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Browse our anti-HBEGF (HBEGF) Antibodies

Full name:
anti-Heparin-Binding EGF-Like Growth Factor Antibodies (HBEGF)
On are 62 Heparin-Binding EGF-Like Growth Factor (HBEGF) Antibodies from 14 different suppliers available. Additionally we are shipping HBEGF Kits (67) and HBEGF Proteins (31) and many more products for this protein. A total of 164 HBEGF products are currently listed.
AW047313, Dtr, Dts, DTSF, GFHB, HB-EGF, HBEGF, Hegfl, zgc:165443, zgc:175091
list all antibodies Gene Name GeneID UniProt
HBEGF 1839 Q99075
HBEGF 25433 Q06175
HBEGF 15200 Q06186

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anti-Human HBEGF Antibodies:

anti-Rat (Rattus) HBEGF Antibodies:

anti-Mouse (Murine) HBEGF Antibodies:

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Top referenced anti-HBEGF Antibodies

  1. Human Monoclonal HBEGF Primary Antibody for ICC, IF - ABIN3201018 : Prenzel, Zwick, Daub, Leserer, Abraham, Wallasch, Ullrich: EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. in Nature 2000 (PubMed)
    Show all 4 references for ABIN3201018

  2. Human Polyclonal HBEGF Primary Antibody for EIA, WB - ABIN952685 : Rahman, Kadowaki, Ishihara, Tobita, Imaoka, Fukuhara, Aziz, Furuta, Amano, Kinoshita: Fibroblast-derived HB-EGF promotes Cdx2 expression in esophageal squamous cells. in Laboratory investigation; a journal of technical methods and pathology 2010 (PubMed)
    Show all 4 references for ABIN952685

  3. Human Monoclonal HBEGF Primary Antibody for ICC, IF - ABIN2451994 : Miyamoto, Hirata, Yamazaki, Kageyama, Hasuwa, Mizushima, Tanaka, Yagi, Sonoda, Kai, Kanoh, Nakano, Mekada: Heparin-binding EGF-like growth factor is a promising target for ovarian cancer therapy. in Cancer research 2004 (PubMed)
    Show all 4 references for ABIN2451994

  4. Human Polyclonal HBEGF Primary Antibody for IF (p), IHC (p) - ABIN701050 : Lebkuechner, Wilhelmsson, Möllerström, Pekna, Pekny: Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency. in Journal of neurochemistry 2015 (PubMed)

  5. Human Polyclonal HBEGF Primary Antibody for WB - ABIN658749 : Hamaoka, Chinen, Murata, Takashima, Iwamoto, Mekada: Anti-human HB-EGF monoclonal antibodies inhibiting ectodomain shedding of HB-EGF and diphtheria toxin binding. in Journal of biochemistry 2010 (PubMed)

More Antibodies against HBEGF Interaction Partners

Zebrafish Heparin-Binding EGF-Like Growth Factor (HBEGF) interaction partners

  1. These results suggest that there is an EGF (show EGF Antibodies) signaling network in the zebrafish ovarian follicle, and the functionality of this network is self-regulated by its own members.

Human Heparin-Binding EGF-Like Growth Factor (HBEGF) interaction partners

  1. Data suggest that placental expression of HBEGF, EGF (show EGF Antibodies) (epidermal GF), and TGFA (show TGFA Antibodies) (transforming GF alpha) is down-regulated in pre-eclampsia as compared to normal term birth; each growth factor blocks cell death/apoptosis of cytotrophoblast cell line.

  2. Serum sHB (show SHB Antibodies)-EGF (show EGF Antibodies) is closely correlated with advanced stage gastric cancer and can be a promising serological biomarker for GC.

  3. Studies indicate that heparin-binding EGF-like growth factor (HB-EGF) is a therapeutic target in some types of cancers.

  4. the relative expression of hyalurosome (CD44 (show CD44 Antibodies), HAS3 (show HAS3 Antibodies), HB-EGF) genes was found to be reduced in patients prior to topical treatment and to be notably increased following treatment.

  5. Urinary levels of NGF (show NGFB Antibodies) and HB-EGF may be potential biomarkers for evaluating outcome of overactive bladder syndrome treatment.

  6. HB-EGF is a biomarker for LPA1 (show LPAR1 Antibodies) receptor activation in human breast and prostate cancers.

  7. MiR (show MLXIP Antibodies)-212 exerts suppressive effect on SKOV3 ovarian cancer cells through targeting HBEGF.

  8. Suggest high levels of HB-EGF contribute to carotid plaque stabilization and reduce the incidence of acute coronary events.

  9. Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo.

