SMAD4 Protein (AA 1-552) (His tag)
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- Target See all SMAD4 Proteins
- SMAD4 (SMAD Family Member 4 (SMAD4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-552
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SMAD4 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- SMAD4, 1-552aa, Human,His tagged, Recombinant, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SMAD4 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol
- Storage
- 4 °C
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- Target
- SMAD4 (SMAD Family Member 4 (SMAD4))
- Alternative Name
- SMAD4 (SMAD4 Products)
- Synonyms
- smad4 Protein, DPC4 Protein, JIP Protein, MADH4 Protein, MYHRS Protein, AW743858 Protein, D18Wsu70e Protein, Madh4 Protein, XSmad4alpha Protein, Xsmad4 Protein, dpc4 Protein, jip Protein, madh4 Protein, xsmad4a Protein, SMAD family member 4 Protein, Smad4 protein Protein, SMAD family member 4, gene 1 L homeolog Protein, SMAD4 Protein, smad4 Protein, Smad4 Protein, smad4.1.L Protein
- Background
- SMAD4 belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD4 promotes the binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides the function of activation required for SMAD1 or SMAD2 to stimulate transcription and may also act as a tumor suppressor. Recombinant SMAD4 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Mothers against decapentaplegic homolog 4, SMAD family member 4, DPC4, JIP, MADH4, SMAD4 , Mothers against decapentaplegic homolog 4 (Small) Mothers Against Decapentaplegic, Deleted in Pancreatic Carcinoma, Deleted in pancreatic carcinoma locus 4, Deletion target in pancreatic carcinoma 4, DPC 4, MAD mothers against decapentaplegic Drosophila homolog 4, hSMAD4, MAD homolog 4, MAD mothers against decapentaplegic homolog 4, MADH 4, Med, Medea, Mothers against DPP homolog 4, OTTHUMP00000163548, Smad 4, SMAD mothers against DPP homolog 4. NCBI no.: NP_005350
- Molecular Weight
- 62.6 kDa (572 aa)
- Pathways
- Cell Division Cycle, Chromatin Binding, Autophagy
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