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anti-Human HBEGF antibody for Enzyme Immunoassay

Recommended HBEGF Antibody (supplied by: Log in to see )

Antigen
Heparin-Binding EGF-Like Growth Factor (HBEGF) Antibodies
  • AW047313
  • Dtr
  • DTR
  • DTS
  • Dts
  • DTSF
  • GFHB
  • HB-EGF
  • Hb-egf
  • hbegf
  • HBEGF
  • HEGFL
  • Hegfl
  • zgc:165443
  • zgc:175091
Epitope
AA 67-96, Middle Region
15
13
13
11
6
6
5
4
3
2
2
2
1
1
1
Reactivity
Human
60
19
16
Host
Rabbit
50
13
Clonality
Polyclonal
Conjugate
This HBEGF antibody is un-conjugated
6
4
3
3
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
36
32
11
8
6
4
4
2
2
2
1
1
1
Supplier
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Catalog No. ABIN952685
$ 390.50
Plus shipping costs $45.00

Top referenced anti-HBEGF antibody for Enzyme Immunoassay

Similar anti-HBEGF Antibodies

Application / Reactivity Human
ELISA 30 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunofluorescence (IF) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 6 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 7 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Neutralization (Neut) 4 Antibodies
Western Blotting (WB) 36 Antibodies

General

Antigen Heparin-Binding EGF-Like Growth Factor (HBEGF) Antibodies
Epitope AA 67-96, Middle Region
(15), (13), (13), (11), (6), (6), (5), (4), (3), (2), (2), (2), (1), (1), (1)
Reactivity Human
(60), (19), (16)
Host Rabbit
(50), (13)
Clonality
Polyclonal
Conjugate This HBEGF antibody is un-conjugated
(6), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(36), (32), (11), (8), (6), (4), (4), (2), (2), (2), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-HBEGF Antibody

Target Details HBEGF Application Details Handling References for anti-HBEGF Antibody (ABIN952685) Images
Specificity This antibody recognizes Human HBEGF (Center).
Purification Protein A column, followed by peptide affinity purification
Immunogen KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of Human HBEGF
Isotype Ig

Target Details HBEGF

Product Details anti-HBEGF Antibody Application Details Handling References for anti-HBEGF Antibody (ABIN952685) Images back to top
Antigen
Alternative Name HBEGF (HBEGF Antibody Abstract)
Background HBEGF may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.Synonyms: DTR, DTS, HEGFL, Proheparin-binding EGF-like growth factor
Molecular Weight 23067 Da
Gene ID 1839
NCBI Accession NP_001936
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-HBEGF Antibody Target Details HBEGF Handling References for anti-HBEGF Antibody (ABIN952685) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-HBEGF Antibody Target Details HBEGF Application Details References for anti-HBEGF Antibody (ABIN952685) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-HBEGF Antibody (ABIN952685)

Product Details anti-HBEGF Antibody Target Details HBEGF Application Details Handling Images back to top
Background publications

Rahman, Kadowaki, Ishihara, Tobita, Imaoka, Fukuhara, Aziz, Furuta, Amano, Kinoshita: "Fibroblast-derived HB-EGF promotes Cdx2 expression in esophageal squamous cells." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 90, Issue 7, pp. 1033-48, 2010

Hamaoka, Chinen, Murata, Takashima, Iwamoto, Mekada: "Anti-human HB-EGF monoclonal antibodies inhibiting ectodomain shedding of HB-EGF and diphtheria toxin binding." in: Journal of biochemistry, Vol. 148, Issue 1, pp. 55-69, 2010

Smirnova, Gonchar, Shatrova, Nikolskiĭ, Burova: "[Metalloprotease-mediated HB-EGF release regulates EGF receptor transactivation in A431 cells under oxidative stress]." in: Tsitologiia, Vol. 52, Issue 5, pp. 357-63, 2010

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Images

Product Details anti-HBEGF Antibody Target Details HBEGF Application Details Handling References for anti-HBEGF Antibody (ABIN952685) back to top
Supplier Images
Western Blotting (WB) image for anti-HBEGF antibody (Heparin-Binding EGF-Like Growth Factor) (AA 67-96) (ABIN952685) Western blot analysis of HBEGF Antibody (Center) in K562 cell line lysates (35ug/lane...