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anti-Monkey ATM antibody for Immunohistochemistry

Recommended ATM Antibody (supplied by: Log in to see )

Antigen
Ataxia Telangiectasia Mutated (ATM) Antibodies
  • AI256621
  • at1
  • AT1
  • ATA
  • ATC
  • ATD
  • ATDC
  • atdc
  • ATE
  • Atm
  • ATM
  • atm
  • atm/tefu
  • C030026E19Rik
  • CG6535
  • dATM
  • Dmel\\CG6535
  • tef
  • Tefu
  • tel1
  • TEL1
  • TELO1
  • telo1
  • Xatm
Epitope
AA 2577-3056
86
37
17
14
13
13
13
7
7
7
5
5
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Monkey, Mouse (Murine), Rat (Rattus)
321
114
59
14
6
4
1
Host
Mouse
214
84
14
8
3
Clonality
Monoclonal
Conjugate
This ATM antibody is un-conjugated
11
10
8
8
6
6
5
5
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
197
111
99
89
77
74
53
23
22
14
11
4
4
2
2
1
1
1
1
Supplier
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Catalog No. ABIN151775
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0011326484 ABIN1721458 ChIP ICC FACS IF IP IHC ELISA WB Mouse IgG1 kappa Log in to see 2C1

Similar anti-ATM Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Chromatin Immunoprecipitation (ChIP) 1 Antibodies 1 Antibodies
ELISA 15 Antibodies 29 Antibodies
Flow Cytometry (FACS) 1 Antibodies 12 Antibodies
Immunocytochemistry (ICC) 34 Antibodies 50 Antibodies
Immunofluorescence (IF) 34 Antibodies 57 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 12 Antibodies 12 Antibodies
Immunohistochemistry (IHC) 34 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 38 Antibodies
Immunoprecipitation (IP) 35 Antibodies
Western Blotting (WB) 42 Antibodies
Biochemical Assay (BCA) 2 Antibodies
BioImaging (BI) 1 Antibodies

General

Antigen Ataxia Telangiectasia Mutated (ATM) Antibodies
Epitope AA 2577-3056
(86), (37), (17), (14), (13), (13), (13), (7), (7), (7), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Monkey, Mouse (Murine), Rat (Rattus)
(321), (114), (59), (14), (6), (4), (1)
Host Mouse
(214), (84), (14), (8), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This ATM antibody is un-conjugated
(11), (10), (8), (8), (6), (6), (5), (5), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(197), (111), (99), (89), (77), (74), (53), (23), (22), (14), (11), (4), (4), (2), (2), (1), (1), (1), (1)
Pubmed 20 references available
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Product Details anti-ATM Antibody

Target Details ATM Application Details Handling References for anti-ATM Antibody (ABIN151775) Images
Specificity NB100-309 recognizes full-length ATM, a 350-kDa nuclear phosphoprotein.
Purification Protein G purified
Immunogen Recombinant protein expressed in E. coli corresponding to amino acids 2577-3056.
Clone 2C1
Isotype IgG1

Target Details ATM

Product Details anti-ATM Antibody Application Details Handling References for anti-ATM Antibody (ABIN151775) Images back to top
Antigen
Alternative Name ATM (ATM Antibody Abstract)
Background Ataxia-telangiectasia (A-T) is a recessive childhood disease caused by mutations in theATM (AT-mutated) gene. Symptoms include neurological abnormalities that causeunsteady posture, dilated blood vessels, infertility, radiation sensitivity, immunedeficiencies and lymphoid malignancies. It appears that the diverse defects seen inATM null mammals are manifestations of disparate signal transduction defects. The ATM protein is related to a family of proteins through a c-terminalphoshatidylinositol 3-kinase (PI3-kinase) domain. Members of the PI3-kinase family ofproteins are involved in cell cycle control, DNA replication, recombination and repair.ATM also shares sequence homology with portions of the yeast RAD3 gene. The mainrole of ATM appears to be induction of a DNA-damage control pathway in response togenotoxic insults, such as ionizing radiation or anti-tumor medications and theprogrammed DNA breaks of meiosis. Alternate Names: anti-AT complementation group A antibody, anti-AT complementation group C antibody,anti-AT complementation group D antibody, anti-AT complementation group E antibody,anti-AT mutated protein antibody, anti-AT1 antibody, anti-ATA antibody, anti-Ataxiatelangiectasia gene mutated antibody.
Gene Symbol: ATM
Gene ID 472, 11920, 300711
Research Area Cancer, DNA/RNA
Pathways p53 Signaling, Apoptosis, DNA Damage Repair

