anti-Rat (Rattus) GRB2 antibody for Immunohistochemistry

Recommended GRB2 Antibody (supplied by: Log in to see )

Antigen
Growth Factor Receptor-Bound Protein 2 (GRB2) Antibodies
  • GRB2
  • grb2
  • AA408164
  • Ash
  • ASH
  • EGFRBP-GRB2
  • Grb3-3
  • MST084
  • MSTP084
  • NCKAP2
  • wu:fb18e12
  • wu:fb34e06
  • zgc:73077
  • growth factor receptor-bound protein 2
  • Growth factor receptor-bound protein 2
  • growth factor receptor bound protein 2
  • growth factor receptor-bound protein 2b
  • GRB2
  • grb2
  • Grb2
  • LOC100342500
  • grb2b
Epitope
AA 125-174, pSer159
34
16
10
8
7
6
6
5
5
5
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
160
63
63
16
10
9
7
5
4
4
3
3
3
3
3
2
2
1
1
Host
Rabbit
107
27
25
2
Clonality
Polyclonal
Conjugate
This GRB2 antibody is un-conjugated
8
4
3
3
3
3
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
144
69
54
31
13
7
5
4
2
2
2
1
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Catalog No. ABIN1532105
$ 302.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
9.452184 ABIN257708 ELISA IHC IHC (p) WB Goat C-Term, both Isoforms Log in to see Polyclonal 1
1 ABIN967755 BI IP IHC WB Mouse IgG1 AA 1-217 Log in to see 81-GRB2 5
1 ABIN967754 BI IP IHC WB Mouse IgG1 AA 1-217 Log in to see 81-GRB2 5
1 ABIN1876890 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2562931 IHC ELISA WB Goat IgG C-Term Log in to see Polyclonal
1 ABIN2881227 IF IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2406480 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2886967 IHC WB Rabbit Log in to see Polyclonal
1 ABIN2976206 IF/ICC IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2418221 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1576856 IHC ELISA WB Rabbit pSer159 Log in to see Polyclonal
1 ABIN1847698 IHC ELISA WB Rabbit Internal Region, pSer159, pSer160 Log in to see Polyclonal

General

Antigen Growth Factor Receptor-Bound Protein 2 (GRB2) Antibodies
Epitope AA 125-174, pSer159
(34), (16), (10), (8), (7), (6), (6), (5), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(160), (63), (63), (16), (10), (9), (7), (5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (1), (1)
Host Rabbit
(107), (27), (25), (2)
Clonality
Polyclonal
Conjugate This GRB2 antibody is un-conjugated
(8), (4), (3), (3), (3), (3)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(144), (69), (54), (31), (13), (7), (5), (4), (2), (2), (2), (1)
Pubmed 2 references available
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Product Details anti-GRB2 Antibody

Target Details GRB2 Application Details Handling References for anti-GRB2 antibody (ABIN1532105) Images
Specificity

GRB2 (Phospho-Ser159) Antibody detects endogenous levels of GRB2 only when phosphorylated at Ser159.

PhosphorylationH:S159 M:S160 R:S160

Purification The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Purity > 95 %
Immunogen The antiserum was produced against synthesized peptide derived from human GRB2 around the phosphorylation site of Ser159.
Isotype IgG

Target Details GRB2

Product Details anti-GRB2 Antibody Application Details Handling References for anti-GRB2 antibody (ABIN1532105) Images back to top
Antigen
Alternative Name GRB2 (GRB2 Antibody Abstract)
Background

Synonyms: GRB2-associated-binding protein 2, Growth factor receptor bound protein 2-associated protein 2, GRB2-associated binder 2, pp100, KIAA0571

NCBI Gene Symbol: GAB2

Molecular Weight 74 kDa
Gene ID 9846
OMIM 606203
UniProt Q9UQC2
Research Area Cancer
Pathways RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation

Application Details

Product Details anti-GRB2 Antibody Target Details GRB2 Handling References for anti-GRB2 antibody (ABIN1532105) Images back to top
Application Notes WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000
Comment

Unigene-Number: Hs.429434 (NCBI Gene Symbol: GAB2)

Restrictions For Research Use only

Handling

Product Details anti-GRB2 Antibody Target Details GRB2 Application Details References for anti-GRB2 antibody (ABIN1532105) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Stable at -20°C for at least 1 year.
Expiry Date 12 months

References for anti-GRB2 antibody (ABIN1532105)

Product Details anti-GRB2 Antibody Target Details GRB2 Application Details Handling Images back to top
Background publications

Taylor, Noguchi, Totoki, Toyoda, Kuroki, Dewar, Lloyd, Itoh, Takeda, Kim, She, Barlow, Bloom, Bruford, Chang, Cuomo, Eichler, FitzGerald, Jaffe, LaButti, Nicol, Park, Seaman, Sougnez, Yang, Zimmer et al.: "Human chromosome 11 DNA sequence and analysis including novel gene identification. ..." in: Nature, Vol. 440, Issue 7083, pp. 497-500, 2006

Nishida, Yoshida, Itoh, Fukada, Ohtani, Shirogane, Atsumi, Takahashi-Tezuka, Ishihara, Hibi, Hirano: "Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors." in: Blood, Vol. 93, Issue 6, pp. 1809-16, 1999

Images

Product Details anti-GRB2 Antibody Target Details GRB2 Application Details Handling References for anti-GRB2 antibody (ABIN1532105) back to top
Supplier Images
Western Blotting (WB) image for anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (AA 125-174), (pSer159) antibody (ABIN1532105) Western blot analysis of extracts from HT29 cells treated with serum 20% 15', using G...
Immunohistochemistry (IHC) image for anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (AA 125-174), (pSer159) antibody (ABIN1532105) Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using GRB2 ...