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MERTK Products

(C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008].

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Featured MERTK Categories

MERTK Antibodies

High quality antibodies with extensive validation data.

MERTK ELISA Kits

Reliable ELISA kits for a wide range of species.

MERTK Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MERTK Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, IF, IHC, ELISA, WB
Validations
  • (7)
Cat. No. ABIN3030229
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application FACS, IF, IHC, WB
Validations
  • (5)
Cat. No. ABIN7042974
Quantity 0.2 mL
Datasheet Datasheet
Reactivity Human
Application IHC, IHC (f)
Validations
  • (4)
Cat. No. ABIN6939061
Quantity 100 μg
Datasheet Datasheet

Recommended MERTK ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN2703325
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965254
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954216
Quantity 96 tests
Datasheet Datasheet

Recommended MERTK Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275242
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275243
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275244
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MERTK products

Kubli, Bassi, Roux, Wakeham, Göbl, Zhou, Jafari, Snow, Jones, Palomero, Thu, Cassetta, Soong, Berger, Ramachandran, Baniasadi, Duncan, Lindzen, Yarden, Herranz, Lazaro, Chu, Haight, Tinto, Silvester et al.: "AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, Issue 9, pp. 3604-3613, (2019) (PubMed).

Zapatero-Belinchón, Dietzel, Dolnik, Döhner, Costa, Hertel, Veselkova, Kirui, Klintworth, Manns, Pöhlmann, Pietschmann, Krey, Ciesek, Gerold, Sodeik, Becker, von Hahn: "Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors." in: Viruses, Vol. 11, Issue 3, (2019) (PubMed).

Kasikara, Davra, Calianese, Geng, Spires, Quigley, Wichroski, Sriram, Suarez-Lopez, Yaffe, Kotenko, De Lorenzo, Birge: "Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer." in: Cancer research, Vol. 79, Issue 10, pp. 2669-2683, (2019) (PubMed).

Aran, Looney, Liu, Wu, Fong, Hsu, Chak, Naikawadi, Wolters, Abate, Butte, Bhattacharya: "Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage." in: Nature immunology, Vol. 20, Issue 2, pp. 163-172, (2019) (PubMed).

Nishi, Yanagihashi, Segawa, Nagata: "MERTK tyrosine kinase receptor together with TIM4 phosphatidylserine receptor mediates distinct signal transduction pathways for efferocytosis and cell proliferation." in: The Journal of biological chemistry, Vol. 294, Issue 18, pp. 7221-7230, (2019) (PubMed).

Santamaria-Barria, Zeng, Greer, Beckman, Seifert, Cohen, Zhang, Crawley, Green, Loo, Maltbaek, DeMatteo: "Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells." in: PLoS ONE, Vol. 14, Issue 5, pp. e0216275, (2019) (PubMed).

Macdougall, Wood, Loschko, Scagliotti, Cassidy, Robinson, Feldhahn, Castellano, Voisin, Marelli-Berg, Gaston-Massuet, Charalambous, Longhi: "Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets." in: Cell metabolism, Vol. 27, Issue 3, pp. 588-601.e4, (2019) (PubMed).

Carestia, Mena, Olexen, Ortiz Wilczyñski, Negrotto, Errasti, Gómez, Jenne, Carrera Silva, Schattner: "Platelets Promote Macrophage Polarization toward Pro-inflammatory Phenotype and Increase Survival of Septic Mice." in: Cell reports, Vol. 28, Issue 4, pp. 896-908.e5, (2019) (PubMed).

Triantafyllou, Pop, Possamai, Wilhelm, Liaskou, Singanayagam, Bernsmeier, Khamri, Petts, Dargue, Davies, Tickle, Yuksel, Patel, Abeles, Stamataki, Curbishley, Ma, Wilson, Coen, Woollard, Quaglia et al.: "MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure. ..." in: Gut, Vol. 67, Issue 2, pp. 333-347, (2018) (PubMed).

Kumar, Jovel, Lopez-Orozco, Limonta, Airo, Hou, Stryapunina, Fibke, Moore, Hobman: "Human Sertoli cells support high levels of Zika virus replication and persistence." in: Scientific reports, Vol. 8, Issue 1, pp. 5477, (2018) (PubMed).

Synonyms and alternative names related to MERTK

MER proto-oncogene, tyrosine kinase (MERTK), c-mer proto-oncogene tyrosine kinase (Mertk), MER proto-oncogene, tyrosine kinase (Mertk), c-mer proto-oncogene tyrosine kinase (MERTK), c-mer proto-oncogene tyrosine kinase a (mertka), C-EYK, c-mer, DKFZp469D2215, Eyk, MER, Mer, MERTK, nmf12, Nyk, rdy, RP38, si:ch1073-268l12.2

Protein level used designations for MERTK

  • MER receptor tyrosine kinase
  • STK kinase
  • proto-oncogene c-Mer
  • receptor tyrosine kinase MerTK
  • tyrosine-protein kinase Mer
  • Tyro 12
  • proto-oncogene tyrosine-protein kinase Mer
  • Receptor tyrosine tinase gene probably the gene for Rdy
  • proto-oncogene tyrosine-protein kinase MER
  • retinal dystrophy
  • c-eyk proto-oncogene
  • c-mer proto-oncogene tyrosine kinase
  • tyrosine-protein kinase Mer-like
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