Browse our anti-HBEGF (HBEGF) Antibodies

Full name:
anti-Heparin-Binding EGF-Like Growth Factor Antibodies (HBEGF)
On www.antibodies-online.com are 76 Heparin-Binding EGF-Like Growth Factor (HBEGF) Antibodies from 18 different suppliers available. Additionally we are shipping HBEGF Kits (57) and HBEGF Proteins (29) and many more products for this protein. A total of 168 HBEGF products are currently listed.
Synonyms:
AW047313, Dtr, Dts, DTSF, GFHB, HB-EGF, HBEGF, Hegfl, zgc:165443, zgc:175091
list all antibodies Gene Name GeneID UniProt
HBEGF 1839 Q99075
HBEGF 25433 Q06175
HBEGF 15200 Q06186

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anti-Rat (Rattus) HBEGF Antibodies:

anti-Mouse (Murine) HBEGF Antibodies:

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Top referenced anti-HBEGF Antibodies

  1. Human Monoclonal HBEGF Primary Antibody for ICC, IF - ABIN2451994 : Prenzel, Zwick, Daub, Leserer, Abraham, Wallasch, Ullrich: EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. in Nature 2000 (PubMed)
    Show all 4 references for 2451994

  2. Human Monoclonal HBEGF Primary Antibody for ICC, IF - ABIN3201018 : Miyamoto, Hirata, Yamazaki, Kageyama, Hasuwa, Mizushima, Tanaka, Yagi, Sonoda, Kai, Kanoh, Nakano, Mekada: Heparin-binding EGF-like growth factor is a promising target for ovarian cancer therapy. in Cancer research 2004 (PubMed)
    Show all 4 references for 3201018

  3. Human Polyclonal HBEGF Primary Antibody for EIA, WB - ABIN952685 : Rahman, Kadowaki, Ishihara, Tobita, Imaoka, Fukuhara, Aziz, Furuta, Amano, Kinoshita: Fibroblast-derived HB-EGF promotes Cdx2 expression in esophageal squamous cells. in Laboratory investigation; a journal of technical methods and pathology 2010 (PubMed)
    Show all 4 references for 952685

  4. Human Polyclonal HBEGF Primary Antibody for WB - ABIN658749 : Hamaoka, Chinen, Murata, Takashima, Iwamoto, Mekada: Anti-human HB-EGF monoclonal antibodies inhibiting ectodomain shedding of HB-EGF and diphtheria toxin binding. in Journal of biochemistry 2010 (PubMed)

  5. Human Monoclonal HBEGF Primary Antibody for FACS - ABIN4897711 : Mandl, Drechsler, Jansen, Neideck, Noels, Faussner, Soehnlein, Weber, Döring: Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation. in PLoS ONE 2015 (PubMed)

  6. Human Polyclonal HBEGF Primary Antibody for IF (p), IHC (p) - ABIN701050 : Lebkuechner, Wilhelmsson, Möllerström, Pekna, Pekny: Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency. in Journal of neurochemistry 2015 (PubMed)

More Antibodies against HBEGF Interaction Partners

Zebrafish Heparin-Binding EGF-Like Growth Factor (HBEGF) interaction partners

  1. These results suggest that there is an EGF (show EGF Antibodies) signaling network in the zebrafish ovarian follicle, and the functionality of this network is self-regulated by its own members.

Human Heparin-Binding EGF-Like Growth Factor (HBEGF) interaction partners

  1. Results show that HBEGF is highly expressed in primary ovarian tumors and increases as the disease progresses.

  2. Serous carcinomatous component championed by expression of HB-EGF predisposes to recurrence/metastasis in stage I metastasis and recurrence in stage I uterine malignant mixed mullerian tumor.

  3. Annexin A2 (show ANXA2 Antibodies) and HB-EGF are overexpressed and are being secreted into serum in Her-2 (show ERBB2 Antibodies) negative breast cancer patients.

  4. Study demonstrates that HBEGF is post-transcriptionally regulated by low O2 (placental environment) through a mechanism involving interactions of miRNAs with its 3'UTR (show UTS2R Antibodies).

  5. MMP14 (show MMP14 Antibodies) plays an important mechanistic role in NSCLC progression, by supporting cancer invasiveness, promoting collagen degradation, and releasing HB-EGF, which accelerates lung tumor progression.

  6. These results indicate that this new anti-HB-EGF mAb 2-108 would be useful in the diagnosis of HB-EGF-related cancers and would be a strong tool in both basic and clinical research on HB-EGF.

  7. This antibody reacts with human HB-EGF but not mouse HB-EGF. No cross-reactivity to other EGFR (show EGFR Antibodies) ligands was observed by antigen ELISA.

