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Browse our anti-NOXA (PMAIP1) Antibodies

Full name:
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 Antibodies (PMAIP1)
On www.antibodies-online.com are 135 Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) Antibodies from 18 different suppliers available. Additionally we are shipping NOXA Kits (6) and NOXA Proteins (6) and many more products for this protein. A total of 162 NOXA products are currently listed.
Synonyms:
APR, Noxa, PMAIP1, TN3, zgc:162379
list all antibodies Gene Name GeneID UniProt
PMAIP1 5366 Q13794
PMAIP1 58801 Q9JM54
PMAIP1 492821 Q5U777

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Most Popular Reactivities for anti-NOXA (PMAIP1) Antibodies

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anti-Human NOXA Antibodies:

anti-Mouse (Murine) NOXA Antibodies:

anti-Rat (Rattus) NOXA Antibodies:

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Top referenced anti-NOXA Antibodies

  1. Human Monoclonal NOXA Primary Antibody for ICC, IF - ABIN269360 : Deverman, Cook, Manson, Niederhoff, Langer, Rosová, Kulans, Fu, Weinberg, Heinecke, Roth, Weintraub: Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage. in Cell 2002 (PubMed)
    Show all 61 references for ABIN269360

  2. Human Polyclonal NOXA Primary Antibody for IHC (p), WB - ABIN4340476 : Eno, Zhao, Venkatanarayan, Wang, Flores, Li: Noxa couples lysosomal membrane permeabilization and apoptosis during oxidative stress. in Free radical biology & medicine 2013 (PubMed)
    Show all 5 references for ABIN4340476

  3. Human Polyclonal NOXA Primary Antibody for EIA, IHC (p) - ABIN500377 : Nakano, Vousden: PUMA, a novel proapoptotic gene, is induced by p53. in Molecular cell 2001 (PubMed)
    Show all 4 references for ABIN500377

  4. Human Polyclonal NOXA Primary Antibody for WB - ABIN223344 : Li, Chen, Clifton, Sullivan, Dalton, Gabrilovich, Nefedova: Combined inhibition of Notch signaling and Bcl-2/Bcl-xL results in synergistic antimyeloma effect. in Molecular cancer therapeutics 2010 (PubMed)
    Show all 3 references for ABIN223344

  5. Human Polyclonal NOXA Primary Antibody for ELISA, ICC - ABIN4340478 : Bai, Ahmad, Wang, Li, Choy, Kim, Kirkiles-Smith, Maher, Karras, Bennett, Bothwell, Pober, Tellides: Interferon-gamma induces X-linked inhibitor of apoptosis-associated factor-1 and Noxa expression and potentiates human vascular smooth muscle cell apoptosis by STAT3 activation. in The Journal of biological chemistry 2008 (PubMed)

  6. Human Polyclonal NOXA Primary Antibody for ICC, IF - ABIN4340477 : Kelly, Espitia, Mahalingam, Oyajobi, Coffey, Giles, Carew, Nawrocki: Reovirus therapy stimulates endoplasmic reticular stress, NOXA induction, and augments bortezomib-mediated apoptosis in multiple myeloma. in Oncogene 2012 (PubMed)

  7. Human Polyclonal NOXA Primary Antibody for IHC (p), WB - ABIN318708 : Oda, Ohki, Murasawa, Nemoto, Shibue, Yamashita, Tokino, Taniguchi, Tanaka: Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. in Science (New York, N.Y.) 2000 (PubMed)

More Antibodies against NOXA Interaction Partners

Zebrafish Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) interaction partners

  1. Therefore, the current findings indicate that Noxa is a novel regulator of early mitosis before 75% epiboly stage when it translates into a key mediator of apoptosis in subsequent embryogenesis.

Human Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) interaction partners

  1. high levels of miR21 expression may induce gastric cancer migration and invasion via the downregulation of Noxa expression

  2. Inhibition of SIRT1 (show SIRT1 Antibodies) could induce the Noxa expression in A549/DDP (show TIMM8A Antibodies) cells.

  3. Fluorizoline bind to prohibitin (show PHB Antibodies), inducing mitochondrial apoptotic pathway through NOXA and BIM (show BCL2L11 Antibodies) upregulation.

