anti-Human FLT4 antibody for Enzyme Immunoassay

Recommended FLT4 Antibody (supplied by: Log in to see )

Antigen
Fms-Related Tyrosine Kinase 4 (FLT4) Antibodies
  • AI323512
  • Chy
  • Flt-4
  • VEGFR-3
  • VEGFR3
  • FLT41
  • LMPH1A
  • PCL
  • Vegfr3
  • cb1059
  • 6130401C07
  • Flk-1
  • Flk1
  • Krd-1
  • Ly73
  • VEGFR-2
  • VEGFR2
  • sVEGFR-2
  • FMS-like tyrosine kinase 4
  • fms-related tyrosine kinase 4
  • kinase insert domain protein receptor
  • Flt4
  • FLT4
  • flt4
  • Kdr
Epitope
Extracellular Domain
30
21
16
15
14
12
11
10
9
9
7
7
6
3
2
1
1
1
1
1
1
Reactivity
Human
202
136
47
Host
Mouse
126
96
48
14
1
Clonality
Monoclonal
Conjugate
This FLT4 antibody is un-conjugated
21
12
8
8
7
6
5
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
176
106
91
75
65
27
26
23
11
8
6
5
5
3
3
3
3
2
2
1
1
Supplier
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Catalog No. ABIN567981
$ 412.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN115161 EIA IHC (fro) IHC (p) WB Mouse IgG1 Extracellular Domain Log in to see (3C3) 9D9 2
1 ABIN115160 EIA WB Biotin Mouse IgG1 Extracellular Domain Log in to see 3C3 2
1 ABIN356407 EIA IHC (p) WB Mouse IgG1 Log in to see 44CT92-4-4
1 ABIN1109477 EIA WB Mouse IgG1 Log in to see 4H4 2
1 ABIN155187 EIA IP WB Rabbit Log in to see Polyclonal
1 ABIN155186 EIA IP WB Rabbit Log in to see Polyclonal
1 ABIN115685 EIA IP WB Rabbit Log in to see Polyclonal
1 ABIN2735240 EIA Rabbit IgG Log in to see Polyclonal

General

Antigen Fms-Related Tyrosine Kinase 4 (FLT4) Antibodies
Epitope Extracellular Domain
(30), (21), (16), (15), (14), (12), (11), (10), (9), (9), (7), (7), (6), (3), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(202), (136), (47)
Host Mouse
(126), (96), (48), (14), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FLT4 antibody is un-conjugated
(21), (12), (8), (8), (7), (6), (5), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(176), (106), (91), (75), (65), (27), (26), (23), (11), (8), (6), (5), (5), (3), (3), (3), (3), (2), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-FLT4 Antibody

Target Details FLT4 Application Details Handling References for anti-FLT4 antibody (ABIN567981) Images
Specificity This antibody detects Human VEGFR-3/FLT-4. Other species not tested.
Purification Affinity Chromatography on Protein G.
Immunogen Recombinant Human Vascular Endothelial Growth Factor Receptor 3 (rh VEGFR-3/FLT-4) extracellular domain
Clone 2-00E-011
Isotype IgG1

Target Details FLT4

Product Details anti-FLT4 Antibody Application Details Handling References for anti-FLT4 antibody (ABIN567981) Images back to top
Antigen
Alternative Name VEGFR-3 / Flt-4 (FLT4 Antibody Abstract)
Background VEGFR-1 (Flt-1), VEGFR-2 (KDR/Flk 1) and VEGFR-3 (FLT-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domains and kinase insert domains in their intracellular regions. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular and lymphatic endothelial cells and to the monocyte/macrophage lineage. These receptors play essential roles in vasculogenesis, hematopoiesis, angiogenesis and lymphangiogenesis. The VEGFR-3 cDNA encodes a 1298 amino acid (aa) residue precursor protein with a 24 aa residue signal peptide. Mature VEGFR-3 is composed of a 751 aa residue extracellular domain, a 22 aa residue transmembrane domain and a 482 aa residue cytoplasmic domain. Both VEGF-C and VEGF-D have been shown to bind and activate VEGF R3 (Flt-4). The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stage of development. It is important for lymphangiogenesis.Synonyms: FLT4, Tyrosine-protein kinase receptor FLT4, VEGF Receptor 3, VEGFR3, Vascular endothelial growth factor receptor 3
Gene ID 2324
NCBI Accession NP_002011
UniProt P35916
Research Area Cytokines, Receptors
Pathways RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling

Application Details

Product Details anti-FLT4 Antibody Target Details FLT4 Handling References for anti-FLT4 antibody (ABIN567981) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-FLT4 Antibody Target Details FLT4 Application Details References for anti-FLT4 antibody (ABIN567981) Images back to top
Reconstitution Restore in Sterile water to a concentration of 0.1-1.0 mg/mL
Concentration 0.5 mg/mL
Buffer PBS, pH 7.4 without preservatives
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C for 6 month or at -20 °C for longer. Following reconstitution store the antibody undiluted at 2-8 °C for one month.
Expiry Date 6 months

References for anti-FLT4 antibody (ABIN567981)

Product Details anti-FLT4 Antibody Target Details FLT4 Application Details Handling Images back to top
Background publications

Jussila, Valtola, Partanen, Salven, Heikkilä, Matikainen, Renkonen, Kaipainen, Detmar, Tschachler, Alitalo, Alitalo: "Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3." in: Cancer research, Vol. 58, Issue 8, pp. 1599-604, 1998

Images

Product Details anti-FLT4 Antibody Target Details FLT4 Application Details Handling References for anti-FLT4 antibody (ABIN567981) back to top
Supplier Images
Enzyme Immunoassay (EIA) image for anti-Fms-Related Tyrosine Kinase 4 (FLT4) (Extracellular Domain) antibody (ABIN567981) Sandwich-ELISA using recombinant human soluble FLT-4 as standard . Mouse anti-Human F...
Western Blotting (WB) image for anti-Fms-Related Tyrosine Kinase 4 (FLT4) (Extracellular Domain) antibody (ABIN567981) Western analysis of recombinant human soluble VEGFR3/FLT-4 using a Mouse anti-Human F...