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Browse our anti-High Mobility Group AT-Hook 1 (HMGA1) Antibodies

Full name:
anti-High Mobility Group AT-Hook 1 Antibodies (HMGA1)
On www.antibodies-online.com are 131 High Mobility Group AT-Hook 1 (HMGA1) Antibodies from 22 different suppliers available. Additionally we are shipping High Mobility Group AT-Hook 1 Proteins (20) and High Mobility Group AT-Hook 1 Kits (14) and many more products for this protein. A total of 177 High Mobility Group AT-Hook 1 products are currently listed.
Synonyms:
AL023995, ENSMUSG00000041059, HMG-I(Y), HMG-R, HMG-Y, HMGA1, Hmga1a, Hmga1b, Hmgi, Hmgi-rs1, Hmgiy, Hmgy, wu:fb12b06, wu:fb18f11, wu:fc19f01, wu:fi38b05, zgc:85677
list all antibodies Gene Name GeneID UniProt
HMGA1 111241 P17095
HMGA1 3159 P17096
HMGA1 117062 Q8K585

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Most Popular Reactivities for anti-High Mobility Group AT-Hook 1 (HMGA1) Antibodies

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All available anti-High Mobility Group AT-Hook 1 Antibodies

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Top referenced anti-High Mobility Group AT-Hook 1 Antibodies

  1. Human Polyclonal HMGA1 Primary Antibody for IHC, ELISA - ABIN185443 : Chiappetta, Botti, Monaco, Pasquinelli, Pentimalli, Di Bonito, DAiuto, Fedele, Iuliano, Palmieri, Pierantoni, Giancotti, Fusco: HMGA1 protein overexpression in human breast carcinomas: correlation with ErbB2 expression. in Clinical cancer research : an official journal of the American Association for Cancer Research 2004 (PubMed)
    Show all 2 references for ABIN185443

  2. Human Polyclonal HMGA1 Primary Antibody for FACS, IF - ABIN653050 : Mu, Liu, Zhou, Xu, Jiang, Wang, Qu: Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation, invasion, and proliferation associated with let-7 down-regulation in retinoblastomas. in Human pathology 2010 (PubMed)
    Show all 2 references for ABIN653050

  3. Human Polyclonal HMGA1 Primary Antibody for EIA, FACS - ABIN952761 : Kim, Lee, Park, Kim, Lee, Cho, Shin, Cho, Lee, Han, Yoo, Lee: Identification of 15 loci influencing height in a Korean population. in Journal of human genetics 2010 (PubMed)
    Show all 2 references for ABIN952761

  4. Human Polyclonal HMGA1 Primary Antibody for ELISA, WB - ABIN451785 : Liau, Rocha, Matros, Redston, Whang: High mobility group AT-hook 1 (HMGA1) is an independent prognostic factor and novel therapeutic target in pancreatic adenocarcinoma. in Cancer 2008 (PubMed)

More Antibodies against High Mobility Group AT-Hook 1 Interaction Partners

Mouse (Murine) High Mobility Group AT-Hook 1 (HMGA1) interaction partners

  1. Studies define a novel HMGA1-MMP-2 (show MMP2 Antibodies) pathway involved in a subset of human carcinosarcomas and tumor progression in murine models.

  2. Mouse embryonic fibroblasts null for the Hmga1 gene show downregulation of Bub1 (show BUB1 Antibodies), Bub1b (show BUB1B Antibodies), Mad2l1 (show MAD2L1 Antibodies) and Ttk SAC (show ADCY10 Antibodies) genes, and present several features of chromosomal instability, such as nuclear abnormalities, binucleation, micronuclei and karyotypic alterations.

  3. Taken together, our data demonstrate that miR (show MLXIP Antibodies)-625 suppresses cell proliferation and migration by targeting HMGA1 and suggest miR (show MLXIP Antibodies)-625 as a promising prognostic biomarker and a potential therapeutic target for breast cancer.

  4. Inactivation of the Cdkn2a (show CDKN2A Antibodies) locus cooperates with HMGA1 to drive T-cell leukemogenesis.

  5. Increased HMGA1 expression is associated with pituitary and thyroid tumors.

  6. activated HMGA1 regulates cell proliferation through the Notch1 (show NOTCH1 Antibodies) signaling pathway, which represents an important molecular pathway leading to leukemogenesis.

  7. Data propose that, by affecting the expression of both IGFBP protein species, HMGA1 can serve as a modulator of IGF-I (show IGF1 Antibodies) activity, thus representing an important novel mediator of glucose disposal.

  8. HMGA1 contributes to the neurogenic potential of neural precursor cells in the early stages of neocortical development.

  9. Elevated expression of HMGA1 is associated with the transition of prostate cancer (PCa (show ENPP1 Antibodies)) cells from androgen-sensitive to androgen-independent growth and plays a role in the cell growth of androgen-independent PCa (show ENPP1 Antibodies) cells.

  10. The data in the present study reveal a role of Hmga1 in transcriptional silencing in T cell lineages and leukemic cells.

