Browse our anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) Antibodies

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anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) Antibodies (HIF1A)
On www.antibodies-online.com are 662 Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) Antibodies from 37 different suppliers available. Additionally we are shipping Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) Kits (78) and Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) Proteins (50) and many more products for this protein. A total of 804 Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) products are currently listed.
Synonyms:
AA959795, bHLHe78, hif-1a, HIF-1alpha, HIF1, HIF1-alpha, hif1a, HIF1alpha, MOP1, PASD8
list all antibodies Gene Name GeneID UniProt
HIF1A 15251 Q61221
HIF1A 3091 Q16665
Anti-Rat HIF1A HIF1A 29560 O35800

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All available anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) Antibodies

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Top referenced anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) Antibodies

  1. Bird (Avian) Monoclonal HIF1A Primary Antibody for ChIP, GS - ABIN151053 : An, Maeng, Kang, Lee, Kim, Paik, Lee: Activation of Ras up-regulates pro-apoptotic BNIP3 in nitric oxide-induced cell death. in The Journal of biological chemistry 2006 (PubMed)
    Show all 128 references for 151053

  2. Cow (Bovine) Monoclonal HIF1A Primary Antibody for ICC, IF - ABIN151061 : Abbate, Santini, Biondi-Zoccai, Scarpa, Vasaturo, Liuzzo, Bussani, Silvestri, Baldi, Crea, Biasucci, Baldi: Cyclo-oxygenase-2 (COX-2) expression at the site of recent myocardial infarction: friend or foe? in Heart (British Cardiac Society) 2004 (PubMed)
    Show all 59 references for 151061

  3. Cow (Bovine) Monoclonal HIF1A Primary Antibody for ICC, IF - ABIN863097 : Surazynski, Miltyk, Prokop, Palka: The effect of estrogen on prolidase-dependent regulation of HIF-1α expression in breast cancer cells. in Molecular and cellular biochemistry 2013 (PubMed)
    Show all 9 references for 863097

  4. Human Monoclonal HIF1A Primary Antibody for IHC (p), IP - ABIN151762 : Gillespie, Whang, Ragel, Flynn, Kelly, Jensen: Silencing of hypoxia inducible factor-1alpha by RNA interference attenuates human glioma cell growth in vivo. in Clinical cancer research : an official journal of the American Association for Cancer Research 2007 (PubMed)
    Show all 6 references for 151762

  5. Human Polyclonal HIF1A Primary Antibody for IF, IHC (p) - ABIN392176 : Favaro, Nardo, Persano, Masiero, Moserle, Zamarchi, Rossi, Esposito, Plebani, Sattler, Mann, Mueller-Klieser, Ciminale, Amadori, Indraccolo: Hypoxia inducible factor-1alpha inactivation unveils a link between tumor cell metabolism and hypoxia-induced cell death. in The American journal of pathology 2008 (PubMed)
    Show all 3 references for 392176

  6. Human Polyclonal HIF1A Primary Antibody for FACS, IF - ABIN652389 : Lee, Lee, Kim, Kim, Jung, Seo, Park, Choi, Yim, Lee, Park, Yoo, Kim, Lee, Kim, Ryeom, Kim, Oh: Roles of arrest-defective protein 1(225) and hypoxia-inducible factor 1alpha in tumor growth and metastasis. in Journal of the National Cancer Institute 2010 (PubMed)
    Show all 2 references for 652389

  7. Human Monoclonal HIF1A Primary Antibody for EMSA, IF - ABIN114960 : Arany, Huang, Eckner, Bhattacharya, Jiang, Goldberg, Bunn, Livingston: An essential role for p300/CBP in the cellular response to hypoxia. in Proceedings of the National Academy of Sciences of the United States of America 1996 (PubMed)
    Show all 2 references for 114960

  8. Human Polyclonal HIF1A Primary Antibody for EIA, IHC (p) - ABIN360059 : Alexandru, Graumann, Smith, Kolawa, Fang, Deshaies: UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover. in Cell 2008 (PubMed)
    Show all 2 references for 360059