  8. HB-EGF is a molecular target for the resistance of ovarian cancer to paclitaxel and CRM197 as a HB-EGF-targeted agent might be a chemosensitizing agent for paclitaxel-resistant ovarian carcinoma

  9. Data suggest that placental expression of HBEGF, EGF (show EGF Antibodies) (epidermal GF), and TGFA (show TGFA Antibodies) (transforming GF alpha) is down-regulated in pre-eclampsia as compared to normal term birth; each growth factor blocks cell death/apoptosis of cytotrophoblast cell line.

  10. Serum sHB (show SHB Antibodies)-EGF (show EGF Antibodies) is closely correlated with advanced stage gastric cancer and can be a promising serological biomarker for GC.

Mouse (Murine) Heparin-Binding EGF-Like Growth Factor (HBEGF) interaction partners

  1. These results indicate that ATX (show ENPP2 Antibodies)-lysophosphatidic acid-LPA3 (show LPAR3 Antibodies) signaling at the embryo-epithelial boundary induces decidualization via the canonical HB-EGF and COX-2 (show COX2 Antibodies) pathways.

  2. our results suggest that shedding of HB-EGF from endothelium plays an important role in Ang II (show AGT Antibodies)-induced renal injury by linking Ang II (show AGT Antibodies)-AT1R (show AGTRAP Antibodies) with EGFR (show EGFR Antibodies) transactivation.

  3. Results suggest that HB-EGF secreted from KRas-mutated colorectal cancer cells promotes intestinal myofibroblasts migration through ERK (show EPHB2 Antibodies) and JNK (show MAPK8 Antibodies) activation, which, in turn, could support cancer progression.

  4. this study revealed that HB-EGF as well as HGF (show HGF Antibodies) inhibited BDL-induced cholestatic liver injury by predominantly exerting acute cytoprotective and chronic antifibrotic effects, respectively.

  5. Abnormal keratinocyte migration and down-regulated expression of the Hbegf gene might be associated with impaired eyelid development in B6-Co mice.

  6. Pelvic irradiation increases versican (show Vcan Antibodies) expression in bladder and rectum.

  7. Psychiatric, social-behavioral and cognitive abnormalities were also observed in hippocampal Hbegf knockout mice.

  8. HB-EGF promotes enteric neural stem cell proliferation and migration in a mouse model

  9. mice in which DTR is expressed on conventional Dendritic cells display marked lymph node hypocellularity and reduced frequency of Dendritic cells in the same organs but not in spleen or nonlymphoid tissues.

  10. miR (show MLXIP Antibodies)-96 promotes osteogenic differentiation by inhibiting HB-EGF and by blocking the HB-EGF-EGFR (show EGFR Antibodies) signaling pathway in osteoblastic cells

Cow (Bovine) Heparin-Binding EGF-Like Growth Factor (HBEGF) interaction partners

  1. These results indicate that HB-EGF and its receptors expression changed in bovine endometrium throughout the oestrous cycle; IFN-tau increased their expression in cultured endometrial cells.

  2. Heparin-binding EGF-like growth factor is main component in chromaffin granules responsible for neurotrophic effect on dopaminergic neurones. Protective effects on nigrostriatal dopaminergic neurones. Candidate for treatment of Parkinson's disease.

HBEGF Antigen Profile

Antigen Summary

Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

Alternative names and synonyms associated with HBEGF

  • heparin-binding EGF-like growth factor b (hbegfb) antibody
  • heparin-binding EGF-like growth factor (HBEGF) antibody
  • Heparin-binding EGF-like growth factor (hbegf) antibody
  • heparin-binding EGF-like growth factor a (hbegfa) antibody
  • heparin-binding EGF-like growth factor (LOC100232539) antibody
  • heparin-binding EGF-like growth factor (Hbegf) antibody
  • heparin-binding epidermal growth factor (LOC100008809) antibody
  • AW047313 antibody
  • Dtr antibody
  • Dts antibody
  • DTSF antibody
  • GFHB antibody
  • HB-EGF antibody
  • HBEGF antibody
  • Hegfl antibody
  • zgc:165443 antibody
  • zgc:175091 antibody

Protein level used designations for HBEGF

proheparin-binding EGF-like growth factor , heparin-binding EGF-like growth factor , Heparin-binding EGF-like growth factor , diphtheria toxin receptor (heparin-binding EGF-like growth factor) , diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor) , heparin-binding epidermal growth factor , Diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor) , heparin binding epidermal growth factor-like growth factor , heparin-binding epidermal -growth - like growth factor , heparin-binding epidermal -growth factor , diphtheria toxin receptor , heparin-binding epidermal growth factor-like growth factor

GENE ID SPECIES
407664 Danio rerio
695559 Macaca mulatta
735979 Pan troglodytes
100305262 Oncorhynchus mykiss
607007 Canis lupus familiaris
797938 Danio rerio
100232539 Taeniopygia guttata
1839 Homo sapiens
25433 Rattus norvegicus
15200 Mus musculus
395654 Gallus gallus
397564 Sus scrofa
522921 Bos taurus
100008809 Oryctolagus cuniculus
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