  10. studies suggest disintegrin and metalloproteinase domain-containing protein 12 (show ADAM12 Antibodies)(ADAM 12S) and heparin-binding epidermal growth factor-like growth factor(HB-EGF) are involved in cellular plasticity resulting in production of brown adipose tissue-like cells

Mouse (Murine) Heparin-Binding EGF-Like Growth Factor (HBEGF) interaction partners

  1. Pelvic irradiation increases versican (show Vcan Antibodies) expression in bladder and rectum.

  2. Psychiatric, social-behavioral and cognitive abnormalities were also observed in hippocampal Hbegf knockout mice.

  3. HB-EGF promotes enteric neural stem cell proliferation and migration in a mouse model

  4. mice in which DTR is expressed on conventional Dendritic cells display marked lymph node hypocellularity and reduced frequency of Dendritic cells in the same organs but not in spleen or nonlymphoid tissues.

  5. miR (show MLXIP Antibodies)-96 promotes osteogenic differentiation by inhibiting HB-EGF and by blocking the HB-EGF-EGFR (show EGFR Antibodies) signaling pathway in osteoblastic cells

  6. Reverse transcriptase polymerase chain reaction studies showed that three members, Tgfa, Hbegf,and Nrg1 of the EGF family were expressed in the epithelium cultured with FGF7 + LPA as well as in the epithelium freshly isolated from the rudiments.

  7. Decreased nitric oxide bioavailability leads to increased HB-EGF expression, which may be an important mediator of the resulting progressive diabetic nephropathy in eNOS (show NOS3 Antibodies)-knockout diabetic mice.

  8. HB-EGF changed morphology of 2D and Bioactive3D cultured astrocytes toward a radial glia-like phenotype and induced the expression of intermediate filament and progenitor cell marker protein nestin (show NES Antibodies).

  9. HB-EGF induction on Snail (show SNAI1 Antibodies) expression is dependent on the EGFR (show EGFR Antibodies)-ERK (show EPHB2 Antibodies)-Stat3 (show STAT3 Antibodies) pathway.

  10. miR (show MLXIP Antibodies)-1192 directly targets Hbegf through translational inhibition, suggesting enhancement of Runx2 (show RUNX2 Antibodies)-induced osteogenic differentiation by miR (show MLXIP Antibodies)-1192 through the downregulation of HB-EGF.

Cow (Bovine) Heparin-Binding EGF-Like Growth Factor (HBEGF) interaction partners

  1. These results indicate that HB-EGF and its receptors expression changed in bovine endometrium throughout the oestrous cycle; IFN-tau increased their expression in cultured endometrial cells.

  2. Heparin-binding EGF-like growth factor is main component in chromaffin granules responsible for neurotrophic effect on dopaminergic neurones. Protective effects on nigrostriatal dopaminergic neurones. Candidate for treatment of Parkinson's disease.

HBEGF Antigen Profile

Antigen Summary

Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

Alternative names and synonyms associated with HBEGF

  • heparin-binding EGF-like growth factor b (hbegfb) antibody
  • heparin-binding EGF-like growth factor (HBEGF) antibody
  • Heparin-binding EGF-like growth factor (hbegf) antibody
  • heparin-binding EGF-like growth factor a (hbegfa) antibody
  • heparin-binding EGF-like growth factor (LOC100232539) antibody
  • heparin-binding EGF-like growth factor (Hbegf) antibody
  • heparin-binding epidermal growth factor (LOC100008809) antibody
  • AW047313 antibody
  • Dtr antibody
  • Dts antibody
  • DTSF antibody
  • GFHB antibody
  • HB-EGF antibody
  • HBEGF antibody
  • Hegfl antibody
  • zgc:165443 antibody
  • zgc:175091 antibody

Protein level used designations for HBEGF

proheparin-binding EGF-like growth factor , heparin-binding EGF-like growth factor , Heparin-binding EGF-like growth factor , diphtheria toxin receptor (heparin-binding EGF-like growth factor) , diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor) , heparin-binding epidermal growth factor , Diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor) , heparin binding epidermal growth factor-like growth factor , heparin-binding epidermal -growth - like growth factor , heparin-binding epidermal -growth factor , diphtheria toxin receptor , heparin-binding epidermal growth factor-like growth factor

407664 Danio rerio
695559 Macaca mulatta
735979 Pan troglodytes
100305262 Oncorhynchus mykiss
607007 Canis lupus familiaris
797938 Danio rerio
100232539 Taeniopygia guttata
1839 Homo sapiens
25433 Rattus norvegicus
15200 Mus musculus
395654 Gallus gallus
397564 Sus scrofa
522921 Bos taurus
100008809 Oryctolagus cuniculus
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