  4. Noxa demethylation has a role in Bortezomib resistance in mantle cell lymphoma

  5. SATB1 (show SATB1 Antibodies) as a Dual Regulator of Anti-Apoptotic BCL2 (show BCL2 Antibodies) and Pro-Apoptotic NOXA Genes

  6. ALK (show ALK Antibodies)-negative anaplastic large cell lymphoma is sensitive to bortezomib through Noxa upregulation and release of Bax (show BAX Antibodies) from Bcl-2 (show BCL2 Antibodies).

  7. BCL2 (show BCL2 Antibodies) and BCLX (show BCL2L1 Antibodies) phosphorylation represents a priming event in mitotic cell death that is triggered by NOXA-dependent MCL1 (show MCL1 Antibodies) degradation. The MCL1 (show MCL1 Antibodies) decay allows in turn BIM (show BCL2L11 Antibodies)-dependent cell death.

  8. Overexpression of nonphosphorylatable Noxa resulted in enhanced mitochondria-mediated apoptosis in the infected epithelium.

  9. Results reveal that oncogenic activation of MEK (show MAP2K1 Antibodies)/ERK (show EPHB2 Antibodies) drives Noxa expression to promote autophagy, and suggest that Noxa has an indirect anti-apoptosis role in melanoma cells under nutrient starvation conditions.

  10. Overall, these data reveal a Noxa-mediated signaling pathway that couples lysosomal membrane permeabilization with mitochondrial outer membrane permeabilization and ultimate apoptosis during oxidative stress.

Mouse (Murine) Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) interaction partners

  1. Fluorizoline bind to prohibitin (show PHB Antibodies), inducing mitochondrial apoptotic pathway through NOXA and BIM (show BCL2L11 Antibodies) upregulation.

  2. In addition, studies in leukemia Jurkat T cells support the existence of the Sall2 (show SALL2 Antibodies)/Noxa axis, and the significance of this axis on the apoptotic response to doxorubicin in cancer cells.

  3. Our data demonstrate that ES cells are uniquely sensitive to CDK1 (show CDK1 Antibodies) inhibition via a p53 (show TP53 Antibodies)/NOXA/MCL1 (show MCL1 Antibodies) pathway.

  4. Overall, these data reveal a Noxa-mediated signaling pathway that couples lysosomal membrane permeabilization with mitochondrial outer membrane permeabilization and ultimate apoptosis during oxidative stress.

  5. by preventing the consumption of IL-15 (show IL15 Antibodies), Bim (show BCL2L11 Antibodies) limits the role of Noxa and Puma (show BBC3 Antibodies) in causing the death of effector cells with less memory potential.

  6. Induction of noxa does not influence ischemic neuronal injury.

  7. the current findings indicate that Noxa is a novel regulator of early mitosis before 75% epiboly stage when it translates into a key mediator of apoptosis in subsequent embryogenesis.

  8. Noxa controls expansion of erythroid precursors and RBC (show CACNA1C Antibodies) production in vivo under conditions of induced anemia.

  9. Noxa is targeted to the mitochondrial membrane where it neutralises Mcl-1 (show MCL1 Antibodies) via its C-terminal BH3-domain.

  10. Induction of senescence was only impaired in cells from the p21 (show D4S234E Antibodies)-/- puma (show BBC3 Antibodies)-/- noxa-/- mice but abrogated in cells from the p53 (show TP53 Antibodies)-/- mice.

NOXA (PMAIP1) Antigen Profile

Antigen Summary

Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.

Alternative names and synonyms associated with NOXA (PMAIP1)

  • phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1) antibody
  • phorbol-12-myristate-13-acetate-induced protein 1 (pmaip1) antibody
  • phorbol-12-myristate-13-acetate-induced protein 1 (Pmaip1) antibody
  • APR antibody
  • Noxa antibody
  • PMAIP1 antibody
  • TN3 antibody
  • zgc:162379 antibody

Protein level used designations for PMAIP1

phorbol-12-myristate-13-acetate-induced protein 1 , Noxa , PMA-induced protein 1 , adult T cell leukemia-derived PMA-responsive , immediate-early-response protein APR , protein Noxa

GENE ID SPECIES
397278 Sus scrofa
737247 Pan troglodytes
751765 Danio rerio
5366 Homo sapiens
58801 Mus musculus
492821 Rattus norvegicus
100502558 Canis lupus familiaris
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