Cytokeratins in the detection of tumors
Cytokeratins (CKs, or following more recent nomenclature also simply called keratins) are intermediate filament?forming proteins that provide mechanical support and fulfill a variety of additional functions in epithelial cells. They are part of the cytoskeleton and the largest family of intermediate filament proteins. Two types of Cytokeratins are distinguished that form heterodimers, namely acidic type I (Cytokeratins 9-23) and basic type II (Cytokeratins 1-8).
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