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anti-Human ATM antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended ATM Antibody (supplied by: Log in to see )

Antigen
Ataxia Telangiectasia Mutated (ATM) Antibodies
  • ATM
  • Atm
  • CG6535
  • Dmel\\CG6535
  • Tefu
  • atm
  • atm/tefu
  • dATM
  • tef
  • Xatm
  • at1
  • atdc
  • tel1
  • telo1
  • AT1
  • ATA
  • ATC
  • ATD
  • ATDC
  • ATE
  • TEL1
  • TELO1
  • AI256621
  • C030026E19Rik
  • telomere fusion
  • ataxia telangiectasia mutated
  • ataxia telangiectasia mutated (atm)
  • ataxia telangiectasia mutated homolog (human)
  • tefu
  • atm
  • ATM
  • EDI_100660
  • CpipJ_CPIJ001772
  • BDBG_08252
  • PAAG_02532
  • MCYG_05088
  • VDBG_06833
  • ACLA_015700
  • AaeL_AAEL014900
  • MGYG_07634
  • PGTG_14279
  • Atm
  • LOC100349299
Epitope
full length
84
41
17
16
15
15
13
8
8
7
7
6
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Monkey, Mouse (Murine), Rat (Rattus)
348
130
67
19
4
1
1
Host
Mouse
229
93
17
8
3
Clonality
Monoclonal
Conjugate
This ATM antibody is un-conjugated
12
11
10
9
6
6
5
5
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Chromatin Immunoprecipitation (ChIP), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
207
123
105
85
77
67
60
43
27
22
13
4
4
2
2
1
1
1
1
Supplier
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Catalog No. ABIN151775
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.0823965 ABIN152102 ICC IF IHC (p) IP IHC PLA WB Rabbit AA 2550-2600 Log in to see Polyclonal 2
12.0823965 ABIN499359 EIA IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 1
12.0823965 ABIN498773 IHC (p) Rabbit pSer1981 Log in to see Polyclonal
12.0823965 ABIN498863 IHC (p) Rabbit Log in to see Polyclonal
12.0823965 ABIN213900 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN151772 ICC IF IHC (p) IP IHC WB Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12 15
1 ABIN151030 ICC FACS IF IHC (p) IP IHC ELISA WB Rabbit C-Term Log in to see Polyclonal 74
1 ABIN196822 IHC (p) Rabbit pSer1981 Log in to see Polyclonal 4
1 ABIN1689293 IHC (p) Rabbit IgG Log in to see SP224
1 ABIN302280 IHC (p) IP WB Mouse IgG1 AA 980-1512 Log in to see 3-00E-008
1 ABIN1689292 FACS IHC (p) Rabbit IgG Log in to see SP224
1 ABIN2888954 IHC (p) ELISA Rabbit IgG AA 1950-1999 Log in to see Polyclonal
1 ABIN222001 IHC (p) WB Rabbit IgG AA 1980-2338 Log in to see Polyclonal
1 ABIN302783 IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN679103 IF (p) IHC (p) Rabbit IgG pSer1981 Log in to see Polyclonal 1
1 ABIN214233 IHC (p) IP WB Mouse IgG1 AA 980-1512 Log in to see 3E8
1 ABIN685582 FACS IF (cc) IF (p) IHC (p) Rabbit IgG AA 2700-2750 Log in to see Polyclonal
1 ABIN1822141 IHC (p) Rabbit IgG pSer1981 Log in to see Polyclonal
1 ABIN4282171 ICC IF IHC IHC (p) WB DyLight 488 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282178 ICC IF IHC IHC (p) WB DyLight 405 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12

Top referenced anti-ATM antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-ATM Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Chromatin Immunoprecipitation (ChIP) 2 Antibodies 2 Antibodies
ELISA 14 Antibodies 33 Antibodies
Flow Cytometry (FACS) 27 Antibodies 42 Antibodies
Immunocytochemistry (ICC) 33 Antibodies 54 Antibodies
Immunofluorescence (IF) 33 Antibodies 61 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 13 Antibodies 13 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 14 Antibodies 14 Antibodies
Immunohistochemistry (IHC) 36 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 34 Antibodies
Immunoprecipitation (IP) 11 Antibodies
Western Blotting (WB) 40 Antibodies
Biochemical Assay (BCA) 2 Antibodies
BioImaging (BI) 1 Antibodies

General

Antigen Ataxia Telangiectasia Mutated (ATM) Antibodies
Epitope full length
(84), (41), (17), (16), (15), (15), (13), (8), (8), (7), (7), (6), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Monkey, Mouse (Murine), Rat (Rattus)
(348), (130), (67), (19), (4), (1), (1)
Host Mouse
(229), (93), (17), (8), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This ATM antibody is un-conjugated
(12), (11), (10), (9), (6), (6), (5), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Chromatin Immunoprecipitation (ChIP), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(207), (123), (105), (85), (77), (67), (60), (43), (27), (22), (13), (4), (4), (2), (2), (1), (1), (1), (1)
Pubmed 20 references available
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Product Details anti-ATM Antibody

Target Details ATM Application Details Handling References for anti-ATM Antibody (ABIN151775) Images
Specificity This antibody recognizes full-length ATM, a 350- kDa nuclear phosphoprotein.
Purification Immunogen affinity purified
Immunogen Recombinant protein expressed in E. coli corresponding to amino acids 2577-3056.
Clone 2C1
Isotype IgG1

Target Details ATM

Product Details anti-ATM Antibody Application Details Handling References for anti-ATM Antibody (ABIN151775) Images back to top
Antigen
Alternative Name ATM (ATM Antibody Abstract)
Background Gene Symbol: ATM
Molecular Weight Theoretical MW: 370 kDa
Gene ID 472
UniProt Q13315
Research Area Cancer, DNA/RNA
Pathways p53 Signaling, Apoptosis, DNA Damage Repair

Application Details

Product Details anti-ATM Antibody Target Details ATM Handling References for anti-ATM Antibody (ABIN151775) Images back to top
Application Notes Western Blot 1:500-1:3000, Chromatin Immunoprecipitation 1:10 - 1:500, Flow Cytometry, ELISA 1:100 - 1:2000, Immunohistochemistry 10 - 1:500, Immunocytochemistry/Immunofluorescence, Immunoprecipitation 1-10 μg/mL, Immunohistochemistry-Paraffin 5 μg/mLIHC-R. ICC/IF usage reported in scientifc literature (Harry Scherthan, et.al., 2000 and Yiyoung Liu, et.al., 2006). ELISA usage reported in scientific literature. WB: Predicted molecular weight: 350 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Handling

Product Details anti-ATM Antibody Target Details ATM Application Details References for anti-ATM Antibody (ABIN151775) Images back to top
Format Liquid
Concentration 1.85 mg/mL
Buffer PBS ( pH 7.4)
Buffer contains: No Preservative
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage -80 °C,-20 °C
Storage Comment Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

References for anti-ATM Antibody (ABIN151775)

Product Details anti-ATM Antibody Target Details ATM Application Details Handling Images back to top
Product cited in:

Simões, Martins, Ferreira: "Early intranuclear replication of African swine fever virus genome modifies the landscape of the host cell nucleus." in: Virus research, Vol. 210, pp. 1-7, 2015

Park, Kong, Kim, Lee, Park: "Inhibition of S-adenosylhomocysteine hydrolase decreases cell mobility and cell proliferation through cell cycle arrest." in: American journal of cancer research, Vol. 5, Issue 7, pp. 2127-38, 2015 Further details: Western Blotting

Batenburg, Thompson, Hendrickson, Zhu: "Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation." in: The EMBO journal, Vol. 34, Issue 10, pp. 1399-416, 2015 (Sample species: Mouse (Murine)). Further details: Western Blotting

Vermezovic, Adamowicz, Santarpia, Rustighi, Forcato, Lucano, Massimiliano, Costanzo, Bicciato, Del Sal, dAdda di Fagagna: "Notch is a direct negative regulator of the DNA-damage response." in: Nature structural & molecular biology, Vol. 22, Issue 5, pp. 417-24, 2015 (Sample species: Human). Further details: Western Blotting,Immunohistochemistry (Paraffin-embedded Sections)

Muraki, Han, Miller, Murnane: "Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks." in: Nucleic acids research, Vol. 43, Issue 16, pp. 7911-30, 2015 (Sample species: Human). Further details: Western Blotting

Gutiérrez-González, Belda-Iniesta, Bargiela-Iparraguirre, Dominguez, García Alfonso, Perona, Sanchez-Perez: "Targeting Chk2 improves gastric cancer chemotherapy by impairing DNA damage repair." in: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 3, pp. 347-60, 2013 (Sample species: Human). Further details: Western Blotting

Min, Bruhn, Grigaravicius, Zhou, Li, Krüger, Siddeek, Greulich, Popp, Meisezahl, Calkhoven, Bürkle, Xu, Wang: "Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation." in: Nature communications, Vol. 4, pp. 2993, 2013 (Sample species: Mouse (Murine)). Further details: Western Blotting

Murad, Cullen, McKenzie, Ryan, Thorburn, Gueven, Kobayashi, Birrell, Yang, Dörk, Becherel, Grattan-Smith, Lavin: "Mitochondrial dysfunction in a novel form of autosomal recessive ataxia." in: Mitochondrion, Vol. 13, Issue 3, pp. 235-45, 2013 (Sample species: Human). Further details: Western Blotting

Simões, Martins, Ferreira: "Host DNA damage response facilitates African swine fever virus infection." in: Veterinary microbiology, Vol. 165, Issue 1-2, pp. 140-7, 2013

Hao, Duncan, Su, Li, Silvester, Hong, You, Brenner, Gorrini, Haight, Wakeham, You-Ten, McCracken, Elia, Li, Detmar, Jurisicova, Hobeika, Reth, Sheng, Lang, Ohashi, Zhong, Wang, Mak: "The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis." in: The Journal of experimental medicine, Vol. 209, Issue 1, pp. 173-86, 2012

Kang, So, Ouchi: "Deregulation of DNA damage response pathway by intercellular contact." in: The Journal of biological chemistry, Vol. 287, Issue 20, pp. 16246-55, 2012 Further details: Western Blotting

Zhang, de Toledo, Pandey, Guo, Pain, Li, Azzam: "Role of the translationally controlled tumor protein in DNA damage sensing and repair." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 16, pp. E926-33, 2012

Ai, Skehan, Saydi, Lin, Brown: "Ataxia-Telangiectasia, Mutated (ATM)/Nuclear Factor κ light chain enhancer of activated B cells (NFκB) signaling controls basal and DNA damage-induced transglutaminase 2 expression." in: The Journal of biological chemistry, Vol. 287, Issue 22, pp. 18330-41, 2012 (Sample species: Human). Further details: ELISA

Yan, Greer, Cao, Kolb, Cowan: "RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activation." in: Breast cancer research : BCR, Vol. 14, Issue 2, pp. R60, 2012 (Sample species: Human). Further details: Western Blotting

Hsu, Lee, Yeh, Chen, Wu, Wang, Chen, Hung, Liu, Chen, Hsiao, Wang, Tsou, Tsou, Wu, Chang, Lin: "58-kDa microspherule protein (MSP58) is novel Brahma-related gene 1 (BRG1)-associated protein that modulates p53/p21 senescence pathway." in: The Journal of biological chemistry, Vol. 287, Issue 27, pp. 22533-48, 2012 (Sample species: Human). Further details: Western Blotting

Mahajan, Coppola, Rawal, Chen, Lawrence, Engelman, Lawrence, Mahajan: "Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer." in: The Journal of biological chemistry, Vol. 287, Issue 26, pp. 22112-22, 2012 (Sample species: Human). Further details: Western Blotting

Hardee, Marciscano, Medina-Ramirez, Zagzag, Narayana, Lonning, Barcellos-Hoff: "Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β." in: Cancer research, Vol. 72, Issue 16, pp. 4119-29, 2012 (Sample species: Human). Further details: Western Blotting

Baritaud, Cabon, Delavallée, Galán-Malo, Gilles, Brunelle-Navas, Susin: "AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation." in: Cell death & disease, Vol. 3, pp. e390, 2012 Further details: Western Blotting

Shi, Felley-Bosco, Marti, Stahel: "Differential effects of lovastatin on cisplatin responses in normal human mesothelial cells versus cancer cells: implication for therapy." in: PLoS ONE, Vol. 7, Issue 9, pp. e45354, 2012 (Sample species: Human). Further details: Western Blotting

Sakasai, Sakai, Iimori, Kiyonari, Matsuoka, Kakeji, Kitao, Maehara: "CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 17, Issue 12, pp. 962-70, 2012 (Sample species: Human). Further details: Western Blotting

Images

Product Details anti-ATM Antibody Target Details ATM Application Details Handling References for anti-ATM Antibody (ABIN151775) back to top
Supplier Images
Western Blotting (WB) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (full length) (ABIN151775) anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody
Western Blotting (WB) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (full length) (ABIN151775) Detection of ATM (Anti-ATM 2C1, ABIN151775) or ATR by western blot in human Raji whol...
Western Blotting (WB) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (full length) (ABIN151775) Western Blot: ATM Antibody (2C1) [ABIN151775] - A. 30 ug U87-MG whole cell lysate/ext...
Western Blotting (WB) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (full length) (ABIN151775) Western Blot: ATM Antibody (2C1) [ABIN151775] - A. 30 ug NT2D1 whole cell lysate/extr...
Western Blotting (WB) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (full length) (ABIN151775) Western Blot: ATM Antibody (2C1) [ABIN151775] - analysis of ATM in U2OS sarcoma cells...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (full length) (ABIN151775) Immunohistochemistry-Paraffin: ATM Antibody (2C1) [ABIN151775] - Human Testis (formal...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (full length) (ABIN151775) Immunohistochemistry-Paraffin: ATM Antibody (2C1) [ABIN151775] - Human Kidney (formal...