA Func IHC (fro) IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN5556639 EIA Func IHC (fro) IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN1981885 Func IHC (f) ICC FACS ELISA FITC Mouse IgG1 Log in to see MAb11 5
1 ABIN1109388 Func EIA IHC (fro) IP WB Mouse IgG1 Log in to see 4H31 2
1 ABIN191333 ELISA (Capture) Func IHC ELISA Mouse IgG1 Log in to see 2C8
1 ABIN114560 EIA Func IHC (p) Mouse IgG1 Log in to see CH8820
1 ABIN191332 Func IHC ELISA Mouse IgG1 Log in to see 1D9
1 ABIN2749009 Func ELISA WB Mouse IgG1 Log in to see MAb1 4
1 ABIN1690734 Func ELISA WB Mouse IgG1 Log in to see MAb1 6
1 ABIN1690740 ELISA FACS Func ICC IHC (f) PE Mouse IgG1 Log in to see MAb11 5

General

Antigen Tumor Necrosis Factor (TNF) Antibodies
Reactivity Human
(1250), (461), (359), (145), (136), (119), (119), (63), (55), (41), (29), (18), (14), (12), (9), (7), (6), (4), (4), (4), (4), (2), (1), (1), (1), (1)
Host Mouse
(934), (519), (184), (48), (10), (9), (7), (6), (4), (3), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Tumor Necrosis Factor antibody is un-conjugated
(169), (100), (74), (50), (32), (30), (28), (27), (26), (25), (25), (25), (25), (25), (24), (24), (24), (23), (13), (9), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Functional Studies (Func)
(887), (858), (622), (321), (287), (230), (219), (190), (138), (118), (96), (69), (29), (29), (26), (22), (20), (18), (14), (9), (7), (7), (6), (6), (6), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 5 references available
Supplier Log in to see

Product Details anti-Tumor Necrosis Factor Antibody

Target Details Tumor Necrosis Factor Application Details Handling ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN1109382) Images
Specificity Recognises both natural and recombinant Human TNF-alpha It recognises TNF-alpha bound on its receptor.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ion Exchange Chromatography
Sterility 0.22 μm filtered
Immunogen Recombinant Human TNF-alpha
Clone B-C7
Isotype IgG1

Target Details Tumor Necrosis Factor

Product Details anti-Tumor Necrosis Factor Antibody Application Details Handling ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN1109382) Images back to top
Antigen
Alternative Name Tumor Necrosis Factor (TNF-Alpha) (TNF Antibody Abstract)
Background Synonyms: Cachectin, TNF, TNF-a, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2
Gene ID 7124
NCBI Accession NP_000585
UniProt P01375
Research Area Cytokines, Growth Factors, Receptors, Immunology, Inflammation, Cancer, Virology
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus

Application Details

Product Details anti-Tumor Necrosis Factor Antibody Target Details Tumor Necrosis Factor Handling ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN1109382) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Tumor Necrosis Factor Antibody Target Details Tumor Necrosis Factor Application Details ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN1109382) Images back to top
Concentration 1.0 mg/mL
Buffer PBS, Sterile-filtered through 0.22 μm and treated to remove endotoxins. Carrier and preservative free
Preservative Without preservative
Handling Advice DO NOT FREEZE!
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN1109382)

Product Details anti-Tumor Necrosis Factor Antibody Target Details Tumor Necrosis Factor Application Details Handling Images back to top
Background publications

Arduise, Abache, Li, Billard, Chabanon, Ludwig, Mauduit, Boucheix, Rubinstein, Le Naour: "Tetraspanins regulate ADAM10-mediated cleavage of TNF-alpha and epidermal growth factor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 10, pp. 7002-13, 2008

Dyugovskaya, Lavie, Lavie: "Phenotypic and functional characterization of blood gammadelta T cells in sleep apnea." in: American journal of respiratory and critical care medicine, Vol. 168, Issue 2, pp. 242-9, 2003

Hamacher, Lucas, Lijnen, Buschke, Dunant, Wendel, Grau, Suter, Ricou: "Tumor necrosis factor-alpha and angiostatin are mediators of endothelial cytotoxicity in bronchoalveolar lavages of patients with acute respiratory distress syndrome." in: American journal of respiratory and critical care medicine, Vol. 166, Issue 5, pp. 651-6, 2002

Boillot, Capellier, Racadot, Wijdenes, Herve, Barale: "Pilot clinical trial of an anti-TNF alpha monoclonal antibody for the treatment of septic shock." in: Clinical intensive care : international journal of critical & coronary care medicine, Vol. 6, Issue 2, pp. 52-6, 1995

Hervé, Flesch, Tiberghien, Wijdenes, Racadot, Bordigoni, Plouvier, Stephan, Bourdeau, Holler: "Phase I-II trial of a monoclonal anti-tumor necrosis factor alpha antibody for the treatment of refractory severe acute graft-versus-host disease." in: Blood, Vol. 79, Issue 12, pp. 3362-8, 1992