Application Details

Product Details anti-ATM Antibody Target Details ATM Handling References for anti-ATM Antibody (ABIN151775) Images back to top
Application Notes For ICC/IF: Please refer to the publication by Harry Scherthan, et.al, 2000 and Yiyoung Liu, et.al, 2006. ELISA was reported in scientific literature.
Recommended dilutions: ELISA 1:100-1:2000, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 5 µg/mL, Immunoprecipitation 1-10 µg/mL, Western Blot 1:500-1:1000
Restrictions For Research Use only

Handling

Product Details anti-ATM Antibody Target Details ATM Application Details References for anti-ATM Antibody (ABIN151775) Images back to top
Buffer PBS [pH 7.4]
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Aliquot and store at -20 °C or -80 °C.

References for anti-ATM Antibody (ABIN151775)

Product Details anti-ATM Antibody Target Details ATM Application Details Handling Images back to top
Product cited in:

Gutiérrez-González, Belda-Iniesta, Bargiela-Iparraguirre, Dominguez, García Alfonso, Perona, Sanchez-Perez: "Targeting Chk2 improves gastric cancer chemotherapy by impairing DNA damage repair." in: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 3, pp. 347-60, 2013 (Sample species: Human). Further details: Western Blotting

Hao, Duncan, Su, Li, Silvester, Hong, You, Brenner, Gorrini, Haight, Wakeham, You-Ten, McCracken, Elia, Li, Detmar, Jurisicova, Hobeika, Reth, Sheng, Lang, Ohashi, Zhong, Wang, Mak: "The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis." in: The Journal of experimental medicine, Vol. 209, Issue 1, pp. 173-86, 2012

Kang, So, Ouchi: "Deregulation of DNA damage response pathway by intercellular contact." in: The Journal of biological chemistry, Vol. 287, Issue 20, pp. 16246-55, 2012 Further details: Western Blotting

Zhang, de Toledo, Pandey, Guo, Pain, Li, Azzam: "Role of the translationally controlled tumor protein in DNA damage sensing and repair." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 16, pp. E926-33, 2012

Ai, Skehan, Saydi, Lin, Brown: "Ataxia-Telangiectasia, Mutated (ATM)/Nuclear Factor κ light chain enhancer of activated B cells (NFκB) signaling controls basal and DNA damage-induced transglutaminase 2 expression." in: The Journal of biological chemistry, Vol. 287, Issue 22, pp. 18330-41, 2012 (Sample species: Human). Further details: ELISA

Yan, Greer, Cao, Kolb, Cowan: "RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activation." in: Breast cancer research : BCR, Vol. 14, Issue 2, pp. R60, 2012 (Sample species: Human). Further details: Western Blotting

Hsu, Lee, Yeh, Chen, Wu, Wang, Chen, Hung, Liu, Chen, Hsiao, Wang, Tsou, Tsou, Wu, Chang, Lin: "58-kDa microspherule protein (MSP58) is novel Brahma-related gene 1 (BRG1)-associated protein that modulates p53/p21 senescence pathway." in: The Journal of biological chemistry, Vol. 287, Issue 27, pp. 22533-48, 2012 (Sample species: Human). Further details: Western Blotting