Human High Mobility Group AT-Hook 1 (HMGA1) interaction partners

  1. The results reported here indicate a critical role of HMGA1 in the development of glioblastoma multiforme; its suppression impairs proliferation and self-renewal of brain tumor stem cells

  2. miR (show MLXIP Antibodies)-214 expression was poor while that of HMGA1 was high in cervical and colorectal cancer tissues. miR (show MLXIP Antibodies)-214-re-expression or HMGA1 downregulation inhibited proliferation, migration and invasion of cancer cells while miR (show MLXIP Antibodies)-214 inhibition had opposite effects. miR (show MLXIP Antibodies)-214 was demonstrated to bind to the wild-type 3' untranslated region of HMGA1 but not with its mutant.

  3. HMGA1 is frequently expressed in cirrhotic tissues and HCCs (show HCCS Antibodies) and its expression is associated with high Edmondson grade and worse prognosis in HCC (show FAM126A Antibodies).

  4. Studies define a novel HMGA1-MMP-2 (show MMP2 Antibodies) pathway involved in a subset of human carcinosarcomas and tumor progression in murine models.

  5. HMGA1 may function as an oncogene (show RAB1A Antibodies) and modulate endometrial cancer cell migration and invasion by activating Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway.

  6. Increased HMGA1 in pulmonary arterial endothelial cells resulting from dysfunctional BMPr2 (show BMPR2 Antibodies) signaling can transition endothelium to smooth muscle-like cells associated with pulmonary arterial hypertension.

  7. in splenic hemangioma with t(3;6)(q26;p21 (show CDKN1A Antibodies)), the entire coding region of HMGA1 comes under the control of the TBL1XR1 (show TBL1XR1 Antibodies) promoter, bringing about dysregulation of HMGA1

  8. This is the first report for the association between HMGA1 and S100A13 (show S100A13 Antibodies) expression in the modulation of thyroid cancer growth and invasion.

  9. Data indicate that the high mobility group (show SSRP1 Antibodies) A1 (HMGA1) proteomic signature has prognostic value in breast cancer.

  10. In breast cancer patients, high levels of HMGA1 and CCNE2 (show CCNE2 Antibodies) expression are associated with the YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) signature.

Pig (Porcine) High Mobility Group AT-Hook 1 (HMGA1) interaction partners

  1. distinct loci exist for growth and fatness in the two populations and identified HMGA1 and PLAG1 (show PLAG1 Antibodies) as strong candidate genes on SSC7 and SSC4, respectively.

  2. Characterization of polymorphisms in the HMGA1 gene in relation to growth and fat deposition.

Cow (Bovine) High Mobility Group AT-Hook 1 (HMGA1) interaction partners

  1. HMGA1 likely regulates certain aspects of the BoHV-1 latency-reactivation cycle.

High Mobility Group AT-Hook 1 (HMGA1) Antigen Profile

Antigen Summary

This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with High Mobility Group AT-Hook 1 (HMGA1)

  • high mobility group AT-hook I, related sequence 1 (Hmga1-rs1) antibody
  • high mobility group protein HMG-I/HMG-Y (TSC_c24220) antibody
  • high mobility group AT-hook 1a (hmga1a) antibody
  • high mobility group AT-hook 1 (HMGA1) antibody
  • high mobility group AT-hook 1 (Hmga1) antibody
  • high mobility group AT-hook 1 (Hmg-i) antibody
  • AL023995 antibody
  • ENSMUSG00000041059 antibody
  • HMG-I(Y) antibody
  • HMG-R antibody
  • HMG-Y antibody
  • HMGA1 antibody
  • Hmga1a antibody
  • Hmga1b antibody
  • Hmgi antibody
  • Hmgi-rs1 antibody
  • Hmgiy antibody
  • Hmgy antibody
  • wu:fb12b06 antibody
  • wu:fb18f11 antibody
  • wu:fc19f01 antibody
  • wu:fi38b05 antibody
  • zgc:85677 antibody

Protein level used designations for HMGA1

high mobility group protein HMG-I/HMG-Y , HMG-I(Y) , high mobility group protein A1 , high mobility group AT-hook protein 1 , high mobility group AT-hook 1 , high-mobility group (nonhistone chromosomal) protein isoforms I and Y , high mobility group protein R , nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y , high mobility group HMGA1A , high mobility group HMGA1B , non-histone protein , high-mobility group AT-hook 1 , high mobility group protein I , High mobility group AT-hook protein 1 , High mobility group protein A1 , high mobility group-I protein

GENE ID SPECIES
111241 Mus musculus
10178543 Thermus scotoductus SA-01
406447 Danio rerio
705105 Macaca mulatta
746594 Pan troglodytes
3159 Homo sapiens
442946 Canis lupus familiaris
100157848 Sus scrofa
618849 Bos taurus
15361 Mus musculus
117062 Rattus norvegicus
378795 Gallus gallus
100689040 Cricetulus griseus
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