FLIP Protein (AA 1-480)
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- Target See all FLIP (CFLAR) Proteins
- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-480
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Characteristics
- CFLAR, 1-480aa, Human, E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product CFLAR Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol
- Storage
- 4 °C
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- Target
- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
- Alternative Name
- CFLAR (CFLAR Products)
- Synonyms
- Clarp1 Protein, cflar Protein, CFLAR Protein, FLIP Protein, CASH Protein, CASP8AP1 Protein, CLARP Protein, Casper Protein, FLAME Protein, FLAME-1 Protein, FLAME1 Protein, I-FLICE Protein, MRIT Protein, c-FLIP Protein, c-FLIPL Protein, c-FLIPR Protein, c-FLIPS Protein, 2310024N18Rik Protein, A430105C05Rik Protein, Cash Protein, ENSMUSG00000072980 Protein, Flip Protein, Gm9845 Protein, c-Flip Protein, CASP8 and FADD-like apoptosis regulator a Protein, CASP8 and FADD like apoptosis regulator Protein, CASP8 and FADD like apoptosis regulator S homeolog Protein, CASP8 and FADD-like apoptosis regulator Protein, cflara Protein, CFLAR Protein, cflar Protein, cflar.S Protein, Cflar Protein
- Background
- CFLAR, also known as FLIP, is involved in the regulation of apoptosis. It has been designated by independent groups as Casper, I-FLICE, CLARP, FLAME-1 and MRIT. Although its exact role is still being elucidated, it appears to be an important factor in the regulation of apoptosis downstream of all known death receptors. Recombinant human CFLAR protein was expressed in E.coli and denatured using detergent during a conventional chromatography purification process. Synonyms: CASP8 and FADD-like apoptosis regulator, CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, USURPIN. NCBI no.: NP_003870
- Molecular Weight
- 55.3 kDa (480aa)
- Pathways
- Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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