INSL3 Protein (His tag)

Catalog No. ABIN2723494

Product Details

Target: INSL3 (Insulin-Like 3 (Leydig Cell) (INSL3))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This INSL3 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human INSL3 / RLF protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin Level: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM PB,150 mM NaCl, pH 7.4

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: INSL3 (Insulin-Like 3 (Leydig Cell) (INSL3))

Alternative Name: Insl3,rlf (INSL3 Products)

Synonyms: INSL3 Protein, Rlf Protein, Rlnl Protein, RLF Protein, RLNL Protein, ley-I-L Protein, BLEYI-L Protein, LEY I-L Protein, Ley-I-L Protein, insulin like 3 Protein, insulin-like 3 Protein, Janus kinase 3 Protein, INSL3 Protein, Insl3 Protein, JAK3 Protein

Background: This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants.

Molecular Weight: 13.4kD

NCBI Accession: NP_005534

Pathways: Hormone Activity, cAMP Metabolic Process