CPE Protein (His tag)
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- Target See all CPE Proteins
- CPE (Carboxypeptidase E (CPE))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CPE protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product CPE Protein
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- Comment
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Synonyms: Carboxypeptidase E, Carboxypeptidase H, CPH
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- CPE (Carboxypeptidase E (CPE))
- Alternative Name
- CPE (CPE Products)
- Synonyms
- CPE Protein, CPH Protein, Cph-1 Protein, Cph1 Protein, R74677 Protein, fat Protein, CARBE Protein, Cph Protein, si:ch211-198g9.2 Protein, zgc:85981 Protein, carboxypeptidase E Protein, carboxypeptidase E L homeolog Protein, CPE Protein, cpe Protein, Cpe Protein, cpe.L Protein
- Background
- CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but constitutively secreted proteins. Mutations in CPE are implicated in type II diabetes. Recombinant human CPE protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 51.4 kDa (457aa)
- NCBI Accession
- NP_001864
- Pathways
- Peptide Hormone Metabolism, Synaptic Membrane
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