  9. Cow (Bovine) Polyclonal HIF1A Primary Antibody for WB - ABIN2780373 : Kitajima, Ide, Ohtsuka, Miyazaki: Induction of hepatocyte growth factor activator gene expression under hypoxia activates the hepatocyte growth factor/c-Met system via hypoxia inducible factor-1 in pancreatic cancer. in Cancer science 2008 (PubMed)

More Antibodies against Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) Interaction Partners

Mouse (Murine) Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) interaction partners

  1. HIF1alpha-dependent glycolytic activity is responsible for mTOR (show FRAP1 Antibodies)-deficient, increased myeloid-derived suppressive cell functional changes in IMH inflammation.

  2. Activation of HIF1A by prolonged in vivo hyperinsulinemia potentiates cancerous progression in estrogen receptor (show ESR1 Antibodies)-positive breast cancer cells.

  3. Endothelium-specific knockdown of HIF-1alpha impairs the ability of POMC (show POMC Antibodies) neurons to adapt to the changing metabolic environment in vivo, resulting in overeating after food deprivation in mice.

  4. In response to hypoxia, compared with rats, mice had higher minute ventilation, lower metabolic rate and higher expression of HIF-1alpha in the brainstem.

  5. in neurons HIF-1 and HIF-2 have redundant functions for cellular survival under ischemic conditions. By contrast, lack of anti-survival factors in Hif1a/Hif2a (show EPAS1 Antibodies)-deficient mice might protect from early acute neuronal cell death and neurological impairment, indicating a benefit of HIF-pathway inhibition in neurons in the very acute phase after ischemic stroke

  6. These results demonstrate that HIF-1alpha is critical for controlling the progression of infection with the fungal pathogen H. capsulatum by limiting IL-10 (show IL10 Antibodies).

  7. data illustrate that Hypoxia-inducible factor-1alpha (HIF-1alpha) is required for optimal innate leishmanicidal immune responses and, thereby, contributes to the cure of cutaneous leishmaniasis

  8. Hif1a expression is increased in myocardium/skeletal muscle of colonic adenocarcinoma-bearing mice.

  9. Despite the hypoxic nature of the bone marrow microenvironment, Hif-1alpha is dispensable for cell-autonomous Hematopoietic stem cell maintenance.

  10. we have identified HIF-1alpha as a novel regulator of IFN-gamma (show IFNG Antibodies)-dependent immunity that coordinates an immunometabolic program essential for control of M. tuberculosis infection in vitro and in vivo.

Human Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) interaction partners

  1. a down regulation of STEAP4 (show STEAP4 Antibodies) and up-regulation of HIF-1alpha are observed in morbidly obese patients

  2. HIF-1A overexpression is associated with pneumococcal infection.

  3. low temperature plasma treatment significantly induced the expression of HIF1alpha, an upstream regulator of angiogenesis.

  4. Results show that HIF1alpha expression was up-regulated in breast cancer cells under hypoxia induction.

  5. High expression of HIF1A is associated with inflammation in arsenite-induced liver carcinogenesis.

  6. gankyrin (show PSMD10 Antibodies) regulates HIF-1alpha protein stability and cyclin D1 (show CCND1 Antibodies) expression, ultimately mediating FSH (show BRD2 Antibodies)-driven ovarian cancer cell proliferation

  7. It was concluded that compromised pulmonary artery smooth muscle cells HIF-1alpha expression may contribute to the increased tone that characterizes pulmonary hypertension.

  8. this study therefore identifies NRF-1 (show NFE2L1 Antibodies) as a novel regulator of HIF-1a.

  9. Activation of HIF1A by prolonged in vivo hyperinsulinemia potentiates cancerous progression in estrogen receptor (show ESR1 Antibodies)-positive breast cancer cells.

