Ephrin A3 Protein (EFNA3) (His tag)

Catalog No. ABIN7536306

Product Details

Target: Ephrin A3 (EFNA3)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Ephrin A3 protein is labelled with His tag.

Purpose: Recombinant human Ephrin-A3/EFNA3 Protein

Sequence: MAAAPLLLLL LLVPVPLLPL LAQGPGGALG NRHAVYWNSS NQHLRREGYT VQVNVNDYLD IYCPHYNSSG VGPGAGPGPG GGAEQYVLYM VSRNGYRTCN ASQGFKRWEC NRPHAPHSPI KFSEKFQRYS AFSLGYEFHA GHEYYYISTP THNLHWKCLR MKVFVCCAST SHSGEKPVPT LPQFTMGPNV KINVLEDFEG ENPQVPKLEK SIS

Specificity: Met 1-Ser 213

Sterility: 0.22 μm filtered

Endotoxin Level: < 0.01EU/μg

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Concentration: 0.85 mg/mL

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Target Details

Target: Ephrin A3 (EFNA3)

Alternative Name: Ephrin-A3/EFNA3 (EFNA3 Products)

Synonyms: efna3 Protein, D160 Protein, ephrin-A3 Protein, zgc:100772 Protein, AW494418 Protein, EFL-2 Protein, Ehk1-L Protein, Epl3 Protein, LERK-3 Protein, MGC64593 Protein, EFL2 Protein, EPLG3 Protein, LERK3 Protein, ephrin A3 Protein, ephrin-A3b Protein, ephrin A3 L homeolog Protein, efna3 Protein, EFNA3 Protein, efna3b Protein, Efna3 Protein, efna3.L Protein

Background:

Description: Ephrin-A3 (Ephrin A3) is also known as EFL-2, EHK1 ligand, EHK1-L, EPH-related receptor tyrosine kinase ligand 3, EFL2, EPLG3 and LERK3,which comprises the largest subfamily of receptor protein-tyrosine kinases (RTKs), and has been involved in a variety of biological processes, especially in the nervous system and in erythropoiesis, such as axon guidance and topographic map formation, synaptic plasticity, angiogenesis, and meanwhile have possible contributions to tumor growth and metastasis. Ephrin A3 is cell surface GPI-bound ligand for Eph receptors and belongs to the family of receptor tyrosine kinases. Ephrin can bind promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.

Name: EFL2, EPLG3, LERK3, Ehk1-L,EFNA3

Gene ID: 1944

UniProt: P52797-1

Pathways: RTK Signaling