PIK3 gamma Protein (Myc-DYKDDDDK Tag)
-
- Target See all PIK3 gamma (PIK3CG) Proteins
- PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PIK3 gamma protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human PIK3CG protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
Cilostazol Induces PGI2 Production via Activation of the Downstream Epac-1/Rap1 Signaling Cascade to Increase Intracellular Calcium by PLC? and to Activate p44/42 MAPK in Human Aortic Endothelial ..." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132835, (2015) (PubMed).
: "
-
Cilostazol Induces PGI2 Production via Activation of the Downstream Epac-1/Rap1 Signaling Cascade to Increase Intracellular Calcium by PLC? and to Activate p44/42 MAPK in Human Aortic Endothelial ..." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132835, (2015) (PubMed).
-
- Target
- PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
- Alternative Name
- Pik3cg (PIK3CG Products)
- Synonyms
- PI3CG Protein, PI3K Protein, PI3Kgamma Protein, PIK3 Protein, Pi3k Protein, wu:fb15d07 Protein, zgc:77033 Protein, pi3k Protein, 5830428L06Rik Protein, p110gamma Protein, p120-PI3K Protein, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Protein, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma Protein, si:rp71-17i16.5 Protein, PIK3CG Protein, Pik3cg Protein, pik3cg Protein, si:rp71-17i16.5 Protein
- Background
- Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.
- Molecular Weight
- 126.3 kDa
- NCBI Accession
- NP_002640
- Pathways
- PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, TLR Signaling, Inositol Metabolic Process, Hepatitis C, VEGF Signaling
-