  10. we established a new regulatory model of COL1A1 (show COL1A1 Antibodies) regulation by HIF-1, and bring out its relationship with Sp3 transcription factor (show SP3 Antibodies). In a fundamental level, these findings give insights in the mechanisms controlling COL1A1 (show COL1A1 Antibodies) gene expression.

Pig (Porcine) Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) interaction partners

  1. a high expression of hypoxia induced factor-1a (HIF-1a) and heat shock protein 70 (HSP70 (show HSP70 Antibodies)) was noted

  2. Induction of ischemic osteonecrosis results in IL-6 (show IL6 Antibodies) production in the articular cartilage through an HIF-1-dependent pathway.

  3. Upregulation of VEGF (show VEGFA Antibodies) during hypoxia in chondrocyte is mediated partially through HIF-1alpha.

  4. HIF-1alpha activates Sox9 (show SOX9 Antibodies) expression and enhances Sox9 (show SOX9 Antibodies)-mediated transcriptional activity.

  5. Intramyocardial delivery of mesenchymal stem cells seems to trigger the release of angiogenic HIF-1alpha more effectively than does intracoronary delivery.

  6. immunostaining for HIF-1alpha and HIF-2alpha (show EPAS1 Antibodies) was observed during endochondral ossification, whereas only HIF-2alpha (show EPAS1 Antibodies) was present at sites of intramembranous ossification

  7. Downregulation of miR (show MYLIP Antibodies)-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 (show SIRT1 Antibodies) and recapitulates hypoxia preconditioning in cardiac myocytes.

  8. Viable chondrocytes in the superficial layer of the epiphyseal cartilage showed HIF-1alpha activation and VEGF upregulation with subsequent revascularization occurring in the cartilage.

Cow (Bovine) Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) interaction partners

  1. inverse expression and localization pattern of HIF1A and vasohibins during different stages of ovarian function in cow

  2. Hypoxia increased the amounts of HIF1A protein, VEGF mRNA and VEGF protein in cultured bovine luteal cells.

  3. hypoxia-induced changes in vascular cell growth are altered by hyperglycemia via inhibition of HIF-1alpha expression and activity

  4. VEGF has an effect on the expression of its own transcription factor, HIF-1, and on VEGF itself

  5. Identify sphingosine-1-phosphate as a novel and potent nonhypoxic activator of HIF-1.

Rabbit Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) interaction partners

  1. Suggest supplemental oxygen inhibits HIF-1alpha/VEGF signaling to reduce smooth muscle proliferation in rabbit arteriovenous fistula model.

  2. HIF-1alpha-induced HSP70 (show HSP70 Antibodies) overexpression increased the expression levels of ECM (show MMRN1 Antibodies) genes and cell viability, and protected chondrocytes from apoptosis. HIF-1alpha may regulate anabolic effects of chondrocytes under hypoxic conditions by regulating HSP70 (show HSP70 Antibodies) expression

  3. Transcatheter arterial embolization of liver tumors increases the expression of HIF-1alpha at protein level in the residual viable tumor.

  4. Upregulation of HIF-1 protects cardiac myocyte function after ischemia/reperfusion by maintaining calcium release.

  5. HIF-1alpha expression in early atherosclerosis can promote the formation of neovascularization.

  6. Xells respond to hypoxia through a transcription factor, hypoxia-inducible factor 1

  7. Upregulation of HIF-1 could protect isolated cardiac myocytes against nitrate tolerance through a cyclic GMP protein kinase-independent mechanism and through a kinase-dependent mechanism in myocardial stunning.

  8. rhEPO can down-regulate HIF-1alpha expression in the retina of rabbits with acute high intraocular pressure.

  9. Increased HIF-1 alpha protects the functional effects of cyclic GMP thorough maintenance of cyclic GMP protein kinase activity after ischemic-reperfusion

Caenorhabditis elegans (C. elegans) Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) interaction partners

  1. blocking HIF-1 activity may promote survival in cells with compromised mitochondrial function.

