Ephrin A3 Protein (EFNA3) (AA 23-213) (Fc Tag)
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- Target See all Ephrin A3 (EFNA3) Proteins
- Ephrin A3 (EFNA3)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-213
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Ephrin A3 protein is labelled with Fc Tag.
- Sequence
- AA 23-213
- Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product EFNA3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- Ephrin A3 (EFNA3)
- Alternative Name
- Ephrin-A3 (EFNA3 Products)
- Synonyms
- efna3 Protein, D160 Protein, ephrin-A3 Protein, zgc:100772 Protein, AW494418 Protein, EFL-2 Protein, Ehk1-L Protein, Epl3 Protein, LERK-3 Protein, MGC64593 Protein, EFL2 Protein, EPLG3 Protein, LERK3 Protein, ephrin A3 Protein, ephrin-A3b Protein, ephrin A3 L homeolog Protein, efna3 Protein, EFNA3 Protein, efna3b Protein, Efna3 Protein, efna3.L Protein
- Background
- Ephrin-A3 (Ephrin A3) is also known as EFL-2, EHK1 ligand, EHK1-L, EPH-related receptor tyrosine kinase ligand 3, EFL2, EPLG3 and LERK3,which comprises the largest subfamily of receptor protein-tyrosine kinases (RTKs), and has been involved in a variety of biological processes, especially in the nervous system and in erythropoiesis, such as axon guidance and topographic map formation, synaptic plasticity, angiogenesis, and meanwhile have possible contributions to tumor growth and metastasis. Ephrin A3 is cell surface GPI-bound ligand for Eph receptors and belongs to the family of receptor tyrosine kinases. Ephrin can bind promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.
- Molecular Weight
- 48 kDa
- Pathways
- RTK Signaling
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