Browse our anti-POFUT1 (POFUT1) Antibodies

On www.antibodies-online.com are 65 Protein O-Fucosyltransferase 1 (POFUT1) Antibodies from 23 different suppliers available. Additionally we are shipping POFUT1 Proteins (11) and POFUT1 Kits (6) and many more products for this protein. A total of 90 POFUT1 products are currently listed.
Synonyms:
DDD2, Fut12, mKIAA0180, O-Fuc-T, O-FucT-1, O-FUT, OFUCT1, pofut1, zgc:110472
list all antibodies Gene Name GeneID UniProt
POFUT1 23509 Q9H488
POFUT1 140484 Q91ZW2
POFUT1 311551 Q6EV70

Most Popular Reactivities for anti-POFUT1 (POFUT1) Antibodies

anti-Human POFUT1 Antibodies:

anti-Mouse (Murine) POFUT1 Antibodies:

anti-Rat (Rattus) POFUT1 Antibodies:

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More Antibodies against POFUT1 Interaction Partners

Human Protein O-Fucosyltransferase 1 (POFUT1) interaction partners

  1. Our findings suggested that overexpression of Pofut1 and activated Notch1 (show NOTCH1 Antibodies) signaling may be associated with a poor prognosis in breast cancer.

  2. POFUT1 gene expression in gastric cancer

  3. POFUT1, POGLUT1 (show POGLUT1 Antibodies) and ADAM10 (show ADAM10 Antibodies) are processing enzymes that are involved in different steps of Notch (show NOTCH1 Antibodies) receptor activation in the epidermis[10]; the roles of these unique enzymes in a single pathway may explain both the overlapping and distinct clinical features of DDD (show KRT5 Antibodies) and RAK (show FRK Antibodies) patients

  4. High expression of POFUT1 correlates with aggressive clinicopathological characteristics and poor prognosis of hepatocellular carcinoma patients.

  5. The upregulation of poFUT1 by LIF (show LIF Antibodies) facilitated trophoblast cell migration and invasion through activating the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling pathway.

  6. Silencing of Pofut1 expression exerted antiproliferative and antiadhesive effects on hepatocytes.

  7. Only a novel 1-bp deletion (c.246+5delG) in POFUT1 was found in a Chinese family with Dowling-Degos disease (DDD (show KRT5 Antibodies)). No other novel mutation or this deletion was detected in POFUT1 in a second DDD (show KRT5 Antibodies) family and a sporadic DDD (show KRT5 Antibodies) case by Sanger Sequencing.

  8. Identification of six pathogenic POFUT1 mutations in Dowling-Degos disease patients of different ethnic origin.

  9. POFUT1 expression can contribute to cancer progression and that POFUT1 may serve as a diagnostic marker and a therapeutic target for OSCCs.

  10. The protein product of POFUT1 plays a significant and conserved role in melanin synthesis and transport.

Mouse (Murine) Protein O-Fucosyltransferase 1 (POFUT1) interaction partners

  1. The POFUT1 binds EGF (show EGF Antibodies)-like domains of the hEGF type and that the highly correlated presence of POFUT1 and fucosylatable hEGFs has accompanied animal evolution.

  2. Loss of Pofut1 expression is associated with Muscle Aging-Related Phenotypes.

  3. results demonstrated that POFUT1-mediated O-fucosylation of NOTCH (show NOTCH1 Antibodies) receptors regulates myogenic cell differentiation and affects postnatal muscle growth in mice

  4. results establish the critical role of Pofut1 on Notch (show NOTCH1 Antibodies) pathway activation during myogenic differentiation

  5. mDLL1 O-fucosylation by POFUT1 is dispensable for ligand function

  6. Loss of Pofut1 is associated with myeloid hyperplasia and impaired lymphopoiesis.

  7. Pofut1 and O-fucose have roles in mammalian Notch (show NOTCH1 Antibodies) signaling

  8. Pofut1 is required for Notch (show NOTCH1 Antibodies) signaling upstream of NICD1.

  9. These data are consistent with a role for Pofut1 in AChR aggregation during synaptogenesis via the regulation of the synaptogenic activity of muscle agrin (show AGRN Antibodies).

  10. Reduced POFUT1 levels might affect Notch (show NOTCH1 Antibodies) trafficking or overall O-fucosylation.

POFUT1 Antigen Profile

Antigen Summary

This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Alternative names and synonyms associated with POFUT1

  • protein O-fucosyltransferase 1 (POFUT1) antibody
  • protein O-fucosyltransferase 1 (pofut1) antibody
  • protein O-fucosyltransferase 1 (Pofut1) antibody
  • DDD2 antibody
  • Fut12 antibody
  • mKIAA0180 antibody
  • O-Fuc-T antibody
  • O-FucT-1 antibody
  • O-FUT antibody
  • OFUCT1 antibody
  • pofut1 antibody
  • zgc:110472 antibody

Protein level used designations for POFUT1

GDP-fucose protein O-fucosyltransferase 1 , putative protein-O-fucosyltransferase , O-FucT-1 , peptide-O-fucosyltransferase 1 , protein-O-fucosyltransferase 1 , protein-O-fucosyltransferase , protein O-fucosyltransferase 1 , o-fucosyltransferase protein

GENE ID SPECIES
395070 Gallus gallus
397627 Sus scrofa
403029 Danio rerio
449504 Pan troglodytes
496411 Xenopus (Silurana) tropicalis
589493 Strongylocentrotus purpuratus
609881 Canis lupus familiaris
100125467 Oryzias latipes
100294553 Pongo abelii
23509 Homo sapiens
140484 Mus musculus
311551 Rattus norvegicus
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