NCR1 Protein (AA 22-254) (Fc Tag)
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- Target See all NCR1 Proteins
- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-254
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NCR1 protein is labelled with Fc Tag.
- Sequence
- AA 22-254
- Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 53 kDa. The protein migrates as 53-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product NCR1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
- Alternative Name
- NKp46 (NCR1 Products)
- Synonyms
- CD335 Protein, LY94 Protein, NK-p46 Protein, NKP46 Protein, Ly94 Protein, NKp46 Protein, KILR-1 Protein, Nk-p46 Protein, Nkp46 Protein, natural cytotoxicity triggering receptor 1 Protein, NCR1 Protein, Ncr1 Protein
- Background
- Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
- Molecular Weight
- 53.0 kDa
- Pathways
- Regulation of Leukocyte Mediated Immunity
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