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IL-11 Protein

IL11 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Catalog No. ABIN935575
  • Target See all IL-11 (IL11) Proteins
    IL-11 (IL11) (Interleukin 11 (IL11))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 18
    • 11
    • 2
    • 2
    Mouse
    Source
    • 13
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    MPGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPADGDH SLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW LRRAGGPSLK TLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGS IRAAHAILGG LHLTLDWAVR GLLLLKTRL
    Characteristics
    Purified recombinant Mouse IL11 protein
    Expression System: E.coli
    Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse T11 cells is ? 2.0 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg.
    Purity
    > 98 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product IL11 Protein
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    RT/-20 °C
  • Target
    IL-11 (IL11) (Interleukin 11 (IL11))
    Alternative Name
    IL11 (IL11 Products)
    Synonyms
    IL11 Protein, AGIF Protein, IL-11 Protein, Il-11 Protein, interleukin 11 Protein, IL11 Protein, Il11 Protein
    Background
    IL11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury.
    Alternative Names: Interleukin 11 protein, AGIF protein, IL 11 protein, IL-11 protein, IL-11 protein, IL11, IL-11, Adipogenesis inhibitory factor protein, IL 11
    Molecular Weight
    19.1 kDa
    Pathways
    JAK-STAT Signaling, Negative Regulation of Hormone Secretion
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