Proto-oncogene c-Mer (C-mer) is a cell entry factor for filovirus. C-mer is not expressed in normal B- and T-lymphocytes but is expressed in numerous neoplastic B- and T-cell lines. Defects in C-mer are a cause of retinitis pigmentosa (RP) that leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
Each vial contains 0.1 mg IgG in 0.1 mL of PBS pH7.4 with 0.09% sodium azide.
Precaution of Use
Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.