  2. HIF-1-mediated activation of 5-HT (show DDC Antibodies) signalling promotes axon regeneration by activating both the RhoA (show RHOA Antibodies) and cAMP pathways.

  3. this study reports that neuronal stabilization of HIF-1 mediates these effects in Caenorhabditis elegans through a cell nonautonomous signal to the intestine, which results in activation of the xenobiotic detoxification enzyme flavin-containing monooxygenase-2 (FMO-2 (show FMO2 Antibodies)).

  4. AMPK (show PRKAA1 Antibodies) and HIF-1 may control immunity and longevity tightly by acting as feedback regulators of ROS (show ROS1 Antibodies)

  5. Growth in hypoxia increases longevity in wild-type worms but not in animals lacking HIF-1 or DAF-16. Conversely, hypoxia shortens life span in combination with overexpression of the antioxidant stress response protein SKN-1.

  6. Increased levels of hydrogen peroxide induce a HIF-1-dependent modification of lipid metabolism in AMPK (show PRKAA1 Antibodies) compromised C. elegans dauer larvae.

  7. These data show that HIF-1 regulates intestinal iron homeostasis during iron deficiency by activating and inhibiting genes involved in iron uptake and storage.

  8. Data indicate that genes sqrd-1, ethe-1 (show ETHE1 Antibodies), cysl-1, cysl-2 and HIF-1 are involved in survival to hydrogen sulfide (show SQRDL Antibodies) and hydrogen cyanide.

  9. Data show that stabilization of HIF-1 increases life span robustly under all conditions tested; however, deletion of hif-1 increases life span in a temperature-dependent manner.

  10. Data show that that reactive oxygen species (ROS (show ROS1 Antibodies)) are increased in respiration mutants and that mild increases in ROS (show ROS1 Antibodies) can stimulate HIF-1 to activate gene expression and promote longevity.

Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) Antigen Profile

Antigen Summary

This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Alternative names and synonyms associated with Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A)

  • hypoxia inducible factor 1 alpha (hif-1a) antibody
  • hypoxia inducible factor 1, alpha subunit (Hif1a) antibody
  • hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (HIF1A) antibody
  • hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (Hif1a) antibody
  • hypoxia-inducible factor 1 alpha (hif-1a) antibody
  • hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (Hif1a) antibody
  • Protein HIF-1 (hif-1) antibody
  • AA959795 antibody
  • bHLHe78 antibody
  • hif-1a antibody
  • HIF-1alpha antibody
  • HIF1 antibody
  • HIF1-alpha antibody
  • hif1a antibody
  • HIF1alpha antibody
  • MOP1 antibody
  • PASD8 antibody

Protein level used designations for HIF1A

HIF-1 alpha , HIF-1-alpha , HIF1 alpha , HIF1-alpha , Hypoxia-inducible factor 1 alpha , hypoxia-inducible factor 1-alpha , ARNT-interacting protein , ARNT interacting protein , PAS domain-containing protein 8 , basic-helix-loop-helix-PAS protein MOP1 , class E basic helix-loop-helix protein 78 , hypoxia-inducible factor 1 alpha isoform I.3 , hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) , hypoxia-inducible factor1alpha , member of PAS protein 1 , member of PAS superfamily 1 , hypoxia-inducible factor 1 alpha , hypoxia inducible factor 1 alpha subunit , hypoxia inducible factor 1, alpha subunit

GENE ID SPECIES
100337573 Xenopus laevis
15251 Mus musculus
3091 Homo sapiens
396696 Sus scrofa
281814 Bos taurus
101692645 Mustela putorius furo
443519 Ovis aries
100009579 Oryctolagus cuniculus
480348 Canis lupus familiaris
100713113 Cavia porcellus
374177 Gallus gallus
100135944 Oncorhynchus mykiss
29560 Rattus norvegicus
180359 Caenorhabditis elegans
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