INSL3 Protein (His tag)
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- Target See all INSL3 Proteins
- INSL3 (Insulin-Like 3 (Leydig Cell) (INSL3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This INSL3 protein is labelled with His tag.
- Purpose
- Recombinant Human INSL3 Protein (His Tag)
- Sequence
- Leu21-Tyr131
- Characteristics
- Recombinant Human Insulin-like 3 is produced by our Mammalian expression system and the target gene encoding Leu21-Tyr131 is expressed with a 6His tag at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product INSL3 Protein
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Insulin-Like 3 (Leydig Cell) (INSL3) protein (Myc-DYKDDDDK Tag)
INSL3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- INSL3 (Insulin-Like 3 (Leydig Cell) (INSL3))
- Alternative Name
- INSL3 (INSL3 Products)
- Synonyms
- INSL3 Protein, Rlf Protein, Rlnl Protein, RLF Protein, RLNL Protein, ley-I-L Protein, BLEYI-L Protein, LEY I-L Protein, Ley-I-L Protein, insulin like 3 Protein, insulin-like 3 Protein, Janus kinase 3 Protein, INSL3 Protein, Insl3 Protein, JAK3 Protein
- Background
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Background: Insulin-like 3 is a protein that in humans is encoded by the INSL3 gene. It is a secreted protein that belongs to the insulin family. It is expressed in prenatal and postnatal Leydig cells and found as well in the corpus luteum, trophoblast, fetal membranes and breast. It may act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent.It is a ligand for LGR8 receptor.
Synonym: Insulin-like 3, Leydig insulin-like peptide, Relaxin-like factor, INSL3, RLF, RLNL
- Molecular Weight
- 13.4 kDa
- UniProt
- P51460
- Pathways
- Hormone Activity, cAMP Metabolic Process
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