Mahajan, Coppola, Rawal, Chen, Lawrence, Engelman, Lawrence, Mahajan: "Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer." in: The Journal of biological chemistry, Vol. 287, Issue 26, pp. 22112-22, 2012 (Sample species: Human). Further details: Western Blotting

Hardee, Marciscano, Medina-Ramirez, Zagzag, Narayana, Lonning, Barcellos-Hoff: "Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β." in: Cancer research, Vol. 72, Issue 16, pp. 4119-29, 2012 (Sample species: Human). Further details: Western Blotting

Baritaud, Cabon, Delavallée, Galán-Malo, Gilles, Brunelle-Navas, Susin: "AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation." in: Cell death & disease, Vol. 3, pp. e390, 2012 Further details: Western Blotting

Shi, Felley-Bosco, Marti, Stahel: "Differential effects of lovastatin on cisplatin responses in normal human mesothelial cells versus cancer cells: implication for therapy." in: PLoS ONE, Vol. 7, Issue 9, pp. e45354, 2012 (Sample species: Human). Further details: Western Blotting

Sakasai, Sakai, Iimori, Kiyonari, Matsuoka, Kakeji, Kitao, Maehara: "CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 17, Issue 12, pp. 962-70, 2012 (Sample species: Human). Further details: Western Blotting

Shi, Felley-Bosco, Marti, Orlowski, Pruschy, Stahel: "Starvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatin." in: BMC cancer, Vol. 12, pp. 571, 2012 (Sample species: Human). Further details: Western Blotting

Kozlov, Graham, Jakob, Tobias, Kijas, Tanuji, Chen, Robinson, Taucher-Scholz, Suzuki, So, Chen, Lavin: "Autophosphorylation and ATM activation: additional sites add to the complexity." in: The Journal of biological chemistry, Vol. 286, Issue 11, pp. 9107-19, 2011 (Sample species: Human). Further details: Western Blotting

Guo, Deshpande, Paull: "ATM activation in the presence of oxidative stress." in: Cell cycle (Georgetown, Tex.), Vol. 9, Issue 24, pp. 4805-11, 2011 Further details: Western Blotting

Ruiz, Mihaylov, Cotmore, Tattersall: "Recruitment of DNA replication and damage response proteins to viral replication centers during infection with NS2 mutants of Minute Virus of Mice (MVM)." in: Virology, Vol. 410, Issue 2, pp. 375-84, 2011

Urquhart, Gatei, Richard, Khanna: "ATM mediated phosphorylation of CHD4 contributes to genome maintenance." in: Genome integrity, Vol. 2, Issue 1, pp. 1, 2011 (Sample species: Human). Further details: Western Blotting

Cherubini, Naim, Caruso, Burla, Bogliolo, Cundari, Benihoud, Saggio, Rosselli: "The FANC pathway is activated by adenovirus infection and promotes viral replication-dependent recombination." in: Nucleic acids research, Vol. 39, Issue 13, pp. 5459-73, 2011 (Sample species: Human). Further details: Western Blotting

Shouse, Nobumori, Panowicz, Liu: "ATM-mediated phosphorylation activates the tumor-suppressive function of B56γ-PP2A." in: Oncogene, Vol. 30, Issue 35, pp. 3755-65, 2011 (Sample species: Human). Further details: Western Blotting

Bouquet, Ousset, Biard, Fallone, Dauvillier, Frit, Salles, Muller: "A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia." in: Journal of cell science, Vol. 124, Issue Pt 11, pp. 1943-51, 2011 (Sample species: Human). Further details: Western Blotting

Images

Product Details anti-ATM Antibody Target Details ATM Application Details Handling References for anti-ATM Antibody (ABIN151775) back to top
Supplier Images
Western Blotting (WB) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (AA 2577-3056) (ABIN151775) anti-Ataxia Telangiectasia Mutated (ATM) (AA 2577-3056) antibody
Western Blotting (WB) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (AA 2577-3056) (ABIN151775) Detection of ATM (Anti-ATM 2C1, ABIN151775) or ATR by western blot in human Raji whol...