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anti-Human ATM antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended ATM Antibody (supplied by: Log in to see )

Antigen
Ataxia Telangiectasia Mutated (ATM) Antibodies
  • AI256621
  • at1
  • AT1
  • ATA
  • ATC
  • ATD
  • ATDC
  • atdc
  • ATE
  • Atm
  • ATM
  • atm
  • atm/tefu
  • C030026E19Rik
  • CG6535
  • dATM
  • Dmel\\CG6535
  • tef
  • Tefu
  • tel1
  • TEL1
  • TELO1
  • telo1
  • Xatm
Epitope
C-Term
86
36
17
14
13
13
13
7
7
7
5
5
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
320
114
59
14
6
4
1
Host
Rabbit
213
84
14
8
3
Clonality
Polyclonal
Conjugate
This ATM antibody is un-conjugated
11
10
8
8
6
6
5
5
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
196
111
99
89
77
73
53
23
22
14
11
4
3
2
2
1
1
1
1
Supplier
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Catalog No. ABIN499359
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.34236017 ABIN498773 IHC (p) Rabbit pSer1981 Log in to see Polyclonal
0.34236017 ABIN498863 IHC (p) Rabbit Log in to see Polyclonal
0.34236017 ABIN213900 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.0008985354 ABIN251422 ICC IF IHC (p) IP IHC WB Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12 3
0.0008985354 ABIN196822 IHC (p) Rabbit pSer1981 Log in to see Polyclonal 4
0.0008985354 ABIN1689293 IHC (p) Rabbit IgG Log in to see SP224
0.0008985354 ABIN189039 ICC IF IHC (p) IP IHC WB Rabbit IgG Ser1981 Log in to see Y170
0.0008985354 ABIN302280 IHC (p) IP WB Mouse IgG1 AA 980-1512 Log in to see 3-00E-008
0.0008985354 ABIN1689292 FACS IHC (p) Rabbit IgG Log in to see SP224
0.0008985354 ABIN2888954 IHC (p) ELISA Rabbit IgG AA 1950-1999 Log in to see Polyclonal
0.0008985354 ABIN302783 IHC (p) WB Rabbit Log in to see Polyclonal
0.0008985354 ABIN685582 IF (cc) IF (p) IHC (p) Rabbit IgG AA 2700-2750 Log in to see Polyclonal
0.0008985354 ABIN222001 IHC (p) WB Rabbit IgG AA 1980-2338 Log in to see Polyclonal
0.0008985354 ABIN258963 ICC IF IHC (p) IP IHC WB Rabbit IgG Ser1981 Log in to see EP1890Y
0.0008985354 ABIN214233 IHC (p) IP WB Mouse IgG1 AA 980-1512 Log in to see 3E8
0.0008985354 ABIN152102 ICC IF IHC (p) IP IHC PLA WB Rabbit AA 2550-2600 Log in to see Polyclonal
0.0008985354 ABIN151775 ICC IF IHC (p) IP IHC ELISA WB Mouse IgG1 AA 2577-3056 Log in to see 2C1
0.0008985354 ABIN1822141 IHC (p) Rabbit IgG pSer1981 Log in to see Polyclonal
0.0008985354 ABIN685584 IHC (p) Biotin Rabbit IgG AA 2700-2750 Log in to see Polyclonal
0.0008985354 ABIN685591 IHC (p) HRP Rabbit IgG AA 2700-2750 Log in to see Polyclonal

Top referenced anti-ATM antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-ATM Antibodies

Application / Reactivity Human
Biochemical Assay (BCA) 2 Antibodies
BioImaging (BI) 1 Antibodies
Chromatin Immunoprecipitation (ChIP) 1 Antibodies
Dot Blot (DB) 22 Antibodies
ELISA 99 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 14 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 62 Antibodies
Immunofluorescence (IF) 87 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies
Immunohistochemistry (IHC) 120 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 78 Antibodies
Immunoprecipitation (IP) 101 Antibodies
Proximity Ligation Assay (PLA) 4 Antibodies
Western Blotting (WB) 209 Antibodies

General

Antigen Ataxia Telangiectasia Mutated (ATM) Antibodies
Epitope C-Term
(86), (36), (17), (14), (13), (13), (13), (7), (7), (7), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(320), (114), (59), (14), (6), (4), (1)
Host Rabbit
(213), (84), (14), (8), (3)
Clonality
Polyclonal
Conjugate This ATM antibody is un-conjugated
(11), (10), (8), (8), (6), (6), (5), (5), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(196), (111), (99), (89), (77), (73), (53), (23), (22), (14), (11), (4), (3), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-ATM Antibody

Target Details ATM Application Details Handling References for anti-ATM Antibody (ABIN499359) Images
Specificity This antibody reacts to ATM.
Purification Affinity chromatography purified via peptide column
Immunogen ATM antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human ATM.
Isotype IgG

Target Details ATM

Product Details anti-ATM Antibody Application Details Handling References for anti-ATM Antibody (ABIN499359) Images back to top
Antigen
Alternative Name ATM (ATM Antibody Abstract)
Background DNA double strand breaks represent a major threat to an organism's genome. Eukaryotic cells have developed mechanisms that sense the presence this damage and initiate suitable responses that can include DNA repair, cell cycle delay, and programmed cell death. The ATM (mutated in Ataxia-Telangiectasia) protein kinase is activated following the formation of DNA double strand breaks, phosphorylating p53 and another kinase CHK2. This initiates a signaling cascade leading to the phosphorylation and inhibition of Cdc25, ultimately preventing cell cycle progression. In some cell types, such as the hemapoietic system, this leads to apoptosis instead of cell cycle arrest. Multiple isoforms of ATM are known to exist.Synonyms: A-T mutated, ATDC, Ataxia telangiectasia mutated, Serine-protein kinase ATM, TEL1, TELO1
Gene ID 472
UniProt Q13315
Research Area Cancer, DNA/RNA
Pathways p53 Signaling, Apoptosis, DNA Damage Repair

Application Details

Product Details anti-ATM Antibody Target Details ATM Handling References for anti-ATM Antibody (ABIN499359) Images back to top
Application Notes ELISA. Western Blot: ATM antibody can be used for detection of ATM at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-ATM Antibody Target Details ATM Application Details References for anti-ATM Antibody (ABIN499359) Images back to top
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

References for anti-ATM Antibody (ABIN499359)

Product Details anti-ATM Antibody Target Details ATM Application Details Handling Images back to top
Background publications

Cahill, Connor, Carney: "Mechanisms of eukaryotic DNA double strand break repair." in: Frontiers in bioscience : a journal and virtual library, Vol. 11, pp. 1958-76, 2005

Images

Product Details anti-ATM Antibody Target Details ATM Application Details Handling References for anti-ATM Antibody (ABIN499359) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (C-Term) (ABIN499359) Immunohistochemistry of ATM in human lymph node tissue with this product atM antibody...
Western Blotting (WB) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (C-Term) (ABIN499359) Western blot analysis of ATM in Daudi whole cell lysate with this